SURFACE ENHANCED RAMAN SPECTROSCOPY DETECTION WITH ION SEPARATION PRE-FILTER
    3.
    发明申请
    SURFACE ENHANCED RAMAN SPECTROSCOPY DETECTION WITH ION SEPARATION PRE-FILTER 审中-公开
    表面增强拉曼光谱检测与离子分离预过滤器

    公开(公告)号:WO2008085357A2

    公开(公告)日:2008-07-17

    申请号:PCT/US2007/025929

    申请日:2007-12-17

    CPC classification number: G01N21/658 H01J49/004

    Abstract: Detecting and identifying ions using surface enhanced Raman spectroscopy (SERS) and an ion separation pre-filter, such as an ion spectrometer, are provided. The combination of an ion separator as a pre-filter for SERS provides a highly sensitive detector with very low false alarm rates. Target ions from an ionized sample are identified and separated by the ion separator. The target ions are steered and deposited onto a SERS substrate for Raman spectroscopic analysis with an optical probe. The Raman spectrum is compared with reference spectra and the composition of the sample is identified. The ion current from the target ions can also be measured, preferably concurrently with the Raman spectrum measurement. Types of ion separators include a differential ion mobility spectrometer, an ion mobility spectrometer, or a mass spectrometer.

    Abstract translation: 使用表面增强拉曼光谱(SERS)和离子分离预过滤器(如离子光谱仪)检测和鉴定离子。 作为SERS的预过滤器的离子分离器的组合提供了具有非常低的误报率的高灵敏度检测器。 来自离子化样品的目标离子被离子分离器识别并分离。 目标离子被转向并沉积到SERS衬底上,用于使用光学探针进行拉曼光谱分析。 将拉曼光谱与参考光谱进行比较,并鉴定样品的组成。 也可以测量来自目标离子的离子电流,优选与拉曼光谱测量同时测量。 离子分离器的类型包括差示离子迁移谱仪,离子迁移谱仪或质谱仪。

Patent Agency Ranking