公开(公告)号：US20180127372A1

公开(公告)日：2018-05-10

申请号：US15574967

申请日：2016-05-18

Applicant: SUN PHARMA ADVANCED RESEARCH COMPANY LTD.

Inventor： Hemant Ashvinbhai CHOKSHI ,  Sabbirhusen Yusufbhai CHIMANWALA ,  Varun Anilkumar MEHTA ,  Prabal SENGUPTA ,  Chitturi Trinadha RAO

IPC: C07D213/75 ,  C07D401/12 ,  C07B43/06

CPC classification number: C07D213/75 ,  C07B43/06 ,  C07D401/12

Abstract: The present invention relates to novel amidoheteroaryl aroyl hydrazide ethynes as tyrosine kinase inhibitors, process of preparation thereof, and use of the compounds for preparation of pharmaceutical compositions in the therapeutic treatment of disorders related to tyrosine kinases in humans.