公开(公告)号：US12285597B2

公开(公告)日：2025-04-29

申请号：US16949146

申请日：2020-10-15

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  Nichole Mercier

IPC: A61M60/50 ,  A61M60/135 ,  A61M60/422

Abstract: A circulatory support system includes an implantable blood pump including a housing, a rotor operable to pump blood from an inlet to an outlet, a stator, and at least two of the following: a current sensor, a rotor position sensor, an accelerometer, and a pressure sensor. The controller is connected to the sensors and includes a signal-processing module configured to receive, from each of the sensors, a data stream. The signal-processing module is also configured to filter the data streams received from the plurality of sensors, determine at least one of a pump operating parameter, a cardiac characteristic, and a pump control parameter based on at least two of the filtered data streams, and output the at least one of the pump operating parameter, the cardiac characteristic, and the pump control parameter to at least one of the operator interface module and the pump control module.

公开(公告)号：US20240055120A1

公开(公告)日：2024-02-15

申请号：US18383185

申请日：2023-10-24

Applicant: TC1 LLC

Inventor： Eric Lee ,  Daniel I. Harjes

IPC: G16H50/00 ,  G16H40/67 ,  G16H10/60

CPC classification number: G16H50/00 ,  G16H40/67 ,  G16H10/60

Abstract: Systems and methods for performing personalized cardiovascular analyses are provided. A method includes building, using a modeling and simulation computing device, a patient-specific model, storing, using the modeling and simulation computing device, the patient-specific model in a database, receiving, at the modeling and simulation computing device, remote monitoring data from at least one remote monitoring data source, and receiving, at the modeling and simulation computing device, clinical data from at least one clinical data source. The method further includes updating, using the modeling and simulation computing device, the patient-specific model using the remote monitoring data and the clinical data, performing, using the modeling and simulation computing device, at least one simulation on the updated patient-specific model, and outputting, from the modeling and simulation computing device, at least one output based on the at least one simulation.

公开(公告)号：US20230404421A1

公开(公告)日：2023-12-21

申请号：US18460185

申请日：2023-09-01

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  Kathryn B. Frederick ,  Eric Lee

IPC: A61B5/029 ,  A61B5/00 ,  A61M60/148 ,  A61M60/88 ,  A61M60/546 ,  A61M60/422 ,  A61M60/237 ,  A61M60/178 ,  A61M60/221 ,  A61M60/232 ,  A61M60/531

CPC classification number: A61B5/029 ,  A61B5/02405 ,  A61M60/148 ,  A61M60/88 ,  A61M60/546 ,  A61M60/422 ,  A61M60/237 ,  A61M60/178 ,  A61M60/221 ,  A61M60/232 ,  A61M60/531 ,  A61M2210/125 ,  A61M2205/3334 ,  A61M2205/3507 ,  A61B5/0031

Abstract: The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

公开(公告)号：US11065436B2

公开(公告)日：2021-07-20

申请号：US15938883

申请日：2018-03-28

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  John Freddy Hansen ,  Joseph C. Stark, III ,  Ghazal Anvar Mauro ,  Eric Lee ,  Justin A. Callaway ,  Onur Dur

IPC: A61N1/362 ,  A61M60/50 ,  A61B5/024 ,  A61B5/00 ,  A61N1/372 ,  A61M60/148 ,  A61M60/562 ,  A61M60/113 ,  A61M60/871

Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.

公开(公告)号：US20250121178A1

公开(公告)日：2025-04-17

申请号：US18962218

申请日：2024-11-27

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  Jeff Iudice ,  Joseph P. Sylvester, JR. ,  John Hai Nguyen ,  Michael Morado ,  Fabian Frigon Franco ,  Veera Venkata Jagadeesh Bobba ,  Soy Truong ,  Chanthy Luy ,  Jason Elledge ,  Lindsay Clough

IPC: A61M60/878 ,  A61M60/178

Abstract: Described herein is an implantable medical device including a housing, a header coupled to the housing, and a receptacle connector stack disposed in the header. The receptacle connector stack includes a plurality of electrical contacts and a plurality of wiper seals. Each electrical contact of the plurality of electrical contacts is separated by a corresponding wiper seal. A first sealing element is disposed at a proximal end of the receptacle connector stack and a second sealing element is disposed at a distal end of the receptacle connector stack. The sealing elements are mounted on respective seal housings. A third sealing element is disposed adjacent to the first sealing element and further proximal of the connector stack to restrict a bounce back effect caused by one or more of the plurality of wiper seals during insertion of a lead.

