公开(公告)号：US09254082B2

公开(公告)日：2016-02-09

申请号：US14203595

申请日：2014-03-11

Applicant: RIKEN

Inventor： Satoshi Wada ,  Kazuo Tsubota ,  Atsushi Shinjo

IPC: A61B3/10 ,  A61B3/117

CPC classification number: A61B3/1173

Abstract: The present invention provides a method of measuring the elasticity of crystalline lens and an apparatus for measuring the elasticity of the crystalline lens for measuring stiffness of the crystalline lens 1, wherein the crystalline lens 1 is irradiated with pulse laser light to generate photoelastic waves from the crystalline lens 1, and the photoelastic waves from the crystalline lens 1 are measured.

Abstract translation: 本发明提供了一种测量晶状体的弹性的方法和用于测量晶状体的弹性的装置，用于测量晶状体1的刚度，其中晶状体1用脉冲激光照射以产生光弹性波 测量晶状体1的光弹性波和来自晶状体1的光弹性波。

公开(公告)号：US20140357969A1

公开(公告)日：2014-12-04

申请号：US14365609

申请日：2012-12-17

Applicant: RIKEN

Inventor： Satoshi Wada ,  Kazuo Tsubota ,  Atsushi Shinjo

IPC: A61B5/1455 ,  A61B5/145 ,  A61B3/12 ,  G01N21/65

CPC classification number: A61B5/1455 ,  A61B3/1025 ,  A61B3/12 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/14546 ,  G01N21/65 ,  G01N2021/5957 ,  G01N2021/653 ,  G01N2201/06113 ,  G01N2201/105

Abstract: In a laser scanning method for measuring in vivo substances, wavelength of the anti-Stokes line is made greater than wavelength absorption band of the specific substance, the wavelength of the probe light is shifted from the wavelength of the anti-Stokes line by a shift amount of Raman scattering of the specific substance, and the wavelength of the Stokes light is shifted from the wavelength of the probe light by the shift amount of the Raman scattering of the specific substance. According to this, density (concentration and distribution) of lutein in an eye fundus is measured quantitatively and non-invasively from a signal strength level of the anti-Stokes line.1

Abstract translation: 在用于体内物质测量的激光扫描方法中，反斯托克斯线的波长比特定物质的波长吸收带宽大，探针光的波长从反斯托克斯线的波长偏移了一个偏移 特定物质的拉曼散射量和斯托克斯光的波长从探测光的波长偏移特定物质的拉曼散射的偏移量。 据此，从反斯托克斯线的信号强度水平定量和非侵入地测量眼底中叶黄素的浓度（浓度和分布）。