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1.
公开(公告)号:WO2023285922A1
公开(公告)日:2023-01-19
申请号:PCT/IB2022/056234
申请日:2022-07-06
Applicant: THE CATHOLIC UNIVERSITY OF AMERICA
Inventor: RAO, Venigalla B. , BATRA, Himanshu
IPC: C12N15/86 , C07K14/005 , C12N7/00 , C12N5/0783
Abstract: Described is an engineered viral particle programmed with T cell targeting specificity. The viral particles comprise: at least one viral vector, such as bacteriophage T4; and at least one CD4-binding protein displayed on the surface of the viral vector. Also described is a method of reactivate latent HIV-1 and cure patient with HIV-1 infection, using such an engineered viral particle.
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2.
公开(公告)号:EP4370696A1
公开(公告)日:2024-05-22
申请号:EP22841572.5
申请日:2022-07-06
Applicant: THE CATHOLIC UNIVERSITY OF AMERICA
Inventor: RAO, Venigalla B. , BATRA, Himanshu
IPC: C12N15/86 , C07K14/005 , C12N7/00 , C12N5/0783
CPC classification number: C12N15/86 , C12N2795/1014320130101 , C07K14/005 , C12N2740/1612220130101 , C12N2795/1014520130101 , C12N5/0636 , C12N2510/0020130101
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