公开(公告)号：WO1994023650A1

公开(公告)日：1994-10-27

申请号：PCT/US1994004055

申请日：1994-04-19

Applicant: SURVIVAL TECHNOLOGY, INC. ,  THE JOHNS-HOPKINS UNIVERSITY

Inventor： SURVIVAL TECHNOLOGY, INC. ,  THE JOHNS-HOPKINS UNIVERSITY ,  REINHOLD, Herbert, E., Jr. ,  VALENTINE, Martin, D. ,  MONROE, O., Napoleon

IPC: A61B05/08

CPC classification number: A61B5/411 ,  A61B5/0871

Abstract: The present invention provides a peak flow meter which facilitates a subject's compliance with the use thereof. In one embodiment, the peak flow meter provides an alarm (58) for indicating that the subject is due for a peak expiratory flow rate evaluation when the subject has failed to use the peak flow meter after a predetermined period of time. In another embodiment, the peak flow meter is provided with circuitry (40) which derives a data result corresponding to the peak expiratory flow rate of air blown into the peak flow meter for a number of blows. A first comparator (50) determines the best data result within the number of blows and a memory (48) stores each best data result. A second comparator (54) compares each best data result to a specified value and provides an enabling signal to an alarm (58) when a best data result is a predetermined amount lower than the specified value.

Abstract translation: 本发明提供了一种峰值流量计，其有助于受试者遵守其使用。 在一个实施例中，当在预定时间段之后对象未能使用峰值流量计时，峰值流量计提供用于指示受试者为达到峰值呼气流量评估而引起的报警（58）。 在另一个实施例中，峰值流量计设置有电路（40），该电路（40）导出对应于吹入峰值流量计的空气的峰值呼气流量对应于多次打击的数据结果。 第一比较器（50）确定在打击次数内的最佳数据结果，并且存储器（48）存储每个最佳数据结果。 第二比较器（54）将最佳数据结果与指定值进行比较，并且当最佳数据结果是比指定值低的预定量时，向报警器（58）提供使能信号。

公开(公告)号：WO1991016094A1

公开(公告)日：1991-10-31

申请号：PCT/US1991002289

申请日：1991-04-10

Applicant: SURVIVAL TECHNOLOGY INC.

Inventor： SURVIVAL TECHNOLOGY INC. ,  MONROE, O., Napoleon ,  DALLING, N., Lawrence ,  MESA, Clarence, M.

IPC: A61M05/20

CPC classification number: A61M5/2066 ,  A61M2005/1787 ,  A61M2005/206

Abstract: The medicament container assembly comprises a container (60) having a forward end (62) a hypodermic needle (92) having a sharpened end (90), and first and second liquid medicaments (102, 108). A pair of pistons (70, 80), and a closure assembly (66) are provided for sealingly confining the first liquid medicament (102) and the needle (92) in mutually communicating relation in a forward storage position within the container (60); sealingly confining the second liquid medicament (108) within the container (60) in a separate rearward storage position; and enabling the power stroke to cause a progressive movement of the first medicament (102) outwardly of the sharpened end of the needle as the sharpened end (90) of the needle (92) moves from the position of entry into the skin into the full depth position, and a progressive movement of the second medicament (108) outwardly of the sharpened end (90) of the needle (92) generally after the sharpened end of the needle has reached the full depth position.

Abstract translation: 药物容器组件包括容器（60），其具有前端（62）具有尖端（90）的皮下注射针（92）和第一和第二液体药物（102,108）。 提供一对活塞（70,80）和闭合组件（66），用于将第一液体药物（102）和针（92）在容器（60）内的向前储存位置中相互连通的关系密封地限制， ; 将第二液体药物（108）密封地限制在容器（60）内的单独的向后存储位置; 并且当所述针（92）的所述锋利末端（90）从进入所述皮肤的位置移动到所述皮肤的位置时，使得所述动力行程使得所述第一药剂（102）向所述针尖的尖端向外移动， 深度位置和第二药剂（108）在针的尖端（95）的外侧逐渐移动到针的尖端（90）之后，通常在针的尖端已经达到全深度位置之后。

公开(公告)号：WO1995015777A1

公开(公告)日：1995-06-15

申请号：PCT/US1994013196

申请日：1994-11-22

Applicant: SURVIVAL TECHNOLOGY, INC.

Inventor： SURVIVAL TECHNOLOGY, INC. ,  MESA, C., Michael ,  DALLING, M., Lawrence ,  LOWERY, Sandra, A. ,  MONROE, O., Napoleon

IPC: A61M05/315

CPC classification number: A61M5/2033 ,  A61M5/24 ,  A61M5/286 ,  A61M5/3129 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/3131

Abstract: An injection device (10) comprises a plastic or metal container (26) adapted to contain a charge of medicament. The container has at least an inner surface coated with polyparaxylylene (29). A needle (40) is cooperative with the container so as to be communicable with the medicament and provides a passage through which the medicament can be forced into the flesh of an individual. A plunger (36) is disposed in the container in slidably sealed relation with the polyparaxylylene coating provided on the inner surface of the container. The plunger is movable through the container toward a generally forward end thereof to force the medicament through the needle and into the flesh of the individual.

