公开(公告)号：WO2013105485A4

公开(公告)日：2013-10-31

申请号：PCT/JP2013000019

申请日：2013-01-08

Applicant: SONY CORP

Inventor： TANAKA EIICHI ,  TAMAI MASANOBU ,  MORIKAWA HIROAKI ,  TATSUTA HIROKAZU ,  DOWAKI SUGURU ,  HAYAKAWA TOMOHIRO ,  MATSUI ERIKO ,  HASEGAWA SHIN ,  MINAKAWA TATSUYA

IPC: G01N35/00

CPC classification number: G06T7/0016 ,  G01N35/00603 ,  G01N35/0099 ,  G06T7/20 ,  G06T2207/10056 ,  G06T2207/30004

Abstract: There is provided a measurement apparatus including an objective lens, a stage, a setting unit, and a controller. The stage is configured to support a sample vessel in which a plurality of wells each containing a sample are arranged and to define relative positions of the sample vessel and the objective lens. The setting unit is configured to determine whether to set each of the plurality of wells to be a measurement target and set the measurement target. The controller is configured to control the stage such that a well determined to be the measurement target by the setting unit and the objective lens face each other.

Abstract translation: 提供了一种包括物镜，台，设定单元和控制器的测量装置。 该台被构造成支撑样品容器，在该样品容器中布置了各自包含样品的多个孔并且限定样品容器和物镜的相对位置。 设定单元被配置为确定是否将多个井中的每一个井设置为测量目标并设置测量目标。 控制器被配置为控制台使得由设置单元和物镜确定为测量目标的阱彼此面对。

公开(公告)号：JP2013145318A

公开(公告)日：2013-07-25

申请号：JP2012005682

申请日：2012-01-13

Applicant: Sony Corp ,  ソニー株式会社

Inventor： TANAKA HIDEKAZU ,  TAMAI MASANOBU ,  MORIKAWA HIROAKI ,  TATSUTA HIROKAZU ,  DOWAKI MASARU ,  HAYAKAWA TOMOHIRO ,  MATSUI ERIKO ,  HASEGAWA MAKOTO ,  MINAGAWA TATSUYA

IPC: G02B21/26 ,  C12M1/34 ,  G02B21/36

CPC classification number: G06T7/0016 ,  G01N35/00603 ,  G01N35/0099 ,  G06T7/20 ,  G06T2207/10056 ,  G06T2207/30004

Abstract: PROBLEM TO BE SOLVED: To provide a measurement apparatus, a program, and a measurement method that are suitable for measurement of samples contained in a plurality of wells over a predetermined period of time by using a microscope.SOLUTION: There is provided a measurement apparatus including an objective lens, a stage, a setting unit, and a controller. The stage is configured to support a sample vessel in which a plurality of wells each containing a sample are arranged and to define relative positions of the sample vessel and the objective lens. The setting unit is configured to determine whether to set each of the plurality of wells to be a measurement target. The controller is configured to control the stage such that a well determined to be the measurement target by the setting unit and the objective lens face each other.

Abstract translation: 要解决的问题：提供一种适用于通过使用显微镜在预定时间段内测量包含在多个孔中的样品的测量装置，程序和测量方法。解决方案：提供了一种测量装置 包括物镜，舞台，设定单元和控制器。 该台被配置为支撑其中布置有多个包含样品的孔并且限定样品容器和物镜的相对位置的样品容器。 设置单元被配置为确定是否将多个井中的每一个设置为测量目标。 控制器被配置为控制台，使得由设定单元和物镜彼此面对的被确定为测量目标的井。

公开(公告)号：JP2006261961A

公开(公告)日：2006-09-28

申请号：JP2005075498

申请日：2005-03-16

Applicant: Sony Corp ,  ソニー株式会社

Inventor： TAMAI MASANOBU

IPC: G01B11/30 ,  G01N21/84 ,  H04N5/225 ,  H04N5/335 ,  H04N5/349 ,  H04N5/361 ,  H04N5/369 ,  H04N5/372 ,  H04N5/374 ,  H04N17/00

