公开(公告)号：US20190049383A1

公开(公告)日：2019-02-14

申请号：US16055201

申请日：2018-08-06

Applicant: SYSMEX CORPORATION

Inventor： Osamu KIKUCHI ,  Takahito MIHARA ,  Yuji MASUDA ,  Atsushi SHIRAKAMI ,  Takuma WATANABE ,  Daigo FUKUMA ,  Masaharu SHIBATA

IPC: G01N21/64

Abstract: A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

公开(公告)号：US20180024148A1

公开(公告)日：2018-01-25

申请号：US15657962

申请日：2017-07-24

Applicant: Sysmex Corporation

Inventor： Yuhgi SUZUKI ,  Takuma WATANABE

IPC: G01N33/80 ,  G01N1/30 ,  G01N21/64

CPC classification number: G01N33/80 ,  C12Q1/06 ,  G01N1/30 ,  G01N15/1429 ,  G01N15/1456 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/56905 ,  G01N2015/0073 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1497 ,  G01N2021/6439 ,  G01N2333/445 ,  Y02A50/58

Abstract: Disclosed is a blood analyzer that includes: a sample preparation unit configured to mix a blood specimen and a fluorescent dye for staining nucleic acid to prepare a measurement sample; a light receiver configured to receive fluorescence and scattered light that are generated by light being applied to the measurement sample prepared by the sample preparation unit; and a controller programmed to determine whether or not infection with Plasmodium has occurred, on the basis of a value representing variation of a distribution of first particles in a range where single-ring form of red blood cells appear, the range where single-ring form of red blood cells appear being identified according to fluorescence intensities and scattered light intensities obtained by processing of signals from the light receiver.

公开(公告)号：US20230089109A1

公开(公告)日：2023-03-23

申请号：US18060527

申请日：2022-11-30

Applicant: SYSMEX CORPORATION

Inventor： Osamu KIKUCHI ,  Takahito MIHARA ,  Yuji MASUDA ,  Atsushi SHIRAKAMI ,  Takuma WATANABE ,  Daigo FUKUMA ,  Masaharu SHIBATA

IPC: G01N21/64 ,  G01N33/80 ,  G01N15/10 ,  G01N15/14 ,  G01N35/00 ,  G01N33/96

Abstract: A blood analyzer according to one or more embodiments may include: a specimen preparation part that prepares a measurement specimen by mixing a reagent into a blood preparation; a measurement part that measures the measurement specimen; a measurement mode selection unit that receives an input of a type of blood preparation as a measurement target selected from a plurality of types of blood preparations; and a controller. The controller may cause the specimen preparation part to prepare the measurement specimen depending on the selected type of blood preparation.

公开(公告)号：US20200025778A1

公开(公告)日：2020-01-23

申请号：US16585982

申请日：2019-09-27

Applicant: Sysmex Corporation

Inventor： Yuhgi SUZUKI ,  Takuma WATANABE

IPC: G01N33/80 ,  C12Q1/06 ,  G01N15/14 ,  G01N33/569 ,  G01N1/30 ,  G01N21/64

Abstract: Disclosed is a blood analyzer that includes: a sample preparation unit configured to mix a blood specimen and a fluorescent dye for staining nucleic acid to prepare a measurement sample; a light receiver configured to receive fluorescence and scattered light that are generated by light being applied to the measurement sample prepared by the sample preparation unit; and a controller programmed to determine whether or not infection with Plasmodium has occurred, on the basis of a value representing variation of a distribution of first particles in a range where single-ring form of red blood cells appear, the range where single-ring form of red blood cells appear being identified according to fluorescence intensities and scattered light intensities obtained by processing of signals from the light receiver.

公开(公告)号：US20160041097A1

公开(公告)日：2016-02-11

申请号：US14819027

申请日：2015-08-05

Applicant: Sysmex Corporation

Inventor： Munehisa IZUKA ,  Takuma WATANABE

IPC: G01N21/64 ,  G01N21/49 ,  G01N15/14 ,  G01N33/49

CPC classification number: G01N21/6428 ,  G01N15/1434 ,  G01N21/49 ,  G01N33/49 ,  G01N33/56905 ,  G01N2015/0073 ,  G01N2015/1486 ,  G01N2021/6439 ,  G01N2201/06113 ,  Y02A50/58

Abstract: A blood analyzing method comprises irradiating light on a measurement sample prepared using fluorescent dye so as to produce a difference in fluorescence intensity between reticulocytes and mature red blood cells in a blood sample, detecting scattered light and fluorescent light given off from blood cells in the measurement sample, and obtaining fluorescence data related to the fluorescent light and scattered light data related to the scattered light for each blood cell, determining the possibility of the presence of plasmodium falciparum parasites in the blood sample based on the distribution conditions of blood cells in the reticulocyte distribution range based on the scattered light data and the fluorescent light data.

Abstract translation: 血液分析方法包括将光照射在使用荧光染料制备的测量样品上，以在血液样品中产生网织红细胞和成熟红细胞之间的荧光强度差异，检测在测量中从血细胞释放的散射光和荧光 样品，并获得与荧光相关的荧光数据和与每个血细胞的散射光相关的散射光数据，根据网织红细胞中血细胞的分布情况确定血液样品中存在恶性疟原虫寄生虫的可能性 基于散射光数据和荧光数据的分布范围。