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Patent Agency Ranking
公开(公告)号：US20160004060A1
公开(公告)日：2016-01-07
申请号：US14735959
申请日：2015-06-10
Applicant: PURDUE RESEARCH FOUNDATION
Inventor： Garth Jason Simpson , Charles Addison Bouman , Ryan Douglas Muir , Shane Sullivan , Justin Allen Newman , Mark Carlsen
CPC classification number: G02B21/0084 , G02B21/0048 , G02B21/0076 , G02B26/101
Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
Abstract translation: 描述了用于在多个同时数据采集通道上实现高达kHz帧频光学成像的波束扫描光学设计。 在一个实施例中，两个快速扫描谐振反射镜将光束引导通过视场的迂回轨迹，轨迹重复时间由反射镜周期的最小公倍数给出。 将原始时域数据划分为与基于模型的图像重建（MBIR）相结合的子轨迹。3D绘图算法允许比Lissajous轨迹的重复时间高得多的有效帧速率。 因为子轨迹和全轨迹成像是分析相同数据的不同方法，同时获取具有较低分辨率的高帧率图像和高分辨率的低帧率图像。
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公开(公告)号：US10409047B2
公开(公告)日：2019-09-10
申请号：US15724738
申请日：2017-10-04
Applicant: PURDUE RESEARCH FOUNDATION
Inventor： Garth Jason Simpson , Charles Addison Bouman , Ryan Douglas Muir , Shane Sullivan , Justin Allen Newman , Mark Carlsen , Suhas Sreehari
Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
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公开(公告)号：US20230221591A1
公开(公告)日：2023-07-13
申请号：US18096619
申请日：2023-01-13
Applicant: Purdue Research Foundation
Inventor： Chi Zhang , Mark Carlsen , Matthew Clark
Abstract: The invention generally relates to systems and methods for controlling molecules. In certain aspects, the invention provides a system for controlling molecules, the system comprising: a first light source; a second light source; an acousto-optic modulator (AOM) coupled to the second light source; and control circuitry. In certain embodiments, the control circuitry may be configured to: receive a signal from the first light source that is interrogating a location in a sample that may contain a target molecule; compare the signal received from the first light source to a preset signal; and in the event that the signal received from the first light source meets or exceeds the preset signal, then the target molecule is present at the location in the sample and the control circuitry causes the AOM to activate the second light source to transmit light onto the location in the sample that contains the target molecule.
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公开(公告)号：US09784960B2
公开(公告)日：2017-10-10
申请号：US14735959
申请日：2015-06-10
Applicant: PURDUE RESEARCH FOUNDATION
Inventor： Garth Jason Simpson , Charles Addison Bouman , Ryan Douglas Muir , Shane Sullivan , Justin Allen Newman , Mark Carlsen , Suhas Sreehari
CPC classification number: G02B21/0084 , G02B21/0048 , G02B21/0076 , G02B26/101
Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
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公开(公告)号：US20180045939A1
公开(公告)日：2018-02-15
申请号：US15724738
申请日：2017-10-04
Applicant: PURDUE RESEARCH FOUNDATION
Inventor： Garth Jason Simpson , Charles Addison Bouman , Ryan Douglas Muir , Shane Sullivan , Justin Allen Newman , Mark Carlsen , Suhas Sreehari
CPC classification number: G02B21/0084 , G02B21/0048 , G02B21/0076 , G02B26/101
Abstract: A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors direct the optical beam on a circuitous trajectory through the field of view, with the trajectory repeat-time given by the least common multiplier of the mirror periods. Dicing the raw time-domain data into sub-trajectories combined with model-based image reconstruction (MBIR) 3D in-painting algorithms allows for effective frame-rates much higher than the repeat time of the Lissajous trajectory. Because sub-trajectory and full-trajectory imaging are different methods of analyzing the same data, both high-frame rate images with relatively low resolution and low frame rate images with high resolution are simultaneously acquired.
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