Abstract:
PURPOSE: To obtain a composition capable of promoting the healing of living animal tissue, especially the healing of human dermis by dispersing vesicles obtained from a nonionic lipid combined with cholesterol into an aqueous phase in a specific concentration. CONSTITUTION: This composition is obtained by dispersing vesicles obtained from a combination of a nonionic lipid represented by the formula [R is a 16-18C alkyl or its mixture or R'CO (R' is 15-17C alkyl or its mixture)] with cholesterol and further preferably dicetyl phosphate or tetradecyl phosphate (especially the form of Na salt) and having 25-5,000nm, preferably 100-500nm average diameter and
Abstract:
PURPOSE: To obtain the subject composition containing vesicles obtained by combining a nonionic lipid with cholesterol and an anionic stabilizer, and a perfumery of a high concentration free from a lower alcohol in a continuous aqueous phase. CONSTITUTION: This continuous aqueous phase perfumery composition contains vesicles having 0.01-1μ mean diameter and obtained by a nonionic lipid consisting of a polyglycerol derivative of formula I or II [(n) is a statistical mean value of 2-6; R is a 12-18C aliphatic group (R1 ), R2 CO (R2 is a 11-17C aliphatic group) or a group of formula III (R3 , R4 are each R1 or R2 CO)], and a perfumery having small droplets shape and 0.1-1μ mean diameter containing a natural essential oil or a synthetic material having an aroma, and free from a 1-4C alcohol. The nonionic lipid contains cholesterol and an anionic stabilizer. The above composition contains a high concentration (3-20wt.%) perfumery, and can exert a calming effect to a skin without disturbing an aromatic tone.
Abstract:
PURPOSE: To obtain an anhydrous cosmetic makeup compsn. contg. a fat phase mixed with a provesicle lipid phase capable of forming vesicles in the presence of water. CONSTITUTION: A fat phase consisting of oil, a fat base and a surfactant is mixed with a provesicle lipid phase contg. at least one kind of amphipatic lipid capable of forming vesicles by contact with an aq. phase. The amphipatic lipid is, e.g. ionic amphipatic lipid represented by the formula (R1 is 7-21C alkyl or alkenyl, R2 is a residue of satd. or unsatd. 7-31C hydrocarbon and M is H, Na, K, NH4 or an ammonium ion derived from an amine) or nonionic amphipatic lipid such as straight chain or branched chain polyglycerol ether having two aliphatic chains, aliphatic alcohol having polyoxyethylene, natural or synthetic glycolipid. It is preferably that a cosmetically active material or a dermatologically active material is further incorporated into the resultant anhydrous compsn.
Abstract:
PURPOSE: To obtain a compsn. for cosmetics or for dermatological pharmacy made of an aq. dispersion of lipid vesicles. CONSTITUTION: The constituent lipids of at least some partition wall layers of the vesicles include 50-75% phospholipid and 50-25% glycolipid contg. 1-5% ganglioside. These lipids may be extracted from the membranes of small fat spheres of mammalian milk, especially cow's butter milk.
Abstract:
PURPOSE: To obtain a compsn. which consists of a stabilized water-based dispersion liquid of small particles of several nonionic amphiphilic lipids without deterioration during storage and which is useful for preparation of a cosmetic product and dermatologic drug. CONSTITUTION: This compsn. consists of a water-based dispersion liquid of lipid particles containing (A) nonionic amphiphilic lipids and (B) ionic ampiphilic lipids such as phospholipid which give 5.5 to 7.5 pH to the dispersion liquid. The nonionic amphiphilic lipids (A) consist of an ester mixture of fatty acids having 5 to 17C alkyl chains and polyols selected from polyethylene glycol and sorbitan each having 1 to 60 ethylene oxide(EO) units, sorbitan having 2 to 60 EO units, glycerol having 2 to 30 EO units, polyglycerol and sucrose each having 2 to 15 glycerol units, and glucose having 20 to 30 EO units, and the lipids (A) has 1 to 10 chains per one polyol. The weight ratio of A:B is 50:1 to 50:25, and the weight ratio of the lipid phase to the water-based dispersion phase is 1:1,000 to 300:1,000.