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1.发明授权公开(公告)号：US12076724B2
公开(公告)日：2024-09-03
申请号：US16998040
申请日：2020-08-20
Applicant: SYSMEX CORPORATION
Inventor： Kazuhiro Yamada , Kazuki Asao , Keisuke Kuwano
CPC classification number: B01L3/5085 , B01L9/06 , G01N21/01 , G01N21/6428 , G01N21/85 , G01N33/4915 , B01L2200/025 , B01L2200/143 , B01L2300/0627 , G01N2021/6439 , G01N2201/06113 , G01N2201/0633 , G01N2201/0636
Abstract: A specimen processing apparatus performs processing on a specimen contained in a container. The specimen processing apparatus includes: holders having different shapes, each of the holders being configured to hold the container; a holder placement unit that comprises holder receiving portions having different shapes, the shapes of the holder receiving portions corresponding to the shapes of the holders; and a specimen processing unit that performs processing on the specimen contained in the container held by one of the holders placed on the holder placement unit.
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2.发明授权公开(公告)号：US11946866B2
公开(公告)日：2024-04-02
申请号：US17345645
申请日：2021-06-11
Applicant: SYSMEX CORPORATION
Inventor： Kazuhiro Yamada , Shohei Matsumoto , Yusuke Konishi
CPC classification number: G01N21/6428 , C12Q1/6841 , G01N21/6456 , G01N21/6458 , G06T7/0014 , G01N2021/6439 , G01N2021/6441 , G02B21/16 , G02B21/365 , G02B27/1006 , G02B27/141 , G06T2207/10056 , G06T2207/30024
Abstract: Disclosed is a fluorescence image analyzing apparatus including a light source that emits light to a sample including a plurality of cells labeled with a fluorescent dye at a target site, an imaging unit that captures a fluorescence image of each of the cells that emit fluorescence by being irradiated with the light, a fluorescence image of the cell, and a processing unit that processes the fluorescence image captured by the imaging unit to acquire a bright spot pattern of fluorescence in the fluorescence image. The processing unit selects a reference pattern corresponding to a measurement item of the sample from a plurality of reference patterns corresponding to a plurality of measurement items and generates information used for determination of the sample based on the bright spot pattern of fluorescence in the fluorescence image and the selected reference pattern.
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公开(公告)号：US10852238B2
公开(公告)日：2020-12-01
申请号：US16514789
申请日：2019-07-17
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada
Abstract: A fluorescence image analyzer, analyzing method, and pretreatment evaluation method capable of determining with high accuracy whether a sample is positive or negative are provided. A pretreatment part performs pretreatment including a step of labeling a target site with a fluorescent dye to prepare a sample. A fluorescence image analyzer measures and analyzes the sample. The fluorescent image analyzer includes light sources to irradiate light on the sample, imaging part to capture the fluorescent light given off from the sample irradiated by light, and processing part for processing the fluorescence image captured by the imaging part. The processing part extracts the bright spot of fluorescence generated from the fluorescent dye that labels the target site from the fluorescence image for each of a plurality of cells included in the sample, and generates information used for determining whether the sample is positive or negative based on the bright spots extracted for each of the plurality of cells.
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公开(公告)号：US09500581B2
公开(公告)日：2016-11-22
申请号：US14866246
申请日：2015-09-25
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada , Kazuhiro Sasaki
CPC classification number: G01N21/53 , G01N15/1459 , G01N33/4915 , G01N2015/0073 , G01N2015/1006 , G01N2015/1477 , G01N2800/22
Abstract: A blood analyzer comprises a flow cell, a first light source, a second light source, a first light receiving part, a second light receiving part, and a processing unit. The processing unit is configured to make determinations related to the types of microcytic anemia based on a first scattered light information based on the signals output from the first light receiving part, and a second scattered light information based on the signals output from the second light receiving part.
Abstract translation: 血液分析仪包括流通池，第一光源，第二光源，第一光接收部，第二光接收部和处理单元。 处理单元被配置为基于基于从第一光接收部输出的信号的第一散射光信息和基于从第二光接收输出的信号的第二散射光信息来进行与微血液性贫血的类型相关的测定 部分。
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公开(公告)号：US10094760B2
公开(公告)日：2018-10-09
申请号：US15341687
申请日：2016-11-02
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada , Takeshi Yamamoto
Abstract: A particle measuring apparatus includes a flow cell configured to flow a specimen, a first light source configured to emit light having a first wavelength, and a second light source configured to emit light having a second wavelength different from the first wavelength. An irradiation optical system is configured to irradiate the flow cell with light emitted from the first light source and the second light source. The irradiation optical system includes a dichroic mirror configured to transmit the light emitted from the first light source and reflect the light emitted from the second light source, and a light collecting lens configured to collect the light emitted from the first and second light sources and passed through the dichroic mirror at the flow cell. The second light source and the dichroic mirror are turnable about rotation axis that are orthogonal to one another.