Abstract: PROBLEM TO BE SOLVED: To enable a still image pickup device to be speedily moved to the image pickup place of an object at the time of picking up a still image. SOLUTION: The still image pickup device includes: an XY table 26 having the image pickup device 25 for dividing and picking up the still image; an X axis shaft 35 passing through the XY table 26 to move the XY table 26 in an X axis direction; a Y axis shaft 45 passing through the XY table 26 off the X axis shaft 35 in a Y axis direction orthogonal to the X axis direction to move the XY table 26 in the Y axis direction; a friction reducing member connecting the XY table 26 and the first and Y axis shaft 45 to smoothly move the XY table 26; and an image processing part for applying a prescribed image processing to the still image divided and picked up by the image pickup device 25. Thus, the image pickup device 25 can be moved at a high speed in X and Y directions and the still image of a wide viewing angle is obtained. COPYRIGHT: (C)2006,JPO&NCIPI

Abstract translation: 要解决的问题：为了使拍摄静止图像时的静止图像拾取装置能够快速地移动到对象的图像拾取位置。 解决方案：静止图像拾取装置包括：具有用于分割和拾取静止图像的图像拾取装置25的XY工作台26; X轴轴35穿过XY工作台26，以使XY工作台26沿X轴方向移动; Y轴轴45，其沿与X轴方向正交的Y轴方向穿过XY台26离开X轴轴35，以使XY工作台26沿Y轴方向移动; 连接XY工作台26和第一和Y轴轴45以平滑地移动XY工作台26的摩擦减小构件; 以及图像处理部分，用于对由图像拾取装置25分离和拾取的静止图像应用规定的图像处理。因此，图像拾取装置25可以在X和Y方向上以高速移动，并且静止图像 获得宽视角。 版权所有（C）2006，JPO＆NCIPI

公开(公告)号：JP2004012200A

公开(公告)日：2004-01-15

申请号：JP2002163436

申请日：2002-06-04

Applicant: SONY CORP

Inventor： SHINOHARA YASUO ,  TANAKA MINORU ,  KATAGAI KENICHI ,  MIYAZAWA TATSUO ,  TAMAI MASANOBU

IPC: G01N23/04 ,  G21K5/02 ,  G21K5/10

Abstract: PROBLEM TO BE SOLVED: To provide an X-ray tomograph for adjusting a location of an object to be tested in the direction other than rotational and vertical directions of a rotation table while X rays are radiated, identifying an observed region of the tested object, picking up a projected image of the object to be tested as a position after a location adjustment is maintained and having a micromotion means for not influencing concentricity of an air bearing if the air bearing is used for a rotation base. SOLUTION: The X-ray tomograph is provided with the rotation base for mounting the object to be tested 7 between an X-ray source and a two-dimensional detection means for picking up the projected image of the tested object and having a rotational axis perpendicular to a normal from an X-ray focus to a light receiving face of the two-dimensional detection means; a vertical direction micromotion mechanism for adjusting a location of the rotation base in the vertical direction. The micromotion means 9 has a horizontal direction micromotion location adjustment mechanism for adjusting a location of the rotation base on a surface perpendicular to the rotational axis. While the rotation base rotates and the projected image of the object to be tested 7 is picked up, a drive source 13 of the micromotion means 9 is wholly isolated from the rotation base. COPYRIGHT: (C)2004,JPO

