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公开(公告)号:US11867631B2
公开(公告)日:2024-01-09
申请号:US17527828
申请日:2021-11-16
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
IPC: G01N21/65 , G01N21/47 , G01N21/63 , G01N21/66 , G01N33/18 , G01J3/02 , G01J3/18 , G01J3/44 , B01L3/00 , G01N27/447 , G01N30/60 , G01N21/49 , G01N21/68 , G01N21/27 , G01N30/00 , G01J3/28
CPC classification number: G01N21/65 , B01L3/502715 , B01L3/502761 , G01J3/02 , G01J3/0256 , G01J3/0291 , G01J3/18 , G01J3/44 , G01J3/4412 , G01N21/276 , G01N21/47 , G01N21/4785 , G01N21/49 , G01N21/63 , G01N21/658 , G01N21/66 , G01N21/68 , G01N27/44704 , G01N27/44791 , G01N30/6095 , G01N33/18 , B01L2200/04 , B01L2200/0652 , B01L2200/12 , B01L2300/0627 , B01L2300/0636 , B01L2300/0654 , B01L2300/0681 , B01L2300/087 , B01L2300/0867 , B01L2400/0418 , B01L2400/0421 , G01J2003/2866 , G01J2003/2879 , G01N30/6065 , G01N2021/651 , G01N2021/656 , G01N2030/0095 , G01N2201/0221 , G01N2201/13
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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公开(公告)号:US20220146430A1
公开(公告)日:2022-05-12
申请号:US17527844
申请日:2021-11-16
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
IPC: G01N21/65 , G01N21/47 , G01J3/18 , G01J3/44 , B01L3/00 , G01N27/447 , G01N30/60 , G01J3/02 , G01N21/66 , G01N21/63 , G01N21/49 , G01N21/68 , G01N33/18
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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公开(公告)号:US20220074862A1
公开(公告)日:2022-03-10
申请号:US17527828
申请日:2021-11-16
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
IPC: G01N21/65 , G01N21/47 , G01J3/18 , G01J3/44 , B01L3/00 , G01N27/447 , G01N30/60 , G01J3/02 , G01N21/66 , G01N21/63 , G01N21/49 , G01N21/68 , G01N33/18
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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4.
公开(公告)号:US10895564B2
公开(公告)日:2021-01-19
申请号:US16870530
申请日:2020-05-08
Applicant: OndaVia, Inc.
Inventor: Mark Charles Peterman , Merwan Benhabib , Carlos Atico Ariza , Samuel Louis Kleinman
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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公开(公告)号:US11994455B2
公开(公告)日:2024-05-28
申请号:US17710244
申请日:2022-03-31
Applicant: OndaVia, Inc.
Inventor: Mark Charles Peterman , Merwan Benhabib
IPC: G01N15/06 , G01J3/44 , G01N15/075
CPC classification number: G01N15/06 , G01J3/4406 , G01N15/075
Abstract: An analyte in water is quantified by mixing an internal standard with a water sample. The sample is analyzed with a Raman spectrometer. The analysis includes mapping the signal from the Raman spectrometer to the quantity of said analyte. The mapping can include using a calibration curve, for example a multivariate calibration curve, that was previously prepared with the internal standard. In other examples, a sample is measured after addition of a known amount of the analyte.
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公开(公告)号:US20190257760A1
公开(公告)日:2019-08-22
申请号:US16280651
申请日:2019-02-20
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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7.
公开(公告)号:US09863924B2
公开(公告)日:2018-01-09
申请号:US15267708
申请日:2016-09-16
Applicant: ONDAVIA, INC.
Inventor: Mark Charles Peterman , Merwan Benhabib , Carlos Atico Ariza , Samuel Louis Kleinman
CPC classification number: G01N33/18 , G01N21/658 , G01N33/182
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analog of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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8.
公开(公告)号:US10444216B2
公开(公告)日:2019-10-15
申请号:US15821098
申请日:2017-11-22
Applicant: OndaVia, Inc.
Inventor: Mark Charles Peterman , Merwan Benhabib , Carlos Atico Ariza , Samuel Louis Kleinman
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analog of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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公开(公告)号:US10254229B2
公开(公告)日:2019-04-09
申请号:US14198163
申请日:2014-03-05
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
IPC: G01N21/65 , B01L3/00 , G01J3/18 , G01J3/44 , G01N21/47 , G01N30/60 , G01N27/447 , G01N33/18 , G01N30/00
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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公开(公告)号:US10247673B2
公开(公告)日:2019-04-02
申请号:US15239153
申请日:2016-08-17
Applicant: OndaVia, Inc.
Inventor: Mark C. Peterman , Merwan Benhabib , Samuel Kleinman
IPC: G01J3/18 , G01N21/47 , G01N21/65 , G01N33/18 , G01J3/44 , B01L3/00 , G01N30/60 , G01N27/447 , G01N30/00
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
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