公开(公告)号：WO2017218789A1

公开(公告)日：2017-12-21

申请号：PCT/US2017/037700

申请日：2017-06-15

Applicant: STRECK, INC.

Inventor： TORRES, Maria ,  HANSON, Nancy ,  LECHNER, Joel ,  COSSETTE, Stephanie ,  SCHEER, Cathy ,  KREIFELS, Matthew ,  MORROW, Stacey ,  CONNELLY, Chris ,  PORTER, Laura, R. ,  FOWLER, Randy

IPC: C12Q1/68

Abstract: Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following:MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51 -like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.

Abstract translation: 用于检测对β-内酰胺抗生素的抗性的分析方法和方法，包括通过聚合酶链式反应或微阵列检测多种β-内酰胺酶家族特异性基因靶标。 一种或多种试剂盒，包括用于鉴定选自以下一种或多种的β-内酰胺酶基因的引物和/或探针：MOX样，FOX样，ACC样，ACT / MIR样，CMY样， 2样，DHA样，CTX-M-14样，CTX-M-15样，VIM样，NDM样，IMP样，KPC样和OXA-48样，OXA-51 如OXA-143样，OXA-58样，OXA-23样，OXA-24/40样，TEM样和SHV样。 试剂盒还可以包括用于鉴定赋予抗生素抗性的非-β内酰胺酶基因家族的一个或多个引物和/或探针，例如MCR-1基因。

公开(公告)号：EP3472350A1

公开(公告)日：2019-04-24

申请号：EP17735273.9

申请日：2017-06-15

Applicant: Streck, Inc.

Inventor： TORRES, Maria ,  HANSON, Nancy ,  LECHNER, Joel ,  COSSETTE, Stephanie ,  SCHEER, Cathy ,  KREIFELS, Matthew ,  MORROW, Stacey ,  CONNELLY, Chris ,  PORTER, Laura, R. ,  FOWLER, Randy

IPC: C12Q1/68