公开(公告)号：WO1988006860A1

公开(公告)日：1988-09-22

申请号：PCT/DK1988000043

申请日：1988-03-11

Applicant: RADIOMETER A/S

Inventor： RADIOMETER A/S ,  HOJGAARD, Liselotte ,  SAKSAGER, Kim ,  KRAG, Einer ,  ANDERSEN, Jens, Rikardt ,  LINNET, Niels, Dürkopp ,  OLSEN, Frank, Nygaard

IPC: A61B05/04

CPC classification number: A61B5/14542 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/4238

Abstract: The in vivo determination of an electrical potential difference across a human or animal membrane of a fluid-containing cavity, such as the stomach (200), is performed by arranging (e.g. via an endoscope (201)) a measuring half cell (20) (electrode and electrolyte) in its entirety within the cavity and in contact with the cavity fluid, and arranging a reference half cell (50) in contact with a human or animal fluid outside the cavity, typically the blood, suitably via a catheter (87). The concentration of a species such as a H concentration in gastric juice contributing significantly to a liquid junction potential between the measuring electrolyte and the cavity fluid is measured, preferably by means of a sensor such as a pH sensor (110), preferably arranged within the cavity, and a relevant correction of the potential difference measured is based on said concentration measurement.

Abstract translation: 通过布置（例如经由内窥镜（201））测量半电池（20）来执行穿过诸如胃（200）的流体容纳腔的人或动物膜之间的电势差的体内测定， （电极和电解质）整体在空腔内并与空腔流体接触，并且通过导管（87）适当地布置参考半电池（50）与空腔外的人或动物流体（通常为血液）接触 ）。 优选地，通过诸如pH传感器（110）的传感器，优选地测量在测量电解质和腔体流体之间显着影响液体接合电位的胃液中的H ++浓度物质的浓度，优选地 排列在空腔内，并且所测量的电位差的相关校正基于所述浓度测量。