公开(公告)号：US12029535B2

公开(公告)日：2024-07-09

申请号：US17354976

申请日：2021-06-22

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  John Freddy Hansen ,  Joseph C. Stark, III ,  Ghazal Anvar Mauro ,  Eric Lee ,  Justin A. Callaway ,  Onur Dur

IPC: A61B5/024 ,  A61B5/00 ,  A61M60/148 ,  A61M60/178 ,  A61M60/221 ,  A61M60/232 ,  A61M60/237 ,  A61M60/515 ,  A61M60/569 ,  A61M60/816 ,  A61N1/362 ,  A61N1/372 ,  A61M60/113

CPC classification number: A61B5/02405 ,  A61B5/0031 ,  A61M60/148 ,  A61M60/178 ,  A61M60/221 ,  A61M60/232 ,  A61M60/237 ,  A61M60/515 ,  A61M60/569 ,  A61M60/816 ,  A61N1/3629 ,  A61N1/37288 ,  A61M60/113 ,  A61M2205/3334 ,  A61M2205/3507 ,  A61M2210/125

Abstract: The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.

公开(公告)号：US20240207600A1

公开(公告)日：2024-06-27

申请号：US18088079

申请日：2022-12-23

Applicant: TC1 LLC

Inventor： Daniel I. Harjes ,  Brian Kimball ,  Pritika Toutam ,  Fujian Qu

IPC: A61M60/515 ,  A61M60/178 ,  A61M60/216 ,  A61M60/422 ,  A61M60/538

CPC classification number: A61M60/515 ,  A61M60/178 ,  A61M60/216 ,  A61M60/422 ,  A61M60/538

Abstract: Circulatory support systems and related methods are disclosed in which a ventricular assist device is controlled based on cardiac activity monitored via cardiogram electrodes. A circulatory support system includes a ventricular assist device, cardiogram electrodes, and a controller. The controller processes a cardiogram signal generated via the cardiogram electrodes to determine one or more physiological parameters indicative of an activity level and/or cardiac cycle timing, determines at least one operating parameter for the ventricular assist device based on the one or more physiological parameters, and controls operation of the ventricular assist device in accordance with the at least one operating parameter.

公开(公告)号：US20240123131A1

公开(公告)日：2024-04-18

申请号：US18489158

申请日：2023-10-18

Applicant: TC1 LLC

Inventor： J. Freddy Hansen ,  Daniel I. Harjes

IPC: A61M1/16 ,  B01D63/04 ,  B01D69/08

CPC classification number: A61M1/1698 ,  A61M1/1625 ,  A61M1/1629 ,  B01D63/04 ,  B01D69/08 ,  A61M2202/0007 ,  A61M2202/0014 ,  A61M2202/0028 ,  A61M2202/0208 ,  A61M2202/0225 ,  A61M2206/12 ,  Y10S261/28

Abstract: An oxygenator and method for oxygenating blood. The oxygenator includes a housing, an oxygenation chamber, and elongated gas permeable conduits that extend across the oxygenation chamber. The blood flow enters and contacts with exterior surfaces of the conduits and exits the oxygenator to transfer of oxygen from within the conduits to the blood flow and transfer carbon dioxide from the blood flow into the elongated gas permeable conduits. The housing includes a gas inlet and is configured to distribute a gas flow received through the gas inlet to the elongated gas permeable conduits so as to a first portion of the gas flow flows through a first set of the elongated gas permeable conduits in a first direction and a second portion of the gas flow flows through a second set of the elongated gas permeable conduits in a second direction that is opposite to the first direction.

公开(公告)号：US11837364B2

公开(公告)日：2023-12-05

申请号：US17118951

申请日：2020-12-11

Applicant: TC1 LLC

Inventor： Eric Lee ,  Daniel I. Harjes

IPC: G16H50/00 ,  G16H40/67 ,  G16H10/60

CPC classification number: G16H50/00 ,  G16H10/60 ,  G16H40/67

Abstract: Systems and methods for performing personalized cardiovascular analyses are provided. A method includes building, using a modeling and simulation computing device, a patient-specific model, storing, using the modeling and simulation computing device, the patient-specific model in a database, receiving, at the modeling and simulation computing device, remote monitoring data from at least one remote monitoring data source, and receiving, at the modeling and simulation computing device, clinical data from at least one clinical data source. The method further includes updating, using the modeling and simulation computing device, the patient-specific model using the remote monitoring data and the clinical data, performing, using the modeling and simulation computing device, at least one simulation on the updated patient-specific model, and outputting, from the modeling and simulation computing device, at least one output based on the at least one simulation.

公开(公告)号：US20210384771A1

公开(公告)日：2021-12-09

申请号：US17341818

申请日：2021-06-08

Applicant: TC1 LLC

Inventor： John Freddy Hansen ,  Russell Anderson ,  Daniel I. Harjes ,  Alexander Baval ,  Jeffrey Iudice

IPC: H02J50/12 ,  H02J50/00

Abstract: A resonator for use in a wireless power transfer system is provided. The resonator includes a core including a front surface, a back surface, and an annular sidewall extending between the front surface and the back surface, wherein an annular groove is defined in the front surface and surrounds a post, and wherein a cavity is defined in the back surface, the post and the cavity aligned with a longitudinal axis of the core. The resonator further includes a coil element disposed within the annular groove.