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    1.
    发明专利
    未知

    公开(公告)号：DE10259820B4

    公开(公告)日：2006-05-24

    申请号：DE10259820

    申请日：2002-12-19

    Applicant: SIEMENS AG ,  INFINEON TECHNOLOGIES AG

    Inventor： GUMBRECHT WALTER ,  MUND KONRAD ,  SCHIENLE MEINRAD ,  THEWES ROLAND

    IPC: G01N33/50 ,  C12M1/00 ,  C12Q1/68 ,  G01N33/543

    Abstract: A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution applied to the spots. The microelectrode system has a pair of polarisation electrodes in order to produce an alternating electromagnetic field and a pair of sensor electrodes for measuring a voltage drop in the analyte.

    2.
    发明专利
    未知

    公开(公告)号：DE10259820A1

    公开(公告)日：2004-07-01

    申请号：DE10259820

    申请日：2002-12-19

    Applicant: SIEMENS AG ,  INFINEON TECHNOLOGIES AG

    Inventor： GUMBRECHT WALTER ,  MUND KONRAD ,  SCHIENLE MEINRAD ,  THEWES ROLAND

    IPC: C12Q1/68 ,  G01N33/543 ,  G01N33/50 ,  C12M1/00

    Abstract: A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution applied to the spots. The microelectrode system has a pair of polarisation electrodes in order to produce an alternating electromagnetic field and a pair of sensor electrodes for measuring a voltage drop in the analyte.

    DNA CHIP COMPRISING A MICROARRAY MADE OF MICROELECTRODE SYSTEMS
    3.
    发明专利
    DNA CHIP COMPRISING A MICROARRAY MADE OF MICROELECTRODE SYSTEMS 未知

    公开(公告)号：CA2510720C

    公开(公告)日：2012-02-14

    申请号：CA2510720

    申请日：2003-12-15

    Applicant: SIEMENS AG ,  INFINEON TECHNOLOGIES AG

    Inventor： SCHIENLE MEINRAD ,  THEWES ROLAND ,  GUMBRECHT WALTER ,  MUND KONRAD

    IPC: G01N33/543 ,  C12Q1/68

    Abstract: The invention relates to a DNA chip comprising a carrier (14) and a microarray of spots (1) containing immobilised catcher molecules which are arranged on said carrier. Each spot (1) contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution (38) applied to the spots (1). The microelectrode system has a pair of polarisation electrodes (2,4) in order to produce an alternating electromagnetic field and a pair of sensor electrodes (8,10) for measuring a voltage drop in the analyte (38).

    METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE/ENZYME COMPLEX OR OF AN ANALYTE/ENZYME CONJUGATE, ESPECIALLY FOR THE ELECTROCHEMICAL DETECTION OF THE ANALYTE, AND CORRESPONDING MEASURING DEVICE
    5.
    发明申请
    METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE/ENZYME COMPLEX OR OF AN ANALYTE/ENZYME CONJUGATE, ESPECIALLY FOR THE ELECTROCHEMICAL DETECTION OF THE ANALYTE, AND CORRESPONDING MEASURING DEVICE 审中-公开
    方法和系统确定浓度ANALYT酶复合物或ANALYT酶结合物，尤其是对于该电化学检测分析物，以及相关的测量装置

    公开(公告)号：WO2007014931A3

    公开(公告)日：2007-06-21

    申请号：PCT/EP2006064842

    申请日：2006-07-31

    Applicant: SIEMENS AG ,  BARLAG HEIKE ,  MUND KONRAD ,  GUMBRECHT WALTER

    Inventor： BARLAG HEIKE ,  MUND KONRAD ,  GUMBRECHT WALTER

    IPC: G01N33/543 ,  G01N27/49

    CPC classification number: C12Q1/001 ,  G01N27/3271 ,  Y10S435/817

    Abstract: The invention relates to a method for following the change in concentration of a redox-active substance, whereby suitable potentials for a reduction process or an oxidation process are applied to the working electrode of a measuring device. The invention is characterized in that the potential of the working electrode is pulsed and measuring phases and relaxation phases are alternately produced, the pulse lengths of measuring phase and relaxation phase being determined in a suitable manner. A rapid relaxation of the concentration gradient is electrochemically forced so that the measurement can be carried out on simple transducer arrays. A device for carrying out the method is characterized by comprising a transducer array (100, 200) in addition to a suitable potentiostat. The transducer array (100, 200) can consist of a planar metal substrate (1) on which at least one flexible insulator (2) is disposed, the metal surface and the insulator surface being firmly linked. The transducer array (200) can also comprise silicon-based CMOS structures.

    Abstract translation: 用于跟踪在用于还原过程的氧化还原活性物质合适的电位或氧化工艺的浓度变化可应用于的测量装置的工作电极。 根据本发明，工作电极的电势是脉冲和有交替地形成测量阶段和放松阶段，与测量相位和放松阶段的脉冲长度以合适的方式被设置。 因此，浓度梯度的快速弛豫以电化学方式进行，从而可以在简单的换能器阵列上进行测量。 在用于执行该方法的装置中，除了合适的恒电位仪之外还存在换能器阵列（100,200）。 换能器阵列（100）可以由平面金属衬底（1），其上至少一个柔性绝缘物（2）被布置成与金属表面和绝缘体表面之间的固定连接的。 换能器阵列（200）还可以包括硅基CMOS结构。

    METHOD FOR OPERATION OF A MICRO-FUEL CELL AND CORRESPONDING MICRO-FUEL CELL
    6.
    发明申请
    METHOD FOR OPERATION OF A MICRO-FUEL CELL AND CORRESPONDING MICRO-FUEL CELL 审中-公开
    一种用于操作微型燃料电池和燃料电池MICRO ZUGEHORIGE