公开(公告)号：JP2009222646A

公开(公告)日：2009-10-01

申请号：JP2008069240

申请日：2008-03-18

Applicant: Sony Corp ,  ソニー株式会社

Inventor： TAMAI MASANOBU

IPC: G01M11/00

Abstract: PROBLEM TO BE SOLVED: To provide optical characteristic measurement equipment for improving the measurement accuracy by allowing two-dimensional measurement, in the optical characteristic measurement of a planar optical system.
SOLUTION: This optical characteristic measurement equipment is equipped with: a light receiving system 4 for condensing light from the planar optical system 1 and reflecting it in a predetermined direction; a photodetector 5 for inputting the reflected light from the light receiving system 4; and an arithmetic apparatus 3 for calculating a characteristic value of the optical system 1, based on the output signal of the photodetector 5. The light receiving system 4 has a reflector 4B formed by arranging a plurality of individually drivable light reflecting elements M. The arithmetic apparatus 3 applies sine wave to a driving signal of the light reflecting elements M, and calculates the characteristic value of the optical system 1 by a heterodyne method based on the output signal of the photodetector 5. Two-dimensional measurement is thus allowed, a highly sensitive measurement is performed even with feeble light, and the measurement accuracy is improved.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：在平面光学系统的光学特性测量中，提供通过允许二维测量来提高测量精度的光学特性测量设备。 该光学特性测量设备配备有：用于聚集来自平面光学系统1的光并沿预定方向反射的光接收系统4; 用于输入来自光接收系统4的反射光的光电检测器5; 以及用于基于光电检测器5的输出信号计算光学系统1的特征值的运算装置3.光接收系统4具有通过布置多个可独立驱动的光反射元件M而形成的反射器4B。算术 装置3将正弦波应用于光反射元件M的驱动信号，并且通过基于光电检测器5的输出信号的外差法来计算光学系统1的特性值。因此允许二维测量，高度 甚至在微弱的光线下进行敏感测量，并提高测量精度。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2005037193A

公开(公告)日：2005-02-10

申请号：JP2003198643

申请日：2003-07-17

Applicant: Sony Corp ,  ソニー株式会社

Inventor： MIYAZAWA TATSUO ,  TANAKA MINORU ,  SHINOHARA YASUO ,  KATAGAI KENICHI ,  TAMAI MASANOBU

IPC: G01N23/04 ,  G01T1/00

Abstract: PROBLEM TO BE SOLVED: To propose an imaging technique for computerized tomography, which rapidly computes the optimal parameter used in a reconstruction computation process for internal structure data of a body to be inspected and can obtain the internal structure data with high sharpness by using the parameter.
SOLUTION: The system is provided with an X-ray source, a two-dimensional detecting means and a rotatable base section for the inspected body disposed between the X-ray source and the detecting means. The internal structure data are reconstructed from the projection images of the inspected body obtained at every angular displacement, and pixel data on a line perpendicular to the axis of the rotation of the inspected body are read from the projection images of the respective angular displacements, and an offset value of the rotation axis of the inspected body from the perpendicular line, which is dropped from the X-ray focal point to the detecting means, is set as the parameter used in the reconstruction computation process, and the pixel data at respective angular displacements are subjected to the reconstruction computation process while changing the parameter to obtain a plurality of images, and sharpness values are calculated respectively. When the maximum sharpness value is detected, the value of the parameter is specified as the optimal offset value of the rotation axis, and the internal structure data of the inspected body are reconstructed in consideration of the optimal offset value of the rotation axis.
COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 要解决的问题：提出一种用于计算机断层摄影的成像技术，其快速计算用于待检查身体的内部结构数据的重建计算过程中的最佳参数，并且可以通过以下方式获得具有高锐度的内部结构数据 使用参数。 解决方案：系统设置有X射线源，二维检测装置和设置在X射线源和检测装置之间的被检查体的可旋转基座部分。 从每个角位移获得的被检查体的投影图像重建内部结构数据，并且从相应的角位移的投影图像中读取与被检查体的旋转轴线垂直的线上的像素数据，以及 被检体的从X射线焦点下降到检测机构的垂直线的旋转轴的偏移值被设定为在重建计算处理中使用的参数，并且各个角度的像素数据 在改变参数以获得多个图像的同时对位移进行重构计算处理，并且分别计算清晰度值。 当检测到最大清晰度值时，将参数的值指定为旋转轴的最佳偏移值，并且考虑到旋转轴的最佳偏移值来重建检查体的内部结构数据。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2004340630A

