公开(公告)号：US20250032392A1

公开(公告)日：2025-01-30

申请号：US18559989

申请日：2022-05-30

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Mika YOSHIMURA ,  Anna OKISHIMA ,  Takashi OKA ,  Hiroko SHIMIZU

IPC: A61K8/73 ,  A61Q19/00

Abstract: To provide a hyaluronate skin-penetrating cosmetic that allows a hyaluronate to penetrate into the skin without a complicated step such as composite formation of a hyaluronate.
A hyaluronate skin-penetrating cosmetic of the present disclosure contains a hyaluronate and an amphoteric surfactant.

公开(公告)号：US20220273545A1

公开(公告)日：2022-09-01

申请号：US17632131

申请日：2020-08-19

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Takashi OKA ,  Hiroko SHIMIZU ,  Mika YOSHIMURA

IPC: A61K8/73 ,  A61Q19/00 ,  A61K8/02

Abstract: There is provided a cosmetic comprising a hyaluronic acid particle, which can maintain a non-invasively excellent moisture retaining property over a long period of time.
A cosmetic of the present disclosure comprises an aqueous medium, and a hyaluronic acid particle dispersed in the aqueous medium, wherein the average particle diameter of the hyaluronic acid particle is 200 nm or less.

公开(公告)号：US20230321360A1

公开(公告)日：2023-10-12

申请号：US18043425

申请日：2021-09-28

Applicant: SHISEIDO COMPANY, LTD. ,  ASTI CORPORATION

Inventor： Takakazu OBANA ,  Hiroko SHIMIZU ,  Kazuyuki MIYAZAWA ,  Noriyuki OGAI ,  Yasuhiro TODA ,  Akinori INOH

IPC: A61M5/32 ,  A61M5/50

CPC classification number: A61M5/3204 ,  A61M2205/583 ,  A61M5/5086

Abstract: A needle-shaped projection-including part (1), which is configured to inject a liquid to a target object, the needle-shaped projection-including part including: a plate (111) in which a vertically penetrating discharge hole (114) is formed; one or a plurality of fine needle-shaped projections (112) that project from one face of the plate (111); and a lip portion (113) that is formed at an outer edge portion of the one face of the plate (111), wherein in response to pushing out of the liquid from the discharge hole (114), the liquid spreads in a space defined by the target object, the lip portion (113), and the one face of the plate (111), and the liquid enters the target object through holes formed by the one or plurality of needle-shaped projections (112).

公开(公告)号：US20240065962A1

公开(公告)日：2024-02-29

申请号：US18271521

申请日：2022-01-28

Applicant: Shiseido Company, Ltd.

Inventor： Anna OKISHIMA ,  Mika YOSHIMURA ,  Takashi OKA ,  Hiroko SHIMIZU

IPC: A61K8/73 ,  A61K8/19 ,  A61Q5/00 ,  A61Q19/00

CPC classification number: A61K8/735 ,  A61K8/19 ,  A61Q5/00 ,  A61Q19/00 ,  A61K2800/51 ,  A61K2800/546 ,  A61K2800/884

Abstract: To provide a cosmetic whose moisture-retaining property can be sufficiently secured even in cases where the cosmetic uses a hyaluronic acid compacted by neutralization of carboxyl groups of hyaluronic acid using a salt.
A cosmetic of the present disclosure comprises a first agent containing at least one salt selected from the group consisting of an inorganic salt and an organic acid salt, and hyaluronic acid; and a second agent for swelling the hyaluronic acid, the second agent containing a chelating agent.