公开(公告)号：WO2020027344A1

公开(公告)日：2020-02-06

申请号：PCT/JP2019/031284

申请日：2019-08-01

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： RATTI, Emiliangelo ,  ASGHARNEJAD, Mahnaz ,  BELFORT, Gabriel

IPC: A61K31/4545 ,  A61K45/06 ,  A61K9/00 ,  A61P25/24

Abstract: The present disclosure relates to methods of treating certain depressive disorders by administration of (4-benzyl-4-hydroxypiperidin-1-yl)(2,4'-bipyridin-3-yl)methanone or a pharmaceutically acceptable salt thereof or (2R)-1-((1-(4-(4-methyl-1H-pyrazol-1-yl)pyridin-3-yl)piperidin-4-yl)carbonyl)pyrrolidine-2-carbonitrile or a pharmaceutically acceptable salt thereof.