公开(公告)号：EP3781682A1

公开(公告)日：2021-02-24

申请号：EP19742978.0

申请日：2019-04-18

Applicant: Stichting VU

Inventor： GROSSMANN, Tom Norbert ,  PELAY GIMENO, Marta ,  HENNIG, Sven ,  NEUBACHER, Saskia Antonie

IPC: C12N9/96 ,  C12N9/52 ,  C12N9/64

公开(公告)号：WO2019203645A1

公开(公告)日：2019-10-24

申请号：PCT/NL2019/050229

申请日：2019-04-18

Applicant: STICHTING VU

Inventor： GROSSMANN, Tom Norbert ,  PELAY GIMENO, Marta ,  HENNIG, Sven ,  NEUBACHER, Saskia Antonie

IPC: C12N9/96 ,  C12N9/52 ,  C12N9/64

Abstract: The present invention relates to methods and cross-linkers for the macrocyclization of proteins. The invention is useful for increasing the stability of a protein.