公开(公告)号：US20200181564A1

公开(公告)日：2020-06-11

申请号：US16607824

申请日：2018-04-23

Applicant: STICHTING KATHOLIEKE UNIVERSITEIT

Inventor： Paul KOUWER ,  Alan ROWAN ,  Maarten JASPERS ,  Paula DE ALMEIDA

IPC: C12N5/00

Abstract: A double network hydrogel including a polymer (A) having a persistence length between 10 and 1000 nm; a flexible polymer (B), wherein the persistence length is measured according to single molecule force microscopy measurement, wherein polymer (B) has an extended coil conformation at a first condition and a collapsed globular conformation at a second condition. Polymer (A) preferably is a polyisocyanate, while polymer (B) is a crosslinked flexible polymer like for example PNIPAM. A method for making a double network hydrogel.