Abstract translation: 注射装置（10）包括适于容纳药剂的塑料或金属容器（26）。 容器至少具有涂覆有聚对二甲苯（29）的内表面。 针（40）与容器协作以便与药物连通，并提供一种通道，药物可以通过该通道被迫进入个体的肉体。 柱塞（36）与容器内表面上设置的聚对二甲苯涂层呈滑动密封的关系设置在容器中。 柱塞可以通过容器朝向其大致前端移动，以迫使药物穿过针头并进入个体的肉体。

公开(公告)号：EP0525048A1

公开(公告)日：1993-02-03

申请号：EP91908108.0

申请日：1991-04-10

Applicant: SURVIVAL TECHNOLOGY, INC.

Inventor： MONROE, O., Napoleon ,  DALLING, N., Lawrence ,  MESA, Clarence, M.

IPC: A61M5

CPC classification number: A61M5/2066 ,  A61M2005/1787 ,  A61M2005/206

Abstract: Un ensemble de réservoir pour médicament comprend un réservoir (60) ayant une extrémité avant (62), une aiguille hypodermique (92) pourvue d'une extrémité pointue (90), ainsi qu'un premier et un deuxième médicaments liquides (102, 108). Une paire de pistons (70, 80) et un système de fermeture (66) sont prévus pour enfermer hermétiquement le premier médicament liquide (102) et l'aiguille (92) de manière à ce qu'ils soient en communication réciproque dans une position de stockage à l'avant, à l'intérieur du réservoir (60), les pistons (70, 80) et le système de fermeture (66) servent également à enfermer hermétiquement le deuxième médicament liquide (08) dans le réservoir (60) dans une position séparée de stockage à l'arrière, et ils permettent à la course de détente de provoquer la sortie progressive du premier médicament (102) à l'extérieur de l'extrémité pointue de l'aiguille lorsque ladite extrémité (90) pointue de l'aiguille (92) passe de la position de piqûre superficielle, lors de son introduction dans la peau, à la position de profondeur totale, ladite course de détente entraînant progressivement le deuxième médicament (108) hors de l'extrémité pointue de l'aiguille (92) peu de temps après que l'extrémité pointue de l'aiguille ait atteint la position de profondeur totale.

公开(公告)号：EP0732950A1

公开(公告)日：1996-09-25

申请号：EP95904071.0

申请日：1994-11-22

Applicant: SURVIVAL TECHNOLOGY, INC.

Inventor： MESA, C., Michael ,  DALLING, M., Lawrence ,  LOWERY, Sandra, A. ,  MONROE, O., Napoleon

IPC: A61M5

CPC classification number: A61M5/2033 ,  A61M5/24 ,  A61M5/286 ,  A61M5/3129 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/3131

Abstract: An injection device (10) comprises a plastic or metal container (26) adapted to contain a charge of medicament. The container has at least an inner surface coated with polyparaxylylene (29). A needle (40) is cooperative with the container so as to be communicable with the medicament and provides a passage through which the medicament can be forced into the flesh of an individual. A plunger (36) is disposed in the container in slidably sealed relation with the polyparaxylylene coating provided on the inner surface of the container. The plunger is movable through the container toward a generally forward end thereof to force the medicament through the needle and into the flesh of the individual.

公开(公告)号：EP0525048B1

公开(公告)日：1997-06-25

申请号：EP91908108.3

申请日：1991-04-10

Applicant: SURVIVAL TECHNOLOGY, INC.

Inventor： MONROE, O., Napoleon ,  DALLING, N., Lawrence ,  MESA, Clarence, M.

IPC: A61M5/20

CPC classification number: A61M5/2066 ,  A61M2005/1787 ,  A61M2005/206

Abstract: The medicament container assembly comprises a container (60) having a forward end (62) a hypodermic needle (92) having a sharpened end (90), and first and second liquid medicaments (102, 108). A pair of pistons (70, 80), and a closure assembly (66) are provided for sealingly confining the first liquid medicament (102) and the needle (92) in mutually communicating relation in a forward storage position within the container (60); sealingly confining the second liquid medicament (108) within the container (60) in a separate rearward storage position; and enabling the power stroke to cause a progressive movement of the first medicament (102) outwardly of the sharpened end of the needle as the sharpened end (90) of the needle (92) moves from the position of entry into the skin into the full depth position, and a progressive movement of the second medicament (108) outwardly of the sharpened end (90) of the needle (92) generally after the sharpened end of the needle has reached the full depth position.