公开(公告)号：US20020114820A1

公开(公告)日：2002-08-22

申请号：US10058125

申请日：2002-01-29

Applicant: SemBioSys Genetics Inc.

Inventor： Harm M. Deckers ,  Gijs Van Rooijen ,  Joseph Boothe ,  Janis Goll ,  Maurice M. Moloney

IPC: A61K006/00 ,  A61K007/00

CPC classification number: C11B1/10 ,  A23D7/001 ,  A23D7/003 ,  A23G3/343 ,  A23G3/346 ,  A23G3/40 ,  A23G3/48 ,  A23G4/066 ,  A23G4/068 ,  A23G9/327 ,  A23G9/42 ,  A23G2200/08 ,  A23G2200/14 ,  A23K20/168 ,  A23K50/80 ,  A23L9/10 ,  A23L23/00 ,  A23L27/18 ,  A23L27/60 ,  A23P20/10 ,  A61K8/06 ,  A61K8/66 ,  A61K8/922 ,  A61K9/0014 ,  A61K36/00 ,  A61K36/31 ,  A61K47/44 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/08 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  C09D5/022 ,  Y02A40/818 ,  Y10S514/828 ,  Y10S514/845 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/848 ,  Y10S514/865 ,  Y10S514/882 ,  Y10S514/887 ,  Y10S514/937 ,  A61K2300/00

Abstract: The present invention provides novel emulsion formulations which comprise oil bodies. The invention also provides a method for preparing the emulsions and the use of the emulsions in products for topical application to the skin. The products are very mild to the skin and may be easily formulated into a wide variety of personal care and dermatological products.

Abstract translation: 本发明提供了包含油体的新型乳液制剂。 本发明还提供了一种制备乳液的方法以及在产品中使用乳剂以局部施用于皮肤。 产品对皮肤非常温和，可以很容易地配制成各种个人护理和皮肤病学产品。

公开(公告)号：US20030166162A1

公开(公告)日：2003-09-04

申请号：US10322746

申请日：2002-12-19

Applicant: SemBioSys Genetics Inc.

Inventor： Gijs Van Rooijen ,  Joenel Alcantara ,  Maurice M. Moloney

IPC: C12P021/04 ,  C12N009/00

CPC classification number: C07K14/61 ,  A23L33/17 ,  C07K14/815 ,  C07K2319/00 ,  C07K2319/02 ,  C07K2319/21 ,  C07K2319/50 ,  C07K2319/75 ,  C12N9/50 ,  C12N15/62

Abstract: An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polypeptide released under the appropriate conditions.

公开(公告)号：US20030177537A1

公开(公告)日：2003-09-18

申请号：US10324131

申请日：2002-12-20

Applicant: SemBioSys Genetics Inc.

Inventor： Maurice M. Moloney ,  Gijs Van Rooijen

IPC: A01H001/00 ,  C12N015/82

CPC classification number: C12N9/6483 ,  C07K14/415 ,  C07K14/545 ,  C07K14/61 ,  C07K14/8139 ,  C07K14/815 ,  C07K2319/00 ,  C07K2319/02 ,  C12N9/6429 ,  C12N15/8222 ,  C12N15/8234 ,  C12N15/8241 ,  C12N15/8242 ,  C12N15/8257 ,  C12Y304/21005 ,  C12Y304/23004

Abstract: The present invention provides a method of preparing epidermal growth factors in plants and transgenic plant seeds containing epidermal growth factors. The method provides an economical way to produce epidermal growth factors.

Abstract translation: 本发明提供了一种在植物中制备表皮生长因子并含有表皮生长因子的转基因植物种子的方法。 该方法提供了生产表皮生长因子的经济方法。

公开(公告)号：US20030096320A1

公开(公告)日：2003-05-22

申请号：US10260562

申请日：2002-10-01

Applicant: SemBioSys Genetics Inc.

Inventor： Maurice Moloney ,  Joseph Boothe ,  Gijs Van Rooijen

IPC: G01N033/53 ,  C07K014/415

CPC classification number: C07H21/00 ,  B01D15/08 ,  B01D15/3804 ,  B01D15/3809 ,  C01G11/003 ,  C07K1/22 ,  C07K14/415 ,  C07K16/065 ,  C08B1/00 ,  C12N9/6429 ,  C12Y304/21005

Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.

Abstract translation: 描述了从混合物中分离靶分子的方法。 该方法使用油体及其相关蛋白作为所需靶分子的选择性，非共价结合的亲和基质。 油体蛋白质可以遗传融合到对所需靶分子具有特异性的配体。 天然油体蛋白质也可以与油体蛋白质特异性配体如抗体或油体结合蛋白结合使用。 该方法允许由于油体和水溶液之间的密度差而使所需目标分子分离和回收。

公开(公告)号：US20030059910A1

公开(公告)日：2003-03-27

申请号：US10260960

申请日：2002-10-01

Applicant: SemBioSys Genetics Inc.

Inventor： Maurice Moloney ,  Joseph Boothe ,  Gijs Van Rooijen

IPC: C12N009/00 ,  A61K039/385 ,  A61K039/00 ,  C07K017/00 ,  C07K016/00 ,  C07K014/00 ,  A23J001/00 ,  C07K001/00

CPC classification number: C07H21/00 ,  B01D15/08 ,  B01D15/3804 ,  B01D15/3809 ,  C01G11/003 ,  C07K1/22 ,  C07K14/415 ,  C07K16/065 ,  C08B1/00 ,  C12N9/6429 ,  C12Y304/21005

Abstract: A method for the separation of a target molecule from a mixture is described. The method employs oil bodies and their associated proteins as affinity matrices for the selective, non-covalent binding of desired target molecules. The oil body proteins may be genetically fused to a ligand having specificity for the desired target molecule. Native oil body proteins can also be used in conjunction with an oil body protein specific ligand such as an antibody or an oil body binding protein. The method allows the separation and recovery of the desired target molecules due to the difference in densities between oil bodies and aqueous solutions.