公开(公告)日：2004-12-02

申请号：JP2003134974

申请日：2003-05-13

Applicant: Sony Corp ,  ソニー株式会社

Inventor： MIYAZAWA TATSUO ,  TANAKA MINORU ,  SHINOHARA YASUO ,  KATAGAI KENICHI ,  TAMAI MASANOBU

IPC: G01N23/04

Abstract: PROBLEM TO BE SOLVED: To remove an influence of a change with the lapse of time of a focal position in a radiation such as an X-ray emitted to a specimen, by simple constitution, and to enhance fineness of an internal structure data calculated by reconstitution calculation. SOLUTION: In this computer tomography having a radiation source 1, a two-dimensional detection means 2 for picking up a projection image of the specimen 7, and a rotary base part arranged between the radiation source 1 and the two-dimensional detection means 2, and for mounting the specimen 7 to be rotated at a prescribed angle displacement, to reconstitute the internal structure data, based on the projection image of the specimen 7 image-picked up in every angle displacement, the focal position in an optional time of the radiation is set as a reference focal position, the focal position after the lapse of a prescribed time is detected after setting the reference focal position, a variation between the reference focal position and the focal position after the lapse of the prescribed time is calculated, and a positional relation between the radiation 1, and the specimen 7 and the two-dimensional detection means 2 is moved based on the variation. COPYRIGHT: (C)2005,JPO&NCIPI

公开(公告)号：JP2005134213A

公开(公告)日：2005-05-26

申请号：JP2003369394

申请日：2003-10-29

Applicant: Sony Corp ,  ソニー株式会社

Inventor： KATAGAI KENICHI ,  TANAKA MINORU ,  SHINOHARA YASUO ,  MIYAZAWA TATSUO ,  TAMAI MASANOBU

IPC: G01N23/04

Abstract: PROBLEM TO BE SOLVED: To acquire a projection image having a high resolution, for example, a fourfold resolution compared with hitherto, without changing a magnification of an X-ray two-dimensional detector as it is.
SOLUTION: When imaging a transmitted X-ray by using a two-dimensional detection means by irradiating an inspection object with the X-ray and reconstituting internal structure data of the inspection object from projection images of the inspection object imaged at each angle deformation, the inspection object is irradiated with the X-ray and the first projection image 31 is imaged by the two-dimensional detection means on the ordinary position, and the second projection image 32 of the inspection object is imaged after moving the two-dimensional detection means as much as a half pixel portion in the vertical and lateral direction from the ordinary position. Then, the first and second projection images 31, 32 imaged at each angle deformation are converted into the first and second enlarged projection images having a prescribed resolution respectively, and the first and second enlarged projection images are composed together at each angle deformation to form a composite enlarged projection image, and the internal structure data of the inspection object is reconstituted from the composite enlarged projection image at each angle deformation.
COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 要解决的问题：与迄今为止相比，获得具有高分辨率的投影图像，例如，不改变X射线二维检测器的倍率。 解决方案：通过使用二维检测装置对检测对象进行X射线照射并且将检查对象的内部结构数据从投影图像以每个角度成像的投影图像重新构成而成像透射的X射线 变形时，利用X射线对检查对象进行照射，并且通过二维检测装置对普通位置对第一投影图像31进行成像，并且检测对象的第二投影图像32在移动二维 检测装置在垂直方向和横向上距离普通位置多达半个像素部分。 然后，以每个角度变形成像的第一和第二投影图像31,32分别被转换成具有规定分辨率的第一和第二放大投影图像，并且第一和第二放大投影图像在每个角度变形处一起组合以形成 复合放大投影图像，并且检查对象的内部结构数据在每个角度变形时从复合放大投影图像重构。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2005037158A

