公开(公告)号：EP1990627A4

公开(公告)日：2014-03-12

申请号：EP06714917

申请日：2006-02-28

Applicant: SHIMADZU CORP

Inventor： MORIYA NAOJI

IPC: G01N15/02 ,  G01N11/00 ,  G01N21/47

CPC classification number: G01N15/0211 ,  G01N21/4788 ,  G01N2011/008 ,  G01N2015/0216

公开(公告)号：EP2042852A4

公开(公告)日：2012-01-04

申请号：EP06781228

申请日：2006-07-19

Applicant: SHIMADZU CORP

Inventor： TSUNAZAWA YOSHIO ,  WADA YUKIHISA ,  MORIYA NAOJI ,  TAKUBO KENJI ,  TOTOKI SHINICHIRO ,  SHIMAOKA HARUO

IPC: G01N15/02 ,  B03C5/00 ,  B03C5/02 ,  G01N21/47

CPC classification number: G01N21/4788 ,  B03C5/005 ,  B03C5/026 ,  G01N2015/0003 ,  G01N2015/0038

公开(公告)号：EP2942616A4

公开(公告)日：2016-03-09

申请号：EP13869899

申请日：2013-12-25

Applicant: SHIMADZU CORP

Inventor： MURAMATSU TAKASHI ,  MORIYA NAOJI ,  MATSUDA NAOKI

IPC: G01N21/39 ,  G01J3/02 ,  G01N21/3504

CPC classification number: G01N21/39 ,  G01J3/027 ,  G01J3/10 ,  G01J3/42 ,  G01N21/3103 ,  G01N21/3504 ,  G01N2201/0612

公开(公告)号：EP1785718A4

公开(公告)日：2012-05-02

申请号：EP05766364

申请日：2005-07-15

Applicant: SHIMADZU CORP

Inventor： MORIYA NAOJI ,  TOTOKI SHINICHIRO ,  NAGUMO YUZO ,  WADA YUKIHISA ,  SAKAUCHI NAOFUMI ,  INOUE FUJIO ,  TAKEBE MASAHIRO

IPC: G01N15/02 ,  G01N21/47

CPC classification number: G01N21/4788 ,  G01N15/0211 ,  G01N15/0227 ,  G01N2013/003 ,  G01N2015/0038 ,  G01N2015/0294

公开(公告)号：JP2014106116A

公开(公告)日：2014-06-09

申请号：JP2012259243

申请日：2012-11-28

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： YAMAGUCHI TORU ,  MORIYA NAOJI

IPC: G01N21/35

CPC classification number: G01N21/3563 ,  G01J3/453

Abstract: PROBLEM TO BE SOLVED: To provide a plastic determination device achieving the improvement of accuracy of performing the determination of the kind of plastic on determined plastic having a deformed shape at a place which light is made enter.SOLUTION: In a Fourier transform infrared spectrophotometer 3, the light from a light source 7 is made enter determined plastic 33 via an incident optical system 29, and a detector 27 detects the light from the determined plastic 33 via a light-receiving optical system 31. A plastic determination device 1 determines the kind of the determined plastic 33 on the basis of a detection result of the Fourier transform infrared spectrophotometer 3. A focal distance of the incident optical system 29 is shorter than that of the light-receiving optical system 31.

Abstract translation: 要解决的问题：提供一种塑料测定装置，其在进入光的地方具有在具有变形形状的确定的塑料上进行塑料种类的确定的精度的提高。解决方案：在傅里叶变换红外分光光度计3 来自光源7的光通过入射光学系统29被制成确定的塑料33，并且检测器27经由光接收光学系统31检测来自确定的塑料33的光。塑料确定装置1确定种类 基于傅里叶变换红外分光光度计3的检测结果确定的塑料33。入射光学系统29的焦距比光接收光学系统31的焦距短。

公开(公告)号：JP2014044145A

公开(公告)日：2014-03-13

申请号：JP2012187360

申请日：2012-08-28

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： HATAKEBORI TAKAHIDE ,  MORIYA NAOJI ,  WADA YUKIHISA ,  NAKAMA YUJI

IPC: G01N21/05 ,  G01N21/27

CPC classification number: G01N21/05

Abstract: PROBLEM TO BE SOLVED: To provide a flow cell which enables flow cells having optical path lengths different from each other to be attached to one optical system without reducing light quantity in comparison with conventional one and causing problems in positional relationship on an optical axis and the like.SOLUTION: There is provided the flow cell in which a light introduction member for introducing measurement light into a linear capillary 1 where a sample solution is made to flow is attached to one end of the capillary 1, and a light leading out member which leads out light transmitted through the capillary 1 to the outside while transmitting the sample solution flowing in the capillary 1 is attached to the other end of the capillary 1. In the flow cell, the light introduction member comprises an optical waveguide 5 inserted into the capillary 1, and the light leading out member comprises a window member 8 attached to an opening at the other end of the capillary 1. Thus, flow cells 10 having different optical path lengths can be attached while loss of quantities of light transmitted through capillaries 1 is suppressed without causing the problem in positional relationship on an optical system of an absorbance detection device or the like.

