公开(公告)号：EP0186117A2

公开(公告)日：1986-07-02

申请号：EP85116161.2

申请日：1985-12-18

Applicant: STAUFFER CHEMICAL COMPANY

Inventor： Heather, James Brian ,  Milano, Pamela Denise

IPC: C07C45/54 ,  C07C49/813 ,  C07C45/46 ,  C07C49/403 ,  C07C205/06 ,  C07C255/50 ,  C07C253/00 ,  C07C67/14 ,  C07C323/50

CPC classification number: C07C201/12 ,  C07C45/455 ,  C07C45/54 ,  C07C253/30 ,  C07C319/20 ,  C07C49/403 ,  C07C49/83 ,  C07C205/45 ,  C07C255/56 ,  C07C323/22

Abstract: An acylated diketonic compound is produced by rearrangement of the corresponding enol ester in the presence of a cyanide source. In one embodiment the cyanide source is employed with a molar excess of a moderate base, with respect to the enol ester. In another embodiment, the cyanide source is a stoichiometric amount, with respect to the enol ester, of potassium or lithium cyanide and a catalytic amount of a Crown ether is used.

Abstract translation: 通过在氰化物源的存在下重排相应的烯醇酯来制备酰化的二酮化合物。 在一个实施方案中，相对于烯醇酯，使用氰化物源与摩尔过量的中等碱。 在另一个实施方案中，氰化物源相对于烯醇酯为氰化钾或氰化锂的化学计量量，并且使用催化量的冠醚。

公开(公告)号：EP0186117A3

公开(公告)日：1987-06-16

申请号：EP85116161

申请日：1985-12-18

Applicant: STAUFFER CHEMICAL COMPANY

Inventor： Heather, James Brian ,  Milano, Pamela Denise

IPC: C07C45/54 ,  C07C49/813 ,  C07C45/46 ,  C07C49/403 ,  C07C79/36 ,  C07C121/76 ,  C07C120/00 ,  C07C67/14 ,  C07C149/32

CPC classification number: C07C201/12 ,  C07C45/455 ,  C07C45/54 ,  C07C253/30 ,  C07C319/20 ,  C07C49/403 ,  C07C49/83 ,  C07C205/45 ,  C07C255/56 ,  C07C323/22

Abstract: An acylated diketonic compound is produced by rearrangement of the corresponding enol ester in the presence of a cyanide source. In one embodiment the cyanide source is employed with a molar excess of a moderate base, with respect to the enol ester. In another embodiment, the cyanide source is a stoichiometric amount, with respect to the enol ester, of potassium or lithium cyanide and a catalytic amount of a Crown ether is used.

公开(公告)号：EP0219835A2

公开(公告)日：1987-04-29

申请号：EP86114442.6

申请日：1986-10-17

Applicant: STAUFFER CHEMICAL COMPANY

Inventor： Milano, Pamela Denise ,  James, Donald Richard

IPC: C07D401/12 ,  C07D239/38 ,  C07D239/34 ,  A01N43/54

CPC classification number: A01N53/00 ,  A01N43/54 ,  A01N47/20 ,  A01N47/30 ,  C07D239/34 ,  C07D239/38 ,  C07D401/12

Abstract: As new compounds, acyiaminoaryloxy and arylthio pyrimidines having the formula
wherein A is oxygen or sulfur; M is CH or N; X is hydrogen, lower alkyl, halo, methoxy, alkoxy, C,-C 3 alkylthio, cyano, carbomethoxy or trifluoromethyl; Z is


wherein R' is C 1 -C 8 straight, branched-chain or halo-alkyl, aryl; and R is hydrogen, C 1 -C 8 straight or branched chain alkyl, C 5 or C 6 cycloalkyl or ary

Abstract translation: 作为新化合物，具有式CHEM的酰氨基氧基和芳硫基嘧啶，其中A是氧或硫; M是CH或N; X是氢，低级烷基，卤素，甲氧基，烷氧基，C 1 -C 3烷硫基，氰基，甲酯基或三氟甲基; Z是其中R min是C 1 -C 8直链，支链或卤代烷基，芳基; R为氢，C1-C8直链或支链烷基，C5或C6环烷基或芳基

公开(公告)号：EP0186117B1

公开(公告)日：1990-11-22

申请号：EP85116161.2

申请日：1985-12-18

Applicant: STAUFFER CHEMICAL COMPANY

Inventor： Heather, James Brian ,  Milano, Pamela Denise

IPC: C07C45/54 ,  C07C49/813 ,  C07C45/46 ,  C07C49/403 ,  C07C205/06 ,  C07C255/50 ,  C07C253/00 ,  C07C67/14 ,  C07C323/50

CPC classification number: C07C201/12 ,  C07C45/455 ,  C07C45/54 ,  C07C253/30 ,  C07C319/20 ,  C07C49/403 ,  C07C49/83 ,  C07C205/45 ,  C07C255/56 ,  C07C323/22

公开(公告)号：EP0219835A3

公开(公告)日：1988-02-10

申请号：EP86114442

申请日：1986-10-17

Applicant: STAUFFER CHEMICAL COMPANY

Inventor： Milano, Pamela Denise ,  James, Donald Richard

IPC: C07D401/12 ,  C07D239/38 ,  C07D239/34 ,  A01N43/54

CPC classification number: A01N53/00 ,  A01N43/54 ,  A01N47/20 ,  A01N47/30 ,  C07D239/34 ,  C07D239/38 ,  C07D401/12

Abstract: As new compounds, acyiaminoaryloxy and arylthio pyrimidines having the formula
wherein A is oxygen or sulfur; M is CH or N; X is hydrogen, lower alkyl, halo, methoxy, alkoxy, C,-C 3 alkylthio, cyano, carbomethoxy or trifluoromethyl; Z is
wherein R' is C 1 -C 8 straight, branched-chain or halo-alkyl, aryl; and R is hydrogen, C 1 -C 8 straight or branched chain alkyl, C 5 or C 6 cycloalkyl or ary