公开(公告)日：2005-02-10

申请号：JP2003197383

申请日：2003-07-15

Applicant: Sony Corp ,  ソニー株式会社

Inventor： MIYAZAWA TATSUO ,  TANAKA MINORU ,  SHINOHARA YASUO ,  KATAGAI KENICHI ,  TAMAI MASANOBU ,  TSUTSUI AKIKO

IPC: G01N23/04 ,  G01T1/00

Abstract: PROBLEM TO BE SOLVED: To provide an imaging method and its system for computerized tomography, capable of acquiring internal structure data of a body to be inspected at a higher rate of magnification. SOLUTION: The system is provided with an X-ray source, a two-dimensional detecting means which makes a transmitted X-ray projection image of the inspected body, and a rotatable base section on which the inspected body disposed between the X-ray source and the two-dimensional detecting means is mounted and which rotates at a prescribed angular displacement. By using the system, the internal structure data is reconstructed from the projection image of the inspected body photographed at every angular displacement. Positional and angular relations between the rotatable base section and the two-dimensional detecting means are adjusted so that a portion of the inspected body is projected onto the two-dimensional detecting means, and the portion of the inspected body is photographed to obtain a group of partial projection images. Then, the positional and angular relations between the rotatable base section and the two-dimensional detecting means are adjusted so that the remaining portion of the inspected body is projected onto the two-dimensional detecting means, and the remaining portion of the inspected body is photographed to obtain another group of partial projection images. The magnified internal structure data of the inspected body are computed from these groups of the partial projection images. COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 要解决的问题：提供一种用于计算机断层摄影的成像方法及其系统，能够以更高的倍率获取要检查的身体的内部结构数据。 解决方案：该系统设置有X射线源，二维检测装置，其构成检查体的透射X射线投影图像，以及可旋转的基部，被检体位于其上，X 并且二维检测装置被安装并以规定的角位移旋转。 通过使用该系统，从每个角位移拍摄的被检体的投影图像重建内部结构数据。 调整可旋转基部与二维检测装置之间的位置和角度关系，使得被检查体的一部分投影到二维检测装置上，并且检查被检体的部分，以获得一组 部分投影图像。 然后，调整可旋转基部与二维检测装置之间的位置和角度关系，使得被检查体的剩余部分投射到二维检测装置上，并且检查被检体的剩余部分 以获得另一组部分投影图像。 从这些组的部分投影图像计算被检体的放大的内部结构数据。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2003344311A

公开(公告)日：2003-12-03

申请号：JP2002152656

申请日：2002-05-27

Applicant: Sony Corp ,  ソニー株式会社

Inventor： TANAKA MINORU ,  SHINOHARA YASUO ,  KATAGAI KENICHI ,  TAMAI MASANOBU ,  MIYAZAWA TATSUO

IPC: G01N23/04

Abstract: PROBLEM TO BE SOLVED: To provide an X-ray tomographic method and an X-ray tomographic apparatus in which the influence by a fluctuation in X-rays for irradiating a subject from an X-ray source is removed, and in which the definition of internal structure data is enhanced by a reconstitution calculation on the basis of a projection image. SOLUTION: The X-ray tomographic apparatus has the X-ray source 1; a rotary base 3 on which the specimen is placed between the X-ray source 1 and a two-dimensional detection means 2 used to image the projection image of the specimen, which is provided with a shaft at right angles to a perpendicular lowered from an X-ray focal point to a light receiving face of the two-dimensional detection means 2, and which is turned at an angle displacement pitch based on a setting operation; a projection-image storage means 23 used to store the projection image of the specimen imaged at each angle displacement; a reconstitution means 24 used to reconstitute the internal structure data on the basis of the projection image; and a display means 25 used to display the reconstituted internal structure data. A difference between respective projection images imaged due to the change with time of the X-rays emitted from the X-ray source 1 is detected, the projection images are corrected by a difference amount portion before the reconstitution calculation, and the difference between the respective projection images is detected on the basis of a reference image imaged at a reference angle phase and on the basis of a projection image imaged at the same angle phase as the reference image. COPYRIGHT: (C)2004,JPO

Abstract translation: 要解决的问题：提供一种X射线断层摄影方法和X射线断层摄影装置，其中除去用于从X射线源照射被摄体的X射线的波动的影响，其中 通过基于投影图像的重构计算来增强内部结构数据的定义。 解决方案：X射线断层摄影装置具有X射线源1; 旋转基座3，其上放置有X射线源1和用于对样本的投影图像进行成像的二维检测装置2之间的试样，该检测装置设置有与垂直于 X射线焦点指向二维检测装置2的光接收面，并且基于设定操作以角度位移间距转动; 投影图像存储装置23，用于存储在每个角位移处成像的标本的投影图像; 用于基于投影图像重建内部结构数据的重构装置24; 以及用于显示重构的内部结构数据的显示装置25。 检测由于从X射线源1发射的X射线随时间的变化而成像的各个投影图像之间的差异，投影图像由重新计算之前的差量部分校正，并且各个 基于以参考角度相位成像的参考图像，并且以与参考图像相同的角度相位成像的投影图像来检测投影图像。 版权所有（C）2004，JPO