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公开(公告)号：KR790000165B1
公开(公告)日：1979-03-24
申请号：KR740003197
申请日：1974-07-27
Applicant: TAKEDA PHARMACEUTICAL IND CO L
Inventor： MEKURO KANJI , KUADA YUTAKA , SATO YOSHIAKI , HUKONO TAKESHI
Abstract: Thie-o (2,3-b) pyridinecarboxylic acid derivs. (I; R1, R4, R5 = H, alkyl, R2 = H, alkyl, halogen and alkylene, producing alkyl-substituted or non-substituted 5 or 6 membered ring by binding R1 and R2), useful as broad spectrum antibiotic to gram positive and gram negative bacteria, and their salts were prepd. by cyclization of II (R1, R2 given, R3 = alkyl, Z = H, carboxyl), hydrolysis if needed, and alkylation of the resulting I'(R1, R2, R4 give-).
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