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公开(公告)号：EP2486184A2
公开(公告)日：2012-08-15
申请号：EP10822839.6
申请日：2010-10-12
Applicant: STC.UNM
Inventor： WHITTEN, David , ISTA, Linnea , CORBITT, Thomas S. , OGAWA, Motokatsu , SCHANZE, Kirk , LOPEZ, Gabriel , NAGARAJAN, Ramanathan
IPC: D06M14/02 , D06M15/37 , D06M13/165 , D06M11/32 , D06M14/04
CPC classification number: A01N43/90 , D06M13/513 , D06M14/02 , D06M14/04 , D06M14/06 , D06M14/08 , D06M15/227 , D06M16/00 , D06M23/005 , D06M2400/01 , Y10T442/20 , Y10T442/2525 , A01N25/10 , A01N25/34
Abstract: The present disclosure describes the manufacture and use of soft surfaces such as fabrics bearing surface-grafted antimicrobial polymers.
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2.发明公开STRUCTURE, SYNTHESIS, AND APPLICATIONS FOR OLIGO PHENYLENE ETHYNYLENES 审中-公开结构，综合和OLIGOPHENYLENETHINYLENEN应用
公开(公告)号：EP2307350A2
公开(公告)日：2011-04-13
申请号：EP09771137.8
申请日：2009-06-26
Applicant: STC.UNM
Inventor： WHITTEN, David , TANG, Yanli , ZHOU, Zhijun , ISTA, Linnea , OGAWA, Motokatsu , KELLER, David , ANDREZEJEWSKI, Brett , LOPEZ, Gabriel , SCHANZE, Kirk
CPC classification number: C07C217/20 , A01N33/12 , A01N37/38
Abstract: Novel compounds generally referred to herein as cationic oligomeric phenylene ethynylenes (OPEs), methods of synthesizing OPEs and various uses for the OPEs are described. The compounds can be synthesized in both symmetrical (S-OPE) and non- symmetrical (N-OPE) forms. Suitable uses include sensor and biocidal applications. Reusable structures incorporating the OPEs that are able to capture and release biological species of interest are also described.
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3.发明申请
公开(公告)号：WO2009137129A3
公开(公告)日：2009-11-12
申请号：PCT/US2009/033943
申请日：2009-02-12
Applicant: STC.UNM , RUBIN, Robert , SITDIKOV, Ravil , ATANASSOV, Plamen , LOPEZ, Gabriel , KONSTANTINOV, Konstantin
Inventor： RUBIN, Robert , SITDIKOV, Ravil , ATANASSOV, Plamen , LOPEZ, Gabriel , KONSTANTINOV, Konstantin
IPC: G01N33/53 , G01N27/26 , G01N33/561
Abstract: A rapid electrochemical flow-through sensor and method for detecting the presence of autoantibodies in a fluid sample such as blood is shown and described. The sensor may take either a single- or multi-plexed form. The sensor comprises a fluid inlet, a reaction region comprising immobilized autoantigens and an electrode assembly, and a fluid outlet.
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Patent Agency Ranking
公开(公告)号：WO2009097174A3
公开(公告)日：2009-08-06
申请号：PCT/US2009/030304
申请日：2009-01-07
Applicant: STC.UNM , SITDIKOV, Ravil , IVNITSKIV, Dmitri , LOPEZ, Gabriel , RAMIREZ, Brianna , ATANASSOV, Plamen
Inventor： SITDIKOV, Ravil , IVNITSKIV, Dmitri , LOPEZ, Gabriel , RAMIREZ, Brianna , ATANASSOV, Plamen
IPC: G01N27/327 , G01N33/48 , G01N27/28 , G01N33/487 , G01N27/416
Abstract: A simple, fast, selective and highly sensitive electrochemical method assay and disposable device for detection of viruses, bacteria, proteins, DNA, and/or organic/inorganic compounds. The sensor has a multi-layered construction, with each successive layer performing a different function. The design further allows for the packing of numerous microscopic electrode transducers onto the small footprint of a biochip device, allowing for a high-density array of sensors.
