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公开(公告)号：US20190321821A1
公开(公告)日：2019-10-24
申请号：US16168020
申请日：2018-10-23
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Sarkis Babikian , Guann-Pyng Li
Abstract: A microfluidic component package that is readily integratable within a microfluidic system.
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公开(公告)号：US20180311468A1
公开(公告)日：2018-11-01
申请号：US15963851
申请日：2018-04-26
Applicant: The Regents of the University of California
Inventor： Ralph V. Clayman , Kamaljot S. Kaler , Jaime Landman , Michael J. Klopfer , Guann-Pyng Li
Abstract: Provided herein is a load sensing device. In one embodiment, the device comprises a load cell adapted to receive a force, an input/output interface, and an adjustable attachment mechanism adapted to reversibly attach a surgical device. In another embodiment, the load cell detects the amount of force applied during the deployment of the surgical device in a patient and outputs a force value representative thereof via the input/output interface. Also provided herein are methods of making and using load sensing devices.
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公开(公告)号：US10033084B2
公开(公告)日：2018-07-24
申请号：US14937811
申请日：2015-11-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Guann-Pyng Li , Yu Guo
Abstract: A cavity resonator or filter constructed on electromagnetic bandgap (EBG) substrate is provided that includes an external controlling assemble having a plurality of components configured to change a working frequency of the cavity resonator or filter. A dual-band bandpass filter is provided that includes two or more single band filters on a single EBG substrate and an external controlling assemble having a plurality of components configured to change a working frequency of the cavity resonator or filter.
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公开(公告)号：US20220126066A1
公开(公告)日：2022-04-28
申请号：US17570776
申请日：2022-01-07
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Ralph V. Clayman , Kamaljot S. Kaler , Jamie Landman , Michael John Klopfer , Guann-Pyng Li
Abstract: Various embodiments herein comprise a handheld load sensing device. In one embodiment, the device comprises a force sensor (e.g., a mechