公开(公告)号：EP2265605A4

公开(公告)日：2011-08-03

申请号：EP09722911

申请日：2009-03-18

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB LTD DR

Inventor： KOLLA NAVEEN KUMAR ,  MANNE NAGARAJU ,  GANGULA SRINIVAS ,  NEELAM UDAYKUMAR ,  NAREDLA ANITHA ,  BADDAM SUDHAKAR REDDY ,  PATIL SUMEET VISHWASRAO ,  TUMMALA ARJUNKUMAR ,  PEDDIREDDY SUBBAREDDY ,  SHINDE SACHIN GULABRAO ,  SIGALA ASHOK ,  MUDUNURU SATISH VARMA ,  TUMMIDI MADHU KIRAN

IPC: C07D401/12 ,  A61K9/14 ,  A61K31/4439 ,  A61K47/32 ,  A61K47/38

CPC classification number: C07D401/12 ,  A61K9/1635 ,  A61K9/1652 ,  A61K47/6951 ,  B82Y5/00

公开(公告)号：WO2009149053A3

公开(公告)日：2010-05-14

申请号：PCT/US2009045920

申请日：2009-06-02

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR ,  KOLLA NAVEEN KUMAR ,  GANGULA SRINIVAS ,  NAREDLA ANITHA ,  BADDAM SUDHAKAR REDDY ,  PATIL SUMEET VISHWASRAO ,  SIGALA ASHOK ,  CHITTAPATHINA RAGHUNATH BABU VENKATA ,  MEDISETTI RAMA KRISHNA VENKATA ,  MANUDHANE KUSHAL SURAJMAL ,  NARRA SANTOSH REDDY ,  KOTAGIRI VIJAYA KUMAR

Inventor： KOLLA NAVEEN KUMAR ,  GANGULA SRINIVAS ,  NAREDLA ANITHA ,  BADDAM SUDHAKAR REDDY ,  PATIL SUMEET VISHWASRAO ,  SIGALA ASHOK ,  CHITTAPATHINA RAGHUNATH BABU VENKATA ,  MEDISETTI RAMA KRISHNA VENKATA ,  MANUDHANE KUSHAL SURAJMAL ,  NARRA SANTOSH REDDY ,  KOTAGIRI VIJAYA KUMAR

IPC: C07C201/02 ,  A61K31/21 ,  C07C203/04

CPC classification number: C07C201/02 ,  C07B2200/13 ,  C07C69/734 ,  C07C203/04

Abstract: Processes for the preparation of naproxcinod and its purification, solid dispersions of naproxcinod with a pharmaceutically acceptable carrier, and processes for making dispersions. Also provided is crystalline 2-(S)-(4-chlorobutyl)-2-(6-methoxy-2-naphthyl)-propanoate and methods for its preparation.

Abstract translation: 用于制备萘普生和其纯化的方法，萘普生与药学上可接受的载体的固体分散体，以及制备分散体的方法。 还提供了2-（S） - （4-氯丁基）-2-（6-甲氧基-2-萘基） - 丙酸酯的结晶及其制备方法。

公开(公告)号：CA2717578A1

公开(公告)日：2009-09-24

申请号：CA2717578

申请日：2009-03-18

Applicant: REDDYS LAB LTD DR ,  REDDYS LAB INC DR

Inventor： KOLLA NAVEEN KUMAR ,  MANNE NAGARAJU ,  GANGULA SRINIVAS ,  NEELAM UDAYKUMAR ,  NAREDLA ANITHA ,  BADDAM SUDHAKAR REDDY ,  PATIL SUMEET VISHWASRAO ,  TUMMALA ARJUNKUMAR ,  PEDDIREDDY SUBBAREDDY ,  SHINDE SACHIN GULABRAO ,  SIGALA ASHOK ,  MUDUNURU SATISH VARMA ,  TUMMIDI MADHU KIRAN

IPC: C07D403/12 ,  C07D235/24 ,  C07D235/28

Abstract: Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.

公开(公告)号：MX2010010049A

公开(公告)日：2010-10-04

申请号：MX2010010049

申请日：2009-03-18

Applicant: REDDYS LAB LTD DR

Inventor： PEDDIREDDY SUBBAREDDY ,  KOLLA NAVEEN KUMAR ,  MANNE NAGARAJU ,  GANGULA SRINIVAS ,  NEELAM UDAYKUMAR ,  NAREDLA ANITHA ,  BADDAM SUDHAKAR REDDY ,  PATIL SUMEET VISHWASRAO ,  SHINDE SACHIN GULABRAO ,  SIGALA ASHOK ,  MUDUNURU SATISH VARMA ,  TUMMIDI MADHU KIRAN ,  TUMMALA ARJUNKUMAR

IPC: C07D403/12 ,  C07D235/24 ,  C07D235/28

Abstract: Procesos para la preparación de dexlansoprazol, una forma amorfa de dexlansoprazol, una dispersión sólida de dexlansoprazol amorfo y un portador farmacéuticamente aceptable, y procesos para su preparación. También se proporcionan compuestos de 2-[(R)-[(4-cloro-3-metil-2-piridinil)metil]sulfinil]-1H-benzimida zol cristalino y 2-[(R)-[(4-nitro-3-metil-2-piridinil)metil]sulfin il]-1H-benzimidazol, y métodos para su preparación.