公开(公告)号：US10188967B2

公开(公告)日：2019-01-29

申请号：US14560273

申请日：2014-12-04

Applicant: POCARED Diagnostics LTD.

Inventor： Gal Ingber ,  Scott Castanon

IPC: C12Q1/24 ,  B01D29/00 ,  B01D37/00 ,  G01N1/40 ,  G01G17/06 ,  G01N33/493 ,  B01L3/00 ,  G01N5/02 ,  G01N15/00 ,  G01F15/12

Abstract: A filter arrangement with a top element and a bottom element and a filter element therebetween captures oversized particles on the upper surface of the filter element and tangentially rinses these particles using an elution fluid to provide a concentration of particles in a relatively low volume of fluid for further analysis. A configuration using a slider valve may also be utilized. Additionally, an arrangement of supply and receiving containers may be used to minimize the number of containers required. A mass flow meter may be incorporated to measure the flow of elution fluid. Finally, a wash stage of the filtering process may be used to introduce stain onto the particles for further analysis, such as that associated with Gram staining and these stained particles may be further analyzed.

公开(公告)号：US20150152467A1

公开(公告)日：2015-06-04

申请号：US14560273

申请日：2014-12-04

Applicant: POCARED Diagnostics LTD.

Inventor： Gal Ingber ,  Scott Castanon

IPC: C12Q1/24 ,  B01D29/00 ,  G01N1/40 ,  B01D37/00

CPC classification number: B01D29/0095 ,  B01D37/00 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2400/0487 ,  B01L2400/0622 ,  B01L2400/065 ,  C12Q1/24 ,  G01F15/125 ,  G01G17/06 ,  G01N1/2813 ,  G01N1/30 ,  G01N1/4077 ,  G01N5/02 ,  G01N33/493 ,  G01N2001/4088 ,  G01N2015/0053 ,  Y10T436/25375

Abstract: A filter arrangement with a top element and a bottom element and a filter element therebetween captures oversized particles on the upper surface of the filter element and tangentially rinses these particles using an elution fluid to provide a concentration of particles in a relatively low volume of fluid for further analysis. A configuration using a slider valve may also be utilized. Additionally, an arrangement of supply and receiving containers may be used to minimize the number of containers required. A mass flow meter may be incorporated to measure the flow of elution fluid. Finally, a wash stage of the filtering process may be used to introduce stain onto the particles for further analysis, such as that associated with Gram staining and these stained particles may be further analyzed.

Abstract translation: 具有顶部元件和底部元件以及过滤元件的过滤器装置在过滤器元件的上表面上捕获过大的颗粒，并使用洗脱流体切向冲洗这些颗粒，以提供相对低体积的流体中的颗粒浓度 进一步分析。 还可以使用使用滑阀的构造。 此外，供应和接收容器的布置可以用于最小化所需容器的数量。 可以结合质量流量计来测量洗脱流体的流动。 最后，过滤过程的洗涤阶段可用于在颗粒上引入污染物用于进一步分析，例如与革兰氏染色相关的染色，并且可以进一步分析这些染色的颗粒。