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5.发明申请STABLE ELASTOMERIC NEGATIVE ACOUSTIC CONTRAST PARTICLES AND THEIR USE IN ACOUSTIC RADIATION FIELDS 审中-公开稳定的弹性体负反射粒子及其在声辐射场中的应用
公开(公告)号：WO2010132474A2
公开(公告)日：2010-11-18
申请号：PCT/US2010/034415
申请日：2010-05-11
Applicant: STC.UNM , LOPEZ, Gabriel , KADUCHAK, Gregory
Inventor： LOPEZ, Gabriel , KADUCHAK, Gregory
CPC classification number: C08L83/04 , A61K9/0009 , A61K9/1641 , A61K9/1682 , A61K47/34 , A61K49/225 , G01N33/538 , G01N33/54313
Abstract: We describe methods for synthesis and formulations of stable elastomeric negative acoustic contrast particles with controllable compressibility and density. These elastomeric negative acoustic contrast particles have a density/compressibility ratio that is less than that of water and therefore exhibit negative acoustic contrast under acoustic radiation exposure. This negative acoustic contrast allows our elastomeric negative acoustic contrast particles to be acoustically manipulated (e.g. separated) differently from other components (e.g. cells) within an aqueous solution. This disclosure also describes methods for biofunctionalization of the elastomeric negative acoustic contrast particles and as an example their use as platforms for bioassays. Potential applications of these elastomeric negative acoustic contrast particles include sensitive bioassays based on acoustic flow cytometry and other types of techniques that utilize acoustic fields, including ultrasound imaging and ultrasound triggered drug delivery.
Abstract translation: 我们描述了具有可压缩性和密度的稳定的弹性体负声学对比粒子的合成方法和配方。 这些弹性体负声学对比颗粒的密度/压缩比小于水的密度/压缩比，因此在声辐射暴露下呈现负的声学对比度。 这种负声学对比度允许我们的弹性体负声学对比粒子与水溶液中的其它组分（例如细胞）不同地被声学操纵（例如分离）。 本公开还描述了弹性体负声学对比粒子的生物功能化的方法，并且作为其用作生物测定平台的实例。 这些弹性体负声学对比粒子的潜在应用包括基于声流式细胞术的敏感生物测定和利用声场的其他类型的技术，包括超声成像和超声触发药物递送。
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公开(公告)号：WO2010132471A3
公开(公告)日：2010-11-18
申请号：PCT/US2010/034411
申请日：2010-05-11
Applicant: STC.UNM , LOPEZ, Gabriel , CARROLL, Nick , CUSHING, Kevin , PETSEV, Dimiter, N.
Inventor： LOPEZ, Gabriel , CARROLL, Nick , CUSHING, Kevin , PETSEV, Dimiter, N.
Abstract: We describe methods for synthesis and formulations of stable elastomeric negative acoustic contrast particles with controllable compressibility and density. These elastomeric negative acoustic contrast particles have a density/compressibility ratio that is less than that of water and therefore exhibit negative acoustic contrast under acoustic radiation exposure. This negative acoustic contrast allows our elastomeric negative acoustic contrast particles to be acoustically manipulated (e.g. separated) differently from other components (e.g. cells) within an aqueous solution. This disclosure also describes methods for biofunctionalization of the elastomeric negative acoustic contrast particles and as an example their use as platforms for bioassays. Potential applications of these elastomeric negative acoustic contrast particles include sensitive bioassays based on acoustic flow cytometry and other types of techniques that utilize acoustic fields, including ultrasound imaging and ultrasound triggered drug delivery.
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公开(公告)号：WO2009158606A9
公开(公告)日：2009-12-30
申请号：PCT/US2009/048838
申请日：2009-06-26
Applicant: STC.UNM , WHITTEN, David , TANG, Yanli , ZHOU, Zhijun , ISTA, Linnea , OGAWA, Motokatsu , KELLER, David , ANDREZEJEWSKI, Brett , LOPEZ, Gabriel , SCHANZE, Kirk
Inventor： WHITTEN, David , TANG, Yanli , ZHOU, Zhijun , ISTA, Linnea , OGAWA, Motokatsu , KELLER, David , ANDREZEJEWSKI, Brett , LOPEZ, Gabriel , SCHANZE, Kirk
Abstract: Novel compounds generally referred to herein as cationic oligomeric phenylene ethynylenes (OPEs), methods of synthesizing OPEs and various uses for the OPEs are described. The compounds can be synthesized in both symmetrical (S-OPE) and non- symmetrical (N-OPE) forms. Suitable uses include sensor and biocidal applications. Reusable structures incorporating the OPEs that are able to capture and release biological species of interest are also described.
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公开(公告)号：WO2008154412A3
公开(公告)日：2008-12-18
申请号：PCT/US2008/066168
申请日：2008-06-06
Applicant: STC.UNM , GUPTA, Gautam , LOPEZ, Gabriel , ATANASSOV, Plamen
Inventor： GUPTA, Gautam , LOPEZ, Gabriel , ATANASSOV, Plamen
Abstract: The disclosure provides a simple and effective way of synthesizing robust organic- inorganic hybrid gels and ultra-thin films using vaporization of a gel precursor. The gels are synthesized at relatively low temperature allowing the activity of the immobilized species to be maintained. The disclosure provides robust, synthetic, selective, active and/or passive transport systems in the form of functional biologically active species and mechanisms for forming them. These systems allow selective and passive or active transport of ionic, molecular and biological species through the incorporation of functional biological molecules and biomolecular assemblies in a rigid matrix.
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