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公开(公告)号:KR820000143B1
公开(公告)日:1982-02-20
申请号:KR780003706
申请日:1978-12-09
Applicant: TAKEDA PHARMACEUTICAL
Inventor: KATO M , TSUSIMA S , MATSUMOTO N
IPC: C07D501/18
Abstract: Title compds. II, as antibiotics with a broad spectrum activity, were prepd. by reaction of I (R1 = protected amino group) with acetylhalide or propionyl halide at -10≦̸C-50≦̸C, followed by conversion into the iminohalide, alcoholysis, and hydrolysis of the alkoxy imino compd. to I. (R2 = 3-oxobutyryl oxy group, 1-methyl-1H-tetrazol-5-yl thio group, or 1-(2-dimethyl amino ethyl)-1H-tetrazol-5-yl thio group).