公开(公告)号：WO1994027493A1

公开(公告)日：1994-12-08

申请号：PCT/US1994005224

申请日：1994-05-11

Applicant: SOMANETICS CORPORATION

Inventor： SOMANETICS CORPORATION ,  LEWIS, Gary, D. ,  STODDART, Hugh, F.

IPC: A61B05/00

CPC classification number: A61B5/6814 ,  A61B5/14552 ,  A61B5/14553 ,  A61B2562/164

Abstract: A method and apparatus for spectrophotometrically determining internal physiological parameters such as blood constituents, wherein a source (132) of selected electromagnetic wavelenghts is disposed at a first location and at least two detectors (128, 130) are located at particular different distances from the source, selected such that both detectors receive energy that has traversed not only perimetral layers (114, 142, 214, 242, 314, 342) such as bone, tissue, etc. but also internal tissue (140, 240, 340) disposed beyond such perimetral layers, and one such detector (130) receives energy which has traversed only a small amount of the selected internal tissue while the other (128) receives energy which has traversed substantially more of such tissue, whereby comparative analysis of the data from the two detectors provides information which consistently characterizes only the selected internal tissue. In cerebral oximetry, where the detector and receivers are applied to the forehead, the particular distances from the source to the two detectors are about 30 and 40 mm., respectively.

Abstract translation: 一种用于分光光度测定内部生理参数（如血液成分）的方法和装置，其中所选择的电磁波长的源极（132）设置在第一位置处，并且至少两个检测器（128,130）位于离源极特别不同的距离处 被选择为使得两个检测器接收不仅穿过周边层（114,142,214,242,314,342）的能量，所述周边层（114,142,214,242,314,342）例如骨，组织等，而且还包括设置在该外部层之外的内部组织（140,240,340） 周边层，并且一个这样的检测器（130）接收仅穿过少量所选择的内部组织的能量，而另一个（128）接收到已经穿过该组织的实质上更多的能量，由此对来自两个 检测器提供的信息始终只表示所选择的内部组织。 在脑血氧测定法中，检测器和接收器应用于前额，从源到两个检测器的特定距离分别为30和40 mm。

公开(公告)号：WO1992021280A1

公开(公告)日：1992-12-10

申请号：PCT/US1992004743

申请日：1992-06-04

Applicant: SOMANETICS CORPORATION

Inventor： SOMANETICS CORPORATION ,  LEWIS, Gary, D. ,  KLOSE, Peter, H. ,  MESSING, Wayne, P.

IPC: A61B03/00

CPC classification number: A61B5/6814 ,  A61B5/0091 ,  A61B5/02433 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/4312

Abstract: A thin, lightweight optical source/receiver unit (12) adapted for application to the human forehead, for use in a cerebral oximeter, has a source of electromagnetic radiation of selected wavelengths (36) (e.g., light in the near infrared range) at a first position and a pair of sensors located at particular and differing distances from the source. The source may comprise light-emitting diodes (36a-36b) and the detectors may comprise photosensors (32, 34), all of which are preferably mounted on a small and flexible printed circuit strip (30). Electromagnetic shielding (42) substantially surrounds the source and detectors as well as the adjacent electrical conductors associated with each. The shielded printed circuit (30) and components are housed within layers of thin flexible material, of which the layer that contacts the patient preferably comprises soft, light-absorbing open-celled foam material (26) which is transmissible by water vapor, to dissipate moisture at the patient-sensor interface.

Abstract translation: 适于应用于人类前额的用于脑血氧计的薄而轻的光源/接收器单元（12）具有选定波长（36）（例如，近红外范围内的光）的电磁辐射源 第一位置和一对传感器，其位于离源的特定且不同的距离处。 源可以包括发光二极管（36a-36b），并且检测器可以包括光电传感器（32,34），它们都优选地安装在小而柔性的印刷电路板（30）上。 电磁屏蔽（42）基本上围绕源和检测器以及与每个相关联的相邻电导体。 屏蔽印刷电路（30）和部件容纳在薄柔性材料层内，其中接触患者的层优选地包括柔软的，光吸收的开放泡沫泡沫材料（26），其通过水蒸气传播，以消散 患者 - 传感器界面处的湿气。

公开(公告)号：WO1996011626A1

公开(公告)日：1996-04-25

申请号：PCT/US1995012806

申请日：1995-10-16

Applicant: SOMANETICS CORPORATION

Inventor： SOMANETICS CORPORATION ,  LEWIS, Gary, D. ,  MESSING, Wayne, P. ,  GONOPOLSKIY, Oleg ,  SCHEUING, Richard, S.

IPC: A61B05/00

CPC classification number: A61B5/14553 ,  A61B5/7217 ,  A61B2562/182

Abstract: The invention relates to methods and apparatus for improving the signal quality, and hence the operational accuracy, of clinical biomedical spectrophotometric apparatus such as oximeters, in which wavelength-specific light is applied to a test subject at one point and resultant light intensity is detected at another such point after passing through a given volume of the test subject tissue and/or other biological substance within the particular such volume involved.

