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1.发明申请SOLUBLE ALKYL [5-[AMINO(PHENYL)METHYL]-1H-BENZIMIDAZOL-2-YL]CARBAMATE ANTHELMINTICS 审中-公开可溶性烷基[5- [氨基（苯基）甲基] -1H-苯并咪唑-2-基]碳酸酯类化合物
公开(公告)号：WO1993023037A1
公开(公告)日：1993-11-25
申请号：PCT/US1993004109
申请日：1993-05-03
Inventor： THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ... , TOWNSEND, Leroy, B. , WISE, Dean, S. , RAM, Siya
IPC: A61K31/415
CPC classification number: C07D235/32
Abstract: Soluble alkyl [5-[amino(phenyl)methyl]-2H-benzimidazol-2-yl]carbamates, their enantiomorphic forms, and acid addition salts thereof are well absorbed and possess curative anthelmintic activity, especially against filarial worms, when administered orally or parenterally. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating helminth infections in mammals are also disclosed, together with methods of synthesis.
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2.发明公开SOLUBLE ALKYL 5- AMINO(PHENYL)METHYL]-1H-BENZIMIDAZOL-2-YL]CARBAMATE ANTHELMINTICS 失效LÖSLICHEALKYL-（5-氨基（苯基）甲基）-1H-苯并咪唑-2-基 - 碳酸酯类化合物。
公开(公告)号：EP0639974A1
公开(公告)日：1995-03-01
申请号：EP93910966.0
申请日：1993-05-03
Inventor： TOWNSEND, Leroy, B. , WISE, Dean, S. , RAM, Siya
IPC: C07D235
CPC classification number: C07D235/32
Abstract: Soluble alkyl [5-[amino(phenyl)methyl]-2H-benzimidazol-2-yl]carbamates, their enantiomorphic forms, and acid addition salts thereof are well absorbed and possess curative anthelmintic activity, especially against filarial worms, when administered orally or parenterally. Pharmaceutical compositions containing the compounds and methods of employing the compounds in methods of treating helminth infections in mammals are also disclosed, together with methods of synthesis.
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