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Patent Agency Ranking
公开(公告)号：US09513206B2
公开(公告)日：2016-12-06
申请号：US14227618
申请日：2014-03-27
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada , Takeshi Yamamoto
CPC classification number: G01N15/1436 , G01N15/1459 , G01N15/1463 , G01N21/53 , G01N35/026 , G01N2015/0065 , G01N2015/1006 , G01N2035/00356 , G01N2035/0415 , G01N2201/068
Abstract: A particle measuring apparatus comprising a flow cell configured to flow a specimen, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, an irradiation optical system configured to irradiate the flow cell with light emitted from the first light source and the second light source, a first light receiving portion configured to receive scattered light obtained by irradiating a measurement particle passing through the flow cell with light from the first light source, and a second light receiving portion configured to receive scattered light obtained by irradiating a measurement particle passing through the flow cell with light from the second light source.
Abstract translation: 一种粒子测量装置，包括被配置为流动样本的流动池，被配置为发射具有第一波长的光的第一光源，被配置为发射具有不同于第一波长的第二波长的光的第二光源，被配置为 利用从第一光源和第二光源发射的光照射流动池，第一光接收部分，被配置为接收通过用来自第一光源的光照射通过流动池的测量颗粒获得的散射光，以及 第二光接收部分，被配置为接收通过用来自第二光源的光照射通过流动池的测量颗粒获得的散射光。
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公开(公告)号：US11340170B2
公开(公告)日：2022-05-24
申请号：US17061255
申请日：2020-10-01
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada
Abstract: A fluorescence image analyzer, analyzing method, and pretreatment evaluation method capable of determining with high accuracy whether a sample is positive or negative are provided. A pretreatment part performs pretreatment including a step of labeling a target site with a fluorescent dye to prepare a sample. A fluorescence image analyzer measures and analyzes the sample. The fluorescent image analyzer includes light sources to irradiate light on the sample, imaging part to capture the fluorescent light given off from the sample irradiated by light, and processing part for processing the fluorescence image captured by the imaging part. The processing part extracts the bright spot of fluorescence generated from the fluorescent dye that labels the target site from the fluorescence image for each of a plurality of cells included in the sample, and generates information used for determining whether the sample is positive or negative based on the bright spots extracted for each of the plurality of cells.
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公开(公告)号：US09778178B2
公开(公告)日：2017-10-03
申请号：US14227650
申请日：2014-03-27
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada , Yasuyuki Kawashima , Seiichiro Tabata
CPC classification number: G01N21/49 , G01N15/1434 , G01N15/1459 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1402
Abstract: A blood cell analyzer comprises a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light obtained by irradiating the blood cells passing through the flow cell with light from the first light source, a second light receiving portion configured to receive second scattered light obtained by irradiating the blood cells passing through the flow cell with light from the second light source, and a control section configured to discriminate at least red blood cells from the blood cells contained in the measurement specimen based on detection signals output from the first light receiving portion and the second light receiving portion, respectively.
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9.发明授权公开(公告)号：US11085880B2
公开(公告)日：2021-08-10
申请号：US15951562
申请日：2018-04-12
Applicant: SYSMEX CORPORATION
Inventor： Kazuhiro Yamada , Shohei Matsumoto , Yusuke Konishi
Abstract: Disclosed is a fluorescence image analyzing apparatus including a light source that emits light to a sample including a plurality of cells labeled with a fluorescent dye at a target site, an imaging unit that captures a fluorescence image of each of the cells that emit fluorescence by being irradiated with the light, a fluorescence image of the cell, and a processing unit that processes the fluorescence image captured by the imaging unit to acquire a bright spot pattern of fluorescence in the fluorescence image. The processing unit selects a reference pattern corresponding to a measurement item of the sample from a plurality of reference patterns corresponding to a plurality of measurement items and generates information used for determination of the sample based on the bright spot pattern of fluorescence in the fluorescence image and the selected reference pattern.
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公开(公告)号：US10401289B2
公开(公告)日：2019-09-03
申请号：US15608380
申请日：2017-05-30
Applicant: Sysmex Corporation
Inventor： Kazuhiro Yamada
Abstract: A fluorescence image analyzer, analyzing method, and pretreatment evaluation method capable of determining with high accuracy whether a sample is positive or negative are provided. A pretreatment part 20 performs pretreatment including a step of labeling a target site with a fluorescent dye to prepare a sample 20a. A fluorescence image analyzer 10 measures and analyzes the sample 20a. The fluorescent image analyzer 10 includes light sources 121 to 124 to irradiate light on the sample 20a, imaging part 154 to capture the fluorescent light given off from the sample 20a irradiated by light, and processing part 11 for processing the fluorescence image captured by the imaging part 154. The processing part 11 extracts the bright spot of fluorescence generated from the fluorescent dye that labels the target site from the fluorescence image for each of a plurality of cells included in the sample 20a, and generates information used for determining whether the sample 20a is positive or negative based on the bright spots extracted for each of the plurality of cells.
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