公开(公告)号：WO0069421A3

公开(公告)日：2001-03-22

申请号：PCT/EP0004360

申请日：2000-05-16

Applicant: SANOL ARZNEI SCHWARZ GMBH ,  ARTH CHRISTOPH ,  MEESE CLAUS ,  SCHACHT DIETRICH WILHELM ,  WOLFF HANS MICHAEL

Inventor： ARTH CHRISTOPH ,  MEESE CLAUS ,  SCHACHT DIETRICH WILHELM ,  WOLFF HANS-MICHAEL

IPC: A61K9/14 ,  A61K9/70 ,  A61K31/135 ,  A61K31/137 ,  A61K47/14 ,  A61K47/32 ,  A61P13/10

CPC classification number: A61K9/7061 ,  A61K9/146 ,  A61K31/137

Abstract: The invention relates to a transdermal therapeutic system (TTS) for transcutaneously administering tolterodine over a period of several days and to a method for producing the same. The TTS contains a self-adhesive layer-shaped matrix material which contains a (meth)acrylate copolymer comprising ammonium groups. The TTS also contains at least one softener and up to 25 wt. % of tolterodine.

Abstract translation: 本发明涉及一种经皮治疗系统（TTS）为托特罗定的数天的皮施用和用于其生产的方法。 的TTS包含含有含铵基的（甲基）丙烯酸酯共聚物，至少一种增塑剂和至多25重量托特罗定的％自粘层形基体材料。

公开(公告)号：WO0010542A3

公开(公告)日：2000-05-04

申请号：PCT/DE9902636

申请日：1999-08-24

Applicant: ISIS PHARMA GMBH ,  SANOL ARZNEI SCHWARZ GMBH ,  KOENIG GERD ,  STOETER MICHAEL ,  BASSENGE EBERHARD ,  SCHACHT DIETRICH WILHELM

Inventor： STOETER MICHAEL ,  BASSENGE EBERHARD ,  SCHACHT DIETRICH WILHELM

IPC: A61K31/00 ,  A61K31/21 ,  A61K31/519 ,  A61P9/10

CPC classification number: A61K31/00

Abstract: The invention relates to the utilization of medicaments for producing heart/circulatory therapeutic agents with the simultaneous indication of phosphodiesterase inhibitors.

Abstract translation: 本发明涉及使用药物在制备心脏/循环疗法与Phophodiesterasehemmern同时指示。

公开(公告)号：DE102008060203A1

公开(公告)日：2010-06-10

申请号：DE102008060203

申请日：2008-12-07

Applicant: SCHACHT DIETRICH WILHELM

Inventor： SCHACHT DIETRICH WILHELM

IPC: A61L15/44 ,  A61K31/381

Abstract: Sheet-like device comprises: at least an oxidation sensitive active agent and/or its base or salt containing layer (5); an active agent impermeable backing layer (4); and a removable protective layer (6). The edge of the backing layer is permanently connected with the edge of the protective layer over the open sides of the active agent layer lying between the backing layer and the protective layer. The connection is a continuous sealing of the edge type, an encapsulation against environmental factors and provides permanent anaerobic micro-environment around the active substance particle. Independent claims are also included for: (1) producing the sheet-like device, comprising providing the backing layer, the protective layer, introducing the active agent layer between these layers, guiding the edges of the backing layer over the open sides of the active agent layer and applying on the corresponding edges of the protective layer and connecting the layers under continuous sealing of the edges; and (2) means for producing the sheet-like device by the above method, where the backing layer, the protective layer and the active agent containing layer are actable by two opposing rollers, which are heat regulated. ACTIVITY : Antiparkinsonian; Muscular-Gen; Antidepressant. No biological data given. MECHANISM OF ACTION : None given.