    公开(公告)号：WO02084772A3

    公开(公告)日：2003-10-09

    申请号：PCT/DE0201426

    申请日：2002-04-17

    Applicant: SIEMENS AG ,  MUND KONRAD

    Inventor： MUND KONRAD

    IPC: H01M8/04186 ,  H01M8/08 ,  H01M8/22 ,  H01M8/04

    CPC classification number: H01M8/22 ,  H01M8/04186 ,  H01M8/08 ,  H01M8/222

    Abstract: Micro-fuel cells based on direct methanol fuel cells are known. According to the invention, a consumable material, comprising a mixture of a fluid fuel and an aqueous alkali liquor is supplied to the anode of the fuel cell, whilst the cathode is supplied with oxygen or air. A porous membrane (1) is arranged between the electrodes in the corresponding micro-fuel cell, whereby the porosity of the pores depends on the surface properties of the alkali liquor. Pore sizes are advantageously a diameter of

    Abstract translation: 基于直接甲醇燃料电池微型燃料电池是已知的。 根据本发明的燃料电池的阳极被供给液体燃料和含水的碱金属氢氧化物溶液作为消耗品的混合物，而阴极与氧气或空气供给。 在相关联的微型燃料电池是电极（2，3），其中，所述孔的孔隙率取决于碱性溶液的表面特性之间的多孔膜（1）。 有利的是，孔径大小，其直径<1微米。 对于消耗品，包括提供了一种可更换的墨盒（20）的浪费。

    METHOD FOR COLD STARTING FUEL CELLS OF A FUEL CELL FACILITY AND CORRESPONDING FUEL CELL FACILITY
    7.
    发明申请
    METHOD FOR COLD STARTING FUEL CELLS OF A FUEL CELL FACILITY AND CORRESPONDING FUEL CELL FACILITY 审中-公开
    方法燃料冷启动燃料电池系统及相关燃料电池系统

    公开(公告)号：WO0186745A3

    公开(公告)日：2003-02-13

    申请号：PCT/DE0101790

    申请日：2001-05-10

    Applicant: SIEMENS AG ,  GEBHARDT ULRICH ,  MUND KONRAD ,  WAIDHAS MANFRED

    Inventor： GEBHARDT ULRICH ,  MUND KONRAD ,  WAIDHAS MANFRED

    IPC: H01M8/04007 ,  H01M8/04014 ,  H01M8/04 ,  H01M8/02

    CPC classification number: H01M8/04067 ,  H01M8/04022

    Abstract: Cold starting is carried out by directly converting process gas into thermal energy by means of a catalytic reaction. The thermal energy is used to heat up the fuel cell stack, wherein the process of heating up the fuel cell stack is carried out separately from the operation of the fuel cell facility. To this end, heating elements (20, 40) form separate components in the fuel cell stack (10, 30), which are mounted in a predetermined order in said fuel cell stack (10, 30).

    Abstract translation: 冷起动时进行，所述工艺气体通过催化反应直接转化成热能，并且该热能用于加热燃料电池堆，被进行，其中加热来自所述燃料电池系统的操作分离出的燃料电池堆的方法。 到加热元件的该端部（10）（2）构成，其被布置在所述燃料电池堆的燃料电池堆（10），以预定的顺序单独的部件。

    METHOD FOR MEASURING THE CONCENTRATION OR CHANGE IN CONCENTRATION OF A REDOX-ACTIVE SUBSTANCE AND CORRESPONDING DEVICE
    10.
    发明申请
    METHOD FOR MEASURING THE CONCENTRATION OR CHANGE IN CONCENTRATION OF A REDOX-ACTIVE SUBSTANCE AND CORRESPONDING DEVICE 审中-公开
    用于测量还原性物质和相关装置的浓度或浓度变化的方法

    公开(公告)号：WO2005073708A3

    公开(公告)日：2005-10-27

    申请号：PCT/EP2005050333

    申请日：2005-01-26

    Applicant: SIEMENS AG ,  BARLAG HEIKE ,  GUMBRECHT WALTER ,  MUND KONRAD

    Inventor： BARLAG HEIKE ,  GUMBRECHT WALTER ,  MUND KONRAD

    IPC: C12Q1/00 ,  G01N27/49

    CPC classification number: G01N27/3277 ,  G01N2333/916 ,  Y10T436/143333

    Abstract: In order to follow the change in concentration of a redox-active substance, potential suitable for a reducing process or oxidation process are applied to the working electrode of a measuring device. According to the invention, the potential of the working electrode is pulsed and measuring phases and relaxation phases are alternately produced, the pulse lengths of the measuring phase and relaxation phase being predetermined in a suitable manner. In this manner, a rapid relaxation of the concentration gradient is forced electrochemically so that the measurement can be carried out on simple transducer arrays. The device for carrying out the inventive method comprises a transducer array in addition to a suitable potentiostat. Said transducer array may comprise a planar metal substrate (1) on which at least one flexible insulator (2) having a firm connection between the metal surface and the insulator surface is located. The array is generated by suitably structuring the substrate.

    Abstract translation: 为了追求氧化还原活性物质浓度的变化，对测量装置的工作电极施加用于还原过程或氧化过程的合适电位。 根据本发明，工作电极的电位被脉冲化并且交替地形成测量相位和松弛相位，测量相位和松弛相位的脉冲长度以适当的方式被预先确定。 因此，浓度梯度的快速弛豫以电化学方式进行，从而可以在简单的换能器阵列上进行测量。 在用于执行该方法的装置中，除了合适的恒电位仪之外还存在换能器阵列。 换能器阵列可以由平面金属基板（1）构成，在所述平面金属基板（1）上设置有至少一个具有金属表面和绝缘体表面的固定连接的柔性绝缘体（2）。 该数组是通过适当的结构创建的。

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