公开(公告)号：US20160251699A1

公开(公告)日：2016-09-01

申请号：US15054176

申请日：2016-02-26

Applicant: Purdue Research Foundation

Inventor： Muhammad Ashraful Alam ,  Piyush Dak

IPC: C12Q1/68

CPC classification number: C12Q1/686 ,  C12Q1/6806 ,  C12Q2563/116 ,  C12Q2563/159 ,  C12Q2565/607

Abstract: A process and device for electrostatically controlling an ionic environment in a droplet, such as in a droplet-based platform including polymerase-chain reaction (PCR) applications. The process includes providing a chip that comprises at least a pair of electrodes, placing a salt-containing droplet on the chip, and then applying a bias across the electrodes to accumulate ions near surfaces of the electrodes, thereby depleting a bulk salt concentration in regions of the droplet away from the electrodes.

Abstract translation: 用于静电控制液滴中的离子环境的方法和装置，例如在基于液滴的平台中，包括聚合酶链反应（PCR）应用。 该方法包括提供包括至少一对电极的芯片，将含盐的液滴放置在芯片上，然后在电极上施加偏压以在电极的表面附近积聚离子，从而消耗区域中的体盐浓度 的液滴远离电极。

公开(公告)号：US20200248230A1

公开(公告)日：2020-08-06

申请号：US16560960

申请日：2019-09-04

Applicant: Purdue Research Foundation

Inventor： Muhammad Ashraful Alam ,  Piyush Dak

IPC: C12Q1/686 ,  C12Q1/6806

Abstract: A process and device for electrostatically controlling an ionic environment in a droplet, such as in a droplet-based platform including polymerase-chain reaction (PCR) applications. The process includes providing a chip that comprises at least a pair of electrodes, placing a salt-containing droplet on the chip, and then applying a bias across the electrodes to accumulate ions near surfaces of the electrodes, thereby depleting a bulk salt concentration in regions of the droplet away from the electrodes.