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公开(公告)号：US4004150A
公开(公告)日：1977-01-18
申请号：US573766
申请日：1975-05-01
Applicant: Samuel Natelson
Inventor： Samuel Natelson
CPC classification number: G01N21/253 , G01N35/028 , G01N2201/0813
Abstract: The present invention contemplates an arrangement for analyzing a plurality of components in a single specimen which comprises placing a diluted specimen into a storage cup which is part of a sample carrier system, containing storage and reaction cups, transferring aliquots of the diluted solutions of the sample from the storage to the reaction cups, presenting the rows of the reaction cups to a work station, sequentially, adding a reagent to each of the reaction cups and moving the reaction cups into a work field where beams of light passing through the various reaction cups can be scanned and the components contained in the reaction cups can be assayed by means of a single detector attached to a computer and print-out system.
Abstract translation: 本发明考虑了一种用于分析单个样品中的多个组分的装置，其包括将稀释的样品放置在作为样品载体系统的一部分的储存杯中，所述储存杯包含储存和反应杯，转移样品的稀释溶液的等分试样 从储存器到反应杯，依次将反应杯排排列到工作站，向每个反应杯中加入试剂，并将反应杯移动到工作场中，其中通过各种反应杯的光束 可以扫描并且包含在反应杯中的组分可以通过连接到计算机和打印输出系统的单个检测器进行测定。
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公开(公告)号：US4264560A
公开(公告)日：1981-04-28
申请号：US106550
申请日：1979-12-26
Applicant: Samuel Natelson
Inventor： Samuel Natelson
CPC classification number: G01N35/00009 , G01N35/1079
Abstract: An arrangement for chemical analysis of a small quantity of sample wherein a specimen of a small size is passed through a porous distribution first medium onto a reagent-containing second medium is disclosed. The reagent-containing second medium is a thin, flat, liquid-impervious medium. A reagent is encapsulated upon the second medium as a flat, liquid-phase surface. The first and second mediums are so arranged and disposed that when firmly pressed together, the encapsulated liquid reagent will be liberated and the specimen will be distributed through the first medium onto the liquid-phase liberated reagent where the subsequent reaction of the liquid-phase reagent and the specimen can then be identified by reading means.
Abstract translation: 公开了一种用于小量样品的化学分析的装置，其中小尺寸的样品通过多孔分布第一介质到含有试剂的第二介质上。 含有试剂的第二介质是薄的，扁平的不透液体的介质。 试剂作为平坦的液相表面封装在第二介质上。 第一和第二介质被布置和布置成使得当牢固地压在一起时，封装的液体试剂将被释放，并且样品将通过第一介质分布到液相释放试剂上，随后液相试剂 然后可以通过阅读手段识别样本。
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公开(公告)号：US3951605A
公开(公告)日：1976-04-20
申请号：US495671
申请日：1974-08-08
Applicant: Samuel Natelson
Inventor： Samuel Natelson
CPC classification number: G01N35/026 , G01N2035/0437 , Y10S436/808 , Y10S436/81
Abstract: An instrument for quantitative analysis to measure a minute quantity of antigens or antibodies in a sample. There is a defined travel path for holding sample container holding means thereon, moving means coupled to said travel path to move a plurality of containers in a gang along said travel path, a work station including sensing means to sense a passing container in the container gang to align the containers at said work station. Probes at the work station are disposed above the containers when aligned at the work station. Lift means are provided for lowering and raising the probes into and out of the containers so as to add and remove liquid therefrom and program means control the operation of the instrument including the repetitive addition and removal of fluid from the containers whereby reagents are added to said containers, to lay down a film of immunologically active substance on walls of the containers. Liquid is then removed from the containers and the containers are washed repetitiously by successive additions and removals of a wash solution so as to leave the tubes coated with the immunologically active substance free of contaminating impurities.
Abstract translation: 用于定量分析以测量样品中微量抗原或抗体的仪器。 存在用于保持样本容器保持装置的限定的行进路径，联接到所述行进路径的移动装置沿着所述行进路径移动组中的多个容器，工作站包括感测装置，用于感测容器组中的经过的容器 以在所述工作站处对齐容器。 在工作站对齐时，工作站的探测器放置在容器上方。 设置提升装置用于将探针放入和移出容器，以便从其中添加和移出液体，并且程序装置控制仪器的操作，包括从容器重复添加和除去流体，由此将试剂加入到所述容器中 容器，在容器的壁上铺设免疫活性物质的薄膜。 然后从容器中取出液体，并通过连续添加和清除洗涤溶液重复洗涤容器，以便使涂覆有免疫活性物质的管没有污染杂质。
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