Abstract translation: 要解决的问题：提供一种流通池，其使得具有彼此不同的光程长度的流通池相对于常规的流路连接到一个光学系统而不减少光量，并且在光轴上的位置关系和 提供了一种流式细胞，其中将测量光引入到其中使样品溶液流动的线性毛细管1中的光引入构件附接到毛细管1的一端，以及光导出构件， 将透过毛细管1的光引导到外部，同时透过在毛细管1中流动的样品溶液附着到毛细管1的另一端。在流动池中，光引入构件包括插入毛细管中的光波导5 如图1所示，光导出构件包括附接到毛细管1的另一端的开口的窗构件8 可以在不损害吸光度检测装置的光学系统的位置关系的问题的同时抑制通过毛细管1传输的光量的损失而附着不同的光程长度的光路10。

公开(公告)号：JP2012198062A

公开(公告)日：2012-10-18

申请号：JP2011061254

申请日：2011-03-18

Applicant: National Institute Of Advanced Industrial & Technology ,  Shimadzu Corp ,  株式会社島津製作所 ,  独立行政法人産業技術総合研究所

Inventor： HIRANO KEN ,  WADA YUKIHISA ,  MORIYA NAOJI ,  KAWABE TAKASHI

IPC: G01N33/543 ,  G01N33/53

Abstract: PROBLEM TO BE SOLVED: To provide a method for immobilizing nucleic acid having high immobilizing efficiency without using an amino group, having a simple immobilizing process and capable of forming a linker which is less susceptible to be degraded by a reagent included in a system to which immobilization nucleic acid is provided, and to provide a substrate with nucleic acid immobilized thereon which is acquired by using the method.SOLUTION: The method for immobilizing nucleic acid includes: constituting, on a substrate surface having a thiol group on the surface, a reaction system in which a linker reagent having two maleimide rings via a divalent organic group R, and the nucleic acid to be immobilized on the substrate surface and having the thiol group coexist; forming, in the reaction system, sulfide bonds between the thiol group on the substrate surface and one maleimide ring of the linker reagent, and between the other maleimide ring of the linker reagent and the thiol group of the nucleic acid; and providing a substrate with the nucleic acid immobilized thereon via the linker reagent.

Abstract translation: 待解决的问题：提供一种固定化具有高固定效率的核酸而不使用氨基的方法，其具有简单的固定化方法，并且能够形成不易被包含在其中的试剂降解的接头 系统，并且通过使用该方法获得固定有核酸的底物。 解决方案：用于固定核酸的方法包括：在表面具有硫醇基的底物表面上，构建其中具有通过二价有机基团R的具有两个马来酰亚胺环的接头试剂和核酸的反应体系 被固定在基板表面上并且具有硫醇基团共存; 在反应体系中形成底物表面上的硫醇基与接头试剂的一个马来酰亚胺之间的硫键与连接试剂的另一马来酰亚胺环与核酸的硫醇基之间的硫键; 并通过接头试剂提供其上固定有核酸的底物。 版权所有（C）2013，JPO＆INPIT

公开(公告)号：JP2007198818A

公开(公告)日：2007-08-09

申请号：JP2006015873

申请日：2006-01-25

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： WADA YUKIHISA ,  MORIYA NAOJI ,  NAGUMO YUZO

