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公开(公告)号：WO2020185746A1
公开(公告)日：2020-09-17
申请号：PCT/US2020/021838
申请日：2020-03-10
Applicant: STC. UNM
Inventor： PEREZ, Dominique, Renee , SKLAR, Larry, A. , CHIGAEV, Alexandre , FRANKS, Alison, F.
Abstract: The present invention is directed to previously identified inhibitors ofcAMP efflux (ICE) and their use in feaiing/niasking body odor, inhibiting, reducing and/or eliminating hyperhidrosis (excessive sweating), tanning skin or protecting skin before and/or after exposure to the sun as well as.for treating certain skin conditions, in one embodiment, the invention provides a method for inhibiting body odor, a condition that is characterized by an unpleasant odor from the products of the microbial sweat degradation. By inhibiting the efflux of the precursor compounds that are degraded, novel compounds are- capable of preventing unwanted odors. Deodorant compositions that employ this new approach for the control of bodily odor are provided, ICE compounds can also be used as. components, of cosmetic formulations including tanning and after-sun formulations, formulations for skin conditions as described herein and other cosmetic formulations.
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