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    PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS
    1.
    发明申请
    PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENTS AND A COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTIONS 审中-公开
    纯生物活性化合物，其组分和用于治疗肺炎的COLISTIN制剂

    公开(公告)号：WO9820836A2

    公开(公告)日：1998-05-22

    申请号：PCT/US9721829

    申请日：1997-11-13

    Applicant: PATHOGENESIS CORP

    Inventor： VANDEVANTER DONALD R ,  MONTGOMERY ALAN B

    IPC: A61K9/12 ,  A61K9/00 ,  A61K38/00 ,  A61K38/12 ,  A61P11/00 ,  A61P31/04 ,  C07K7/50 ,  C07K7/62 ,  A61K

    CPC classification number: A61K9/0078 ,  A61K38/12 ,  C07K7/62

    Abstract: An anti-Pseudomonas aeruginosa agent which is substantially pure biologically active colistin component, a mixture thereof or a pharmaceutically acceptable salt thereof delivered as an aerosol or dry powder formulation. A formulation and method for preparation of substantially pure biologically active colistin, its components, mixtures thereof and a pharmaceutically acceptable salts thereof. A method for treatment and prophylaxis of Pseudomonas aeruginosa, Stenotrophomonas maltophilia or other susceptible pulmonary bacterial infections.

    Abstract translation: 作为气溶胶或干粉制剂递送的基本上纯的生物活性粘菌素组分，其混合物或其药学上可接受的盐的抗绿脓假单胞菌试剂。 用于制备基本上纯的生物活性粘菌素，其组分，其混合物及其药学上可接受的盐的制剂和方法。 一种治疗和预防铜绿假单胞菌，嗜麦芽寡养单胞菌或其他易感性肺细菌感染的方法。

    Pure biologically active colistin, its component and colistin formulation for treatment of pulmonary infection
    2.
    发明专利
    Pure biologically active colistin, its component and colistin formulation for treatment of pulmonary infection 审中-公开
    纯生物活性组蛋白，其组分和组合物用于治疗肺部感染

    公开(公告)号：JP2007302698A

    公开(公告)日：2007-11-22

    申请号：JP2007213191

    申请日：2007-08-17

    Applicant: Pathogenesis Corp ,  パソジェネシス コーポレイション

    Inventor： VANDEVANTER DONALD R ,  MONTGOMERY ALAN B

    IPC: A61K9/12 ,  A61K38/00 ,  A61K9/00 ,  A61K9/72 ,  A61K38/12 ,  A61P11/00 ,  A61P31/04 ,  C07K7/50 ,  C07K7/62

    CPC classification number: A61K9/0078 ,  A61K38/12 ,  C07K7/62

    Abstract: PROBLEM TO BE SOLVED: To provide a pure biologically active colistin, its component, and a colistin formulation for the treatment of pulmonary infection. SOLUTION: The pure biologically active colistin, all its components, a given mixture thereof or a pharmaceutically acceptable salt thereof and an aerosol formulation containing the substantially pure biologically active colistin, any of its biologically active components, a mixture thereof or a pharmaceutically acceptable salt thereof are provided. The formulation is suitable for atomization, and an atomized form offers an effective treatment and prevention of Pseudomonas aeruginosa infection or other susceptible pulmonary infections (e.g. Stenotrophomonas maltophilia). COPYRIGHT: (C)2008,JPO&INPIT

    Abstract translation: 要解决的问题：提供纯生物活性的粘菌素，其组分和用于治疗肺部感染的粘菌素制剂。 解决方案：纯生物活性粘菌素，其所有组分，给定的混合物或其药学上可接受的盐和含有基本上纯的生物活性粘菌素，其任何生物活性成分，其混合物或药学上可接受的盐 提供其可接受的盐。 该制剂适用于雾化，并且雾化形式提供铜绿假单胞菌感染或其他敏感性肺部感染（例如嗜麦芽寡养单胞菌（Stenotrophomonas maltophilia））的有效治疗和预防。 版权所有（C）2008，JPO＆INPIT

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