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公开(公告)号:WO2021023634A1
公开(公告)日:2021-02-11
申请号:PCT/EP2020/071581
申请日:2020-07-30
Applicant: PROCOS S.P.A.
Inventor: COLOMBANO, Giampiero , BARBERO, Mauro , BOGOGNA, Luigi , ROLETTO, Jacopo , PAISSONI, Paolo
IPC: C07D295/088 , C07D471/10
Abstract: Disclosed is a process for the synthesis of pitolisant HCl of formula (I), from piperidine and 1-bromo-3-chloropropane. The process according to the invention is economically efficient and easily industrially scalable.