公开(公告)号：US20210395307A1

公开(公告)日：2021-12-23

申请号：US17359370

申请日：2021-06-25

Applicant: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY

Inventor： PEIGEN REN ,  JIAN ZHANG ,  BIN TENG ,  JIAN LI ,  ZHENYU YAO

IPC: C07K7/08

Abstract: The present disclosure relates to a peptide for regulating fat metabolism and a method of regulating fat metabolism in an individual. The peptide is a variant of a SEQ ID NO: 2 having an amino acid sequence of YLYQWLGAPVPYPDPLEP, the variant comprises peptides selected from the group consisting of: (a) a first amino acid sequence consisting of the SEQ ID NO: 2, no more than 5 amino acids inserted to a C-terminal of the SEQ ID NO: 2, and no more than 5 amino acids inserted to a N-terminal of the SEQ ID NO: 2; (b) a second amino acid sequence consisting of a modified SEQ ID NO: 2; and (c) a third amino acid sequence consisting of at least 6 contiguous amino acids of the SEQ ID NO: 2 or the modified SEQ ID NO: 2.