Abstract translation: 本发明涉及用于改善临床生物医学分光光度仪器如血氧仪的信号质量的方法和装置，并且因此其操作精度在波长特异性光被施加到测试对象在一点上并且得到的光强度被检测到 在通过特定体积的所述测试对象组织和/或所涉及的特定体积内的其他生物物质之间的另一个这样的点。

公开(公告)号：WO1992021283A1

公开(公告)日：1992-12-10

申请号：PCT/US1992004654

申请日：1992-06-04

Applicant: SOMANETICS CORPORATION

Inventor： SOMANETICS CORPORATION ,  LEWIS, Gary, D. ,  MESSING, Wayne, P. ,  STEWART, Melville, C., II

IPC: A61B05/00

CPC classification number: A61B5/14552 ,  A61B5/02433 ,  A61B5/14553 ,  A61B5/4064

Abstract: A cerebral oximeter for use with a sensor unit (12) applied to the forehead of a patient, or other such selected cranial area, whihc emits selected wavelengths of electromagnetic radiation (e.g. light in the near infrared range) that passes through a selected volume of brain tissue inside the patient's skull. The emitted wavelengths are selectively absorbed by the blood within the irradiated brain tissues, present in arterial, venous, capillary, and/or other supply, and the resulting radiation is detected and analyzed by a computer (20) to determine the hemoglobin oxygen saturation of the composite blood supply within the selected volume of brain tissue, with readout provided as a quantified particular value (e.g., a number representing the instantaneous value measured), and/or also in graphical or other time-representative display, as for example on the CRT monitor (22) of the computer, with attendant storage of digital values for record purposes or other subsequent use.

Abstract translation: 用于与应用于患者或其他这样选择的颅区的前额的传感器单元（12）一起使用的脑血氧计，其发射选定波长的电磁辐射（例如在近红外范围的光），所述电磁辐射通过选定体积的 患者头骨内的脑组织。 所发射的波长被照射的脑组织中存在于动脉，静脉，毛细管和/或其他电源中的血液选择性吸收，并且由计算机（20）检测和分析所得到的辐射，以确定血红蛋白氧饱和度 在所选择的脑组织体积内的复合血液供应，其中提供作为量化的特定值（例如，表示所测量的瞬时值的数量）的读数，和/或图形或其它时间有代表性的显示，例如在 计算机的CRT显示器（22），随附的数字值存储用于记录目的或其他后续使用。

公开(公告)号：EP0700267A1

公开(公告)日：1996-03-13

申请号：EP94917948.0

申请日：1994-05-11

Applicant: SOMANETICS CORPORATION

Inventor： LEWIS, Gary, D. ,  STODDART, Hugh, F.

IPC: A61B5

CPC classification number: A61B5/6814 ,  A61B5/14552 ,  A61B5/14553 ,  A61B2562/164

Abstract: A method and apparatus for spectrophotometrically determining internal physiological parameters such as blood constituents, wherein a source (132) of selected electromagnetic wavelenghts is disposed at a first location and at least two detectors (128, 130) are located at particular different distances from the source, selected such that both detectors receive energy that has traversed not only perimetral layers (114, 142, 214, 242, 314, 342) such as bone, tissue, etc. but also internal tissue (140, 240, 340) disposed beyond such perimetral layers, and one such detector (130) receives energy which has traversed only a small amount of the selected internal tissue while the other (128) receives energy which has traversed substantially more of such tissue, whereby comparative analysis of the data from the two detectors provides information which consistently characterizes only the selected internal tissue. In cerebral oximetry, where the detector and receivers are applied to the forehead, the particular distances from the source to the two detectors are about 30 and 40 mm., respectively.

公开(公告)号：EP0597875A1

公开(公告)日：1994-05-25

申请号：EP92913850.0

申请日：1992-06-04

Applicant: SOMANETICS CORPORATION

Inventor： LEWIS, Gary, D. ,  MESSING, Wayne, P. ,  STEWART, Melville, C., II

IPC: A61B5

CPC classification number: A61B5/14552 ,  A61B5/02433 ,  A61B5/14553 ,  A61B5/4064

Abstract: Oxymètre cérébral destiné à être utilisé avec un capteur (12) appuyé sur le front d'un patient, ou une autre zone cranienne sélectionnée, émettant des longueurs d'ondes sélectionnées de rayonnement électromagnétique (par exemple, de la lumière de la plage de l'infrarouge) passant à travers un volume sélectionné de tissu du cerveau, à l'intérieur du crâne du patient. Les longueurs d'ondes émises sont sélectivement absorbées par le sang se trouvant à l'intérieur du tissu du cerveau irradié, présent dans l'apport artériel, véneux, capilaire et/ou autre, et le rayonnement résultant est détecté puis analysé par un ordinateur (20) afin de déterminer la saturation en oxygène de l'hémoglobine de l'apport de sang composite dans le volume sélectionné de tissu du cerveau, avec un affichage se présentant sous la forme d'une valeur particulière quantifiée (par exemple, un nombre représentant la valeur instantanée mesurée), et/ou également dans un affichage graphique ou temporel, par exemple sur le moniteur à écran cathodique (22) de l'ordinateur, les valeurs numériques étant stockées à des fins d'enregistrement ou d'utilisation ultérieure.