公开(公告)号：WO1994000602A1

公开(公告)日：1994-01-06

申请号：PCT/US1993006131

申请日：1993-06-28

Applicant: SENSOR TECHNOLOGIES, INC.

Inventor： SENSOR TECHNOLOGIES, INC. ,  CHICK, William, L. ,  WOLF, David, E. ,  CARDULLO, Richard, A.

IPC: C12Q01/68

CPC classification number: C12Q1/6818 ,  C12Q1/6825 ,  G01N33/52 ,  G01N33/582 ,  C12Q2565/107 ,  C12Q2563/107

Abstract: An in vivo method and apparatus for detecting an analyte in an individual. A sensor that includes a fluorescence reagent is placed in communication with the body fluids of the individual suspected of containing the analyte in such a way that once in place said sensor does not exit the skin of the individual. The sensor is configured to retain the fluorescence reagent while allowing analyte to diffuse into and out of said sensor. The sensor is illuminated transdermally, and the fluorescence from the fluorescence reagent associated with the presence of the analyte is measured.

Abstract translation: 用于检测个体中的分析物的体内方法和装置。 将包含荧光试剂的传感器放置成与怀疑含有分析物的个体的体液连通，使得一旦就位，所述传感器不会离开个体的皮肤。 传感器被配置为保持荧光试剂，同时允许分析物扩散进入和离开所述传感器。 传感器经皮照射，并测量与分析物存在相关的荧光试剂的荧光。

公开(公告)号：WO1991009312A1

公开(公告)日：1991-06-27

申请号：PCT/US1990007519

申请日：1990-12-14

Applicant: SENSOR TECHNOLOGIES, INC.

Inventor： SENSOR TECHNOLOGIES, INC. ,  CHICK, William, L. ,  WOLF, David, E. ,  CARDULLO, Richard, A

IPC: G01N33/566

CPC classification number: A61K49/0041 ,  A61K49/0004 ,  A61K49/0043 ,  A61K49/0052 ,  A61K49/0056 ,  G01N33/542 ,  G01N33/582 ,  G01N33/66 ,  G01N33/68 ,  Y10S436/805 ,  Y10S436/807 ,  Y10S436/815 ,  Y10T436/144444

Abstract: A method and device for the quantification of the concentration of glucose in blood and other body fluids, as well as samples derived from such fluids. The concentration of glucose being measured so as to enable a determination of the relative concentration of glucose in the sample to what is considered to be normal physiological limits. The device utilized in the measurement is a solid support to which is bound a member of a specific binding pair. Nonradioactive detection means are employed. A related device for in vivo testing is disclosed.

Abstract translation: 用于定量血液和其他体液中的葡萄糖浓度的方法和装置，以及来自这种流体的样品。 测量葡萄糖的浓度，以便能够将样品中葡萄糖的相对浓度确定为被认为是正常的生理极限。 在测量中使用的装置是固体支持物，其结合了特异性结合对的成员。 采用非放射性检测手段。 公开了用于体内测试的相关装置。