公开(公告)号：AU2003220293B2

公开(公告)日：2009-10-15

申请号：AU2003220293

申请日：2003-03-14

Applicant: SENSORS FOR MEDICINE AND SCIENCE INC

Inventor： KALIVRETENOS ARISTOTLE G ,  NIKOLAITCHIK ALEXANDRE V ,  DANILOFF GEORGE Y

IPC: C07F5/02 ,  C07F5/04 ,  G01N21/78 ,  G01N33/533 ,  G01N33/542 ,  G01N33/58 ,  G01N33/66

Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.

公开(公告)号：AU3078599A

公开(公告)日：1999-09-27

申请号：AU3078599

申请日：1999-03-11

Applicant: SENSORS FOR MEDICINE AND SCIENCE INC

Inventor： ULLMAN EDWIN F ,  NIKOLAITCHIK ALEXANDRE V ,  DANILOFF GEORGE Y ,  PARKER DAVID ,  COLVIN ARTHUR E JR ,  KALIVRETENOS ARISTOLE G

IPC: C07F5/00 ,  C07F5/02 ,  C09K11/06 ,  G01N21/78 ,  G01N33/58 ,  G01N33/66

Abstract: Compositions and methods for determining the presence or concentration of an analyte in a sample by exposing the sample to an indicator molecule comprising a fluorescent lanthanide metal chelate complex. The presence or concentration of the analyte in the sample is determined by observing and/or measuring the change in intensity of fluorescence emitted by the lanthanide metal chelate complex upon binding of the analyte to one or more recognition elements in the complex. The fluorescent indicator molecules can be used in various types of fluorescent sensing devices and are useful in various fields, including energy, medicine and agriculture.