公开(公告)号：DE60010677D1

公开(公告)日：2004-06-17

申请号：DE60010677

申请日：2000-02-18

Applicant: PACKARD INSTRUMENT CO INC

Inventor： DUEBENDORFER JUERG ,  JONES DONALD ,  NEUMANN KENNETH ,  WANG CHANG

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25 ,  G01N35/02

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.

公开(公告)号：AT266856T

公开(公告)日：2004-05-15

申请号：AT00915795

申请日：2000-02-18

Applicant: PACKARD INSTRUMENT CO INC

Inventor： DUEBENDORFER JUERG ,  JONES DONALD ,  NEUMANN KENNETH ,  WANG CHANG

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25 ,  G01N35/02

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.

公开(公告)号：DE60010677T2

公开(公告)日：2004-10-07

申请号：DE60010677

申请日：2000-02-18

Applicant: PACKARD INSTRUMENT CO INC

Inventor： DUEBENDORFER JUERG ,  JONES DONALD ,  NEUMANN KENNETH ,  WANG CHANG

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25 ,  G01N35/02

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.

公开(公告)号：AU3701000A

公开(公告)日：2000-09-14

申请号：AU3701000

申请日：2000-02-18

Applicant: PACKARD INSTRUMENT CO INC

Inventor： DUEBENDORFER JUERG ,  JONES DONALD ,  NEUMANN KENNETH ,  WANG CHANG

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.

公开(公告)号：EP1163497A4

公开(公告)日：2002-04-24

申请号：EP00915795

申请日：2000-02-18

Applicant: PACKARD INSTRUMENT CO INC

Inventor： DUEBENDORFER JUERG ,  JONES DONALD ,  NEUMANN KENNETH ,  WANG CHANG

IPC: G01N21/64 ,  G01J3/30 ,  G01J1/58 ,  G01N21/25 ,  G01N35/02

CPC classification number: G01N21/6452 ,  G01N2201/0648

Abstract: An apparatus for measuring light in samples using a high intensity light source (12), is presented. The system utilizes bifurcated fiber bundle (26) to transmit light at the excitation and emission wavelength bands. It also uses a band-pass filter (36) for eliminating extraneous light, including that which corresponds to the excitation wavelength range, while permitting the emitted light to pass to a detector (41) for quantitation. The system employs a shutter (39) to shield the detector (41) while the laser light source is activated, and a controller to intermittently activate the laser light and close the shutter. The apparatus preferably includes lenses (16, 17, 37) for better illumination and read out conditions. The apparatus is employed in Luminescence Oxygen Channeling Immunoassays. The method has high sensitivity, accuracy and precision, and the apparatus is highly compact. Accordingly, the analyzer can perform assays in nanoliter to microliter sample volumes in standard microplates having at least 96, 384 or 1536 wells.