公开(公告)号：US3686262A

公开(公告)日：1972-08-22

申请号：US3686262D

申请日：1970-09-15

Applicant: STAMICARBON

Inventor： GROEN SIEMEN H ,  DEUMENS JOHANNES J M

IPC: C07C255/17 ,  C07C20060101 ,  C07C67/00 ,  C07C253/00 ,  C07C255/61 ,  C07C121/02 ,  C07C121/34

CPC classification number: C07C255/00

Abstract: A PROCESS FOR THE PREPARATION OF (2-CYANOETHYL) KETONES BY THE HYDROLYSIS OF THE CORRESPONDING (2-CYANOETHYL)-N-SUBSITUTED KETOIMINE WITH THE SUBSEQUENT RECOVERY OF A PRIMARY AMINE, THE PRIMARY AMINE BOILING AT A LOWER TEMPERATURE THAN WATER AND/OR FORMING WITH WATER AN AZEOTROPE BOILING AT A LOWER TEMPERATURE THAN WATER AND CARRYING ON ITS NITROGEN ATOM THE SAME GROUP AS THAT OF THE NITROGEN ATOM OF THE CORRESPONDING KETOIMINE IS DISCLOSED. WHEN THE RESULTING KETONE IS 5-CYANOPENTANONE-2 THIS MAY BE USED AS A STARTING PRODUCT FOR THE PREPARATION OF A-PIPECOLINE.

公开(公告)号：CA895909A

公开(公告)日：1972-03-21

申请号：CA895909D

Applicant: STAMICARBON

Inventor： GROEN SIEMEN H ,  DEUMENS JOHANNES J M

公开(公告)号：CA952529A

公开(公告)日：1974-08-06

申请号：CA107571

申请日：1971-03-12

Applicant: STAMICARBON

Inventor： GROEN SIEMEN H ,  DEUMENS JOHANNES J M ,  STIJFS PETRUS A M J

IPC: C07C209/48 ,  C07C209/52 ,  C07D295/02 ,  C07D295/027 ,  C07D295/033

Abstract: 1327335 Process for making piperidines STAMICARBON NV 19 April 1971 [12 March 1970] 23823/71 Heading C2C The invention comprises hydrogenating an N-substituted-4-cyanoaldimine, optionally in the presence of ammonia and a solvent, to afford piperidine or a C-substituted piperidine and a primary amine carrying the same substituent on the N-atom as is present on the N-atom of the aldimine. The examples describe the conversion of: N-cyclohexyl-4-cyano-2,2- dimethylbutyraldimine to 3,3-dimethylpiperidine, cyclohexylamine and 1,5-diamino-2,2-dimethylpentane; N - hexyl - 4 - cyano - 2,2 - dimethylbutyraldimine to 3,3-dimethylpiperidine, hexylamine and 1,5 - diamino - 2,2 - dimethylpentane; N - cyclohexyl - 4 - cyanobutyraldimine to piperidine, cyclohexylamine and 1,5-diaminopentane; N - cyclohexyl - 4 - cyano - 2 - ethyl - butyraldimine to 3 - ethyl - piperidine, cyclohexylamine and 2-ethyl-1,5-diaminopentane; N - hexyl - 2,2 - dimethyl - 4 - cyanobutyraldimine to 3,3 - dimethylpiperidine, 1 - hexyl - 3,3 - dimethylpiperidine and hexylamine; and N-cyclohexyl-4-cyano-2-propylbutyraldimine to 3-propylpiperidine, cyclohexylamine and 1-cyclohexyl-3-propylpiperidine

公开(公告)号：CA981268A

公开(公告)日：1976-01-06

申请号：CA109973

申请日：1971-04-08

Applicant: STAMICARBON

Inventor： LIPSCH JOHANNES M J G ,  JANSSEN PETRUS H J ,  DEUMENS JOHANNES J M ,  GROEN SIEMEN H

IPC: C07D215/06 ,  B01J23/00 ,  C07B61/00 ,  C07D211/12 ,  C07D211/62 ,  C07D211/70 ,  C07D213/08 ,  C07D213/09

公开(公告)号：CA917671A

公开(公告)日：1972-12-26

申请号：CA917671D

Applicant: STAMICARBON

Inventor： DEUMENS JOHANNES J M ,  GROEN SIEMEN H