中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

3 records (took 0.038 seconds)

    APPARATUS AND METHOD FOR NUCLEIC ACID SEQUENCING BASED ON NANOCHANNELS
    1.
    发明公开
    APPARATUS AND METHOD FOR NUCLEIC ACID SEQUENCING BASED ON NANOCHANNELS 审中-公开
    装置和方法用于核酸测序采用纳米渠道

    公开(公告)号：EP2927329A1

    公开(公告)日：2015-10-07

    申请号：EP15248047.1

    申请日：2015-04-03

    Applicant: STMicroelectronics Srl

    Inventor： Ferrara, Francesco ,  Bianchessi, Marco Angelo

    IPC: C12Q1/68 ,  G01N27/414 ,  G01N33/487

    CPC classification number: C12N15/101 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0627 ,  C12Q1/6869 ,  C12Q2523/307 ,  C12Q2563/157 ,  C12Q2565/607 ,  G01N27/44791 ,  G01N33/48721

    Abstract: An apparatus for nucleic acid sequencing includes a nanochannel (10) and a conveying device (5), configured to move a nucleic acid strand (F) through the nanochannel (10). The conveying device (5) includes: a first electrode (15), a second electrode (16), and a third electrode (17), which are arranged along the nanochannel (10) so as to be in contact with a fluid occupying the nanochannel (10), the second electrode (16) being arranged between the first electrode (15) and the third electrode (17); and a control unit (20) configured to apply a first voltage (V 1 ), a second voltage (V 2 ), and a third voltage (V 3 ), respectively, to the first electrode (15), the second electrode (16) and the third electrode (17), so as to control movement of the nucleic acid strand (F) through the nanochannel (10).

    Abstract translation: 用于核酸测序的设备包括纳米沟道（10）和输送装置（5），用于通过所述纳米沟道（10）移动的核酸海滩（F）。 输送装置（5）包括：第一电极（15），第二电极（16），以及沿所述纳米通道（10），其布置的第三电极（17），以便与流体占据接触 纳米通道（10），第二电极（16）的第一电极（15）和所述第三电极（17）之间被布置; 并且被配置为控制单元（20）施加第一电压（V 1），第二电压（V 2），以及第三电压（V 3），分别向第一电极（15），第二电极（16 ）和第三电极（17），以便通过纳米通道（10）来控制核酸海滩（F）的运动。

    APPARATUS AND METHOD FOR NUCLEIC ACID SEQUENCING BASED ON NANOWIRE DETECTORS
    2.
    发明公开
    APPARATUS AND METHOD FOR NUCLEIC ACID SEQUENCING BASED ON NANOWIRE DETECTORS 审中-公开
    VORRICHTUNG UND VERFAHRENFÜRNUCLEINSÄURE-SEQUENZIERUNG MIHILFE VON NANOFADENDETEKTOREN

    公开(公告)号：EP2927330A1

    公开(公告)日：2015-10-07

    申请号：EP15248048.9

    申请日：2015-04-03

    Applicant: STMicroelectronics Srl

    Inventor： Bianchessi, Marco Angelo ,  Ferrara, Francesco

    IPC: C12Q1/68 ,  G01N27/414 ,  G01N33/487

    CPC classification number: C12Q1/6874 ,  B82Y30/00 ,  G01N27/4146

    Abstract: An apparatus for nucleic acid sequencing includes: a base-detection device (4) in a detection site, the base-detection device (4) being configured to detect bases of a portion of a nucleic acid strand (F) at the detection site; and a conveying device (5), configured to extend the nucleic acid strand (F) and to cause the extended nucleic acid strand (F) to slide through the detection site along a path (A). The base-detection device (4) includes a plurality of field-effect nanowire detectors (21), arranged along the path (A) and each including a respective nanowire (25) and nucleic acid probes (27), which are defined by respective base sequences and are fixed to the respective nanowire (25).

    Abstract translation: 用于核酸测序的装置包括：检测位点中的碱基检测装置（4），所述碱基检测装置（4）被配置为检测所述检测部位的核酸链（F）的一部分的碱基; 以及输送装置（5），其被配置为延伸所述核酸链（F）并且使所述延伸的核酸链（F）沿着路径（A）穿过所述检测部位滑动。 基底检测装置（4）包括多个场效应纳米线检测器（21），沿着路径（A）布置，每个包括相应的纳米线（25）和核酸探针（27） 碱基序列并固定到相应的纳米线（25）。

Patent Agency Ranking