IPC: G01N15/02 ,  G01N21/01 ,  G01N21/47

Abstract: PROBLEM TO BE SOLVED: To provide a particle measuring instrument for acquiring diffusion information such as a diffusion coefficient.
SOLUTION: This particle measuring instrument is equipped with a cell 10 for holding a specimen, a power supply 15, electrodes 11 and 12 for forming a space-periodically changing electric field around the specimen in the cell by thereon impressing a voltage from the power supply 15, a light source 16 for applying measurement light to the specimen, a detector 18 for detecting diffracted light generated by applying the measurement light to the specimen with the periodic electric field formed around the specimen, an impressed-voltage control part 22a for causing the diffracted light to temporally change by stopping or modulating the voltage impressed on the electrodes from the power supply, and a signal analysis part 21 for analyzing information on the diffusion of particles based on the temporal change in the diffracted light detected by the detector 18. This measuring instrument is provided with a temperature control means 26 for adjusting the temperature of the specimen.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于获取扩散系数等扩散信息的粒子测量仪器。 解决方案：该粒子测量仪器配备有用于保持试样的电池单元10，电源15，电极11和12，用于通过在电池内施加电压来形成电池周围的试样周围的空间周期性变化的电场 电源15，用于向样本施加测量光的光源16，检测器18，用于检测通过在样本周围形成周期性电场而将测量光施加到样本而产生的衍射光，外加电压控制部22a 用于通过停止或调制从电源施加在电极上的电压来使衍射光瞬时变化;以及信号分析部分21，用于基于由检测器检测到的衍射光的时间变化来分析关于粒子扩散的信息 该测量仪器设有用于调节样本温度的温度控制装置26。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2007057338A

公开(公告)日：2007-03-08

申请号：JP2005241980

申请日：2005-08-24

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： WADA YUKIHISA ,  MORIYA NAOJI

IPC: G01N15/06 ,  G01N15/00 ,  G01N21/47

Abstract: PROBLEM TO BE SOLVED: To provide an optical measuring instrument for sensitively measuring information on particles in a liquid.
SOLUTION: This optical measuring instrument is equipped with: a light source 16; an electric source 15; a cell 10; a diffraction grating-cum-electrode 11 formed at a position adjoining a liquid specimen in a cell 11 for producing a basic diffracted light pattern by being illuminated with light from the light source 16; a voltage impression part 21 for changing particle distribution by impressing a voltage on the grating-cum-electrode 11 to produce a new derivative diffracted light pattern at an angular position different from that of the basic diffracted light pattern; a light detector group 25 for severally detecting derivative diffracted light of respective orders included in the derivative diffracted light pattern; and a derivative diffracted light signal processing part 31 for collecting respective signals of the derivative diffracted light simultaneously detected by the detector group 25. The processing part 31 measures information on the particles based on the sum of the plurality of substantially simultaneously collected signals of the derived diffracted light.
COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 要解决的问题：提供一种用于敏感地测量液体中的颗粒的信息的光学测量仪器。

解决方案：该光学测量仪器配备有：光源16; 电源15; 细胞10; 衍射光栅暨电极11，其形成在与单元11中的液体样本相邻的位置处，用于通过用来自光源16的光照射来产生基本衍射光图案; 用于通过在光栅暨电极11上施加电压来改变粒子分布的电压压印部分21，以在与基本衍射光图案不同的角度位置处产生新的衍生衍射光图案; 用于分别检测衍射衍射光图案中包括的各个阶的衍射衍射光的光检测器组25; 以及衍生衍射光信号处理部分31，用于收集由检测器组25同时检测的衍射衍射光的各个信号。处理部分31基于导出的多个基本同时收集的信号的和来测量关于粒子的信息 衍射光。 版权所有（C）2007，JPO＆INPIT

公开(公告)号：JP2006162408A

公开(公告)日：2006-06-22

申请号：JP2004353556

申请日：2004-12-07

Applicant: Shimadzu Corp ,  株式会社島津製作所

Inventor： WADA YUKIHISA ,  MORIYA NAOJI ,  WATANABE MASAYUKI

IPC: G01N21/47 ,  G01N15/00

Abstract: PROBLEM TO BE SOLVED: To provide an optical measuring instrument for measuring data related to particles contained in a liquid, such as a liquid electrolyte.
SOLUTION: The optical measuring instrument is equipped with a parallel inlet port group 15 for introducing second liquid into the first liquid in containers 11 in parallel so as to leave an equal interval between the second liquid, a light source 12 for emitting the incident light toward a lattice-like region, where the second liquid introduced from the parallel introducing port group 15 and the first liquid are alternately arranged in parallel and a detector 13 for detecting the diffracted lights emitted from the lattice-like region and constituted so as to measure the data related to the particles contained in either the first liquid or the second liquid, on the basis of the diffracted lights generated in the lattice-like region.
COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种用于测量与包含在诸如液体电解质的液体中的颗粒相关的数据的光学测量仪器。 解决方案：光学测量仪器配备有平行入口组15，用于将第二液体平行地引入容器11中的第一液体，以便在第二液体之间留有相等的间隔，用于发射第二液体的光源12 从平行导入口组15导入的第二液体和第一液体平行地交替排列的格子状区域的入射光和检测器13，用于检测从格子状区域射出的衍射光，构成为 基于在格子状区域中产生的衍射光来测量与包含在第一液体或第二液体中的颗粒有关的数据。 版权所有（C）2006，JPO＆NCIPI