公开(公告)号：US20160077107A1

公开(公告)日：2016-03-17

申请号：US14787928

申请日：2014-05-02

Applicant: STICHTING KATHOLIEKE UNIVERSITEIT

Inventor： Leonardus Antonius Bernardus Joosten ,  Mihai Gheorghe Netea ,  Johannes Willem Maarten van der Meer

IPC: G01N33/68 ,  C07K14/705 ,  C07K16/24 ,  A61K38/05 ,  G01N33/564

CPC classification number: G01N33/6869 ,  A61K38/00 ,  A61K38/05 ,  C07K14/70578 ,  C07K16/241 ,  C07K2317/31 ,  C07K2317/76 ,  C07K2319/30 ,  G01N33/564 ,  G01N33/6863 ,  G01N33/6866 ,  G01N33/6893 ,  G01N33/6896 ,  G01N2333/545 ,  G01N2800/065 ,  G01N2800/102 ,  G01N2800/107 ,  G01N2800/285 ,  G01N2800/52 ,  Y02A50/57

Abstract: The present invention relates to a method for assessing the efficacy of an inhibitor of a pro-inflammatory cytokine and/or of B cells in a subject and a method for treating said subject with said inhibitor provided the efficacy of said inhibitor has been determined as sufficient.

Abstract translation: 本发明涉及用于评估受试者中促炎细胞因子和/或B细胞抑制剂的功效的方法以及所述抑制剂治疗所述受试者的方法，只要所述抑制剂的功效已被确定为足够 。