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1.发明申请ACTIVE INGREDIENT CONTAINING STABILISED SOLID MEDICINAL FORMS AND METHOD FOR THE PRODUCTION THEREOF 有权含有稳定的固体药物形式的活性成分及其生产方法公开(公告)号：US20090270515A1
公开(公告)日：2009-10-29
申请号：US12441629
申请日：2007-09-14
Applicant: Peter Gruber , Dirk Spickermann
Inventor： Peter Gruber , Dirk Spickermann
CPC classification number: A61K9/2009 , A61K9/1611
Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
Abstract translation: 本发明涉及含有至少一种活性成分和至少一种药学上相容的水溶性干燥剂的固体药物形式，其选自氯化三钙和/或氯化钙，固体药物形式具有干燥损失 最多6％，相对平衡含水量25％以下。 本发明还涉及含有湿敏性活性成分和十六酸镁的固体药物形式。
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2.发明授权公开(公告)号：US09775807B2
公开(公告)日：2017-10-03
申请号：US12441629
申请日：2007-09-14
Applicant: Peter Gruber , Dirk Spickermann
Inventor： Peter Gruber , Dirk Spickermann
CPC classification number: A61K9/2009 , A61K9/1611
Abstract: The invention relates to solid medicinal forms containing at least one active ingredient and at least one pharmaceutically compatible, water soluble drying agent which is selected from the group consisting of trimagnesium dicitrate and/or calcium chloride, the solid medicinal form having a drying loss of at most 6% and a relative equilibrium moisture content of 25% or less. The invention also relates to solid medicinal forms containing a moisture-sensitive active ingredient and trimagnesium dicitrate.
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