公开(公告)号：US20230391767A1

公开(公告)日：2023-12-07

申请号：US18453308

申请日：2023-08-21

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Herman O. SINTIM ,  Mohamed SELEEM ,  Clement OPOKU-TEMENG ,  Haroon Taj MOHAMMAD ,  George NACLERIO

IPC: C07D417/14 ,  A61P31/04 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14

CPC classification number: C07D417/14 ,  A61P31/04 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14

Abstract: The present invention generally relates to compounds as a new antibiotic to treat various infections, including infections caused by methicillin-resistant Staphylococcus aureus, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis and Clostridioides difficile. Pharmaceutical compositions and methods for treating those diseases are within the scope of this invention.

公开(公告)号：US20210047316A1

公开(公告)日：2021-02-18

申请号：US17046957

申请日：2019-03-29

Applicant: Purdue Research Foundation

Inventor： Herman O. SINTIM ,  Mohamed SELEEM ,  Clement OPOKU-TEMENG ,  Haroon Taj MOHAMMAD ,  George NACLERIO

IPC: C07D417/14 ,  C07D413/12 ,  C07D413/14 ,  C07D409/14 ,  A61P31/04

Abstract: The present invention generally relates to compounds as a new antibiotic to treat various infections, including infections caused by methicillin-resistant Staphylococcus aureus, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis and Clostridioides difficile. Pharmaceutical compositions and methods for treating those diseases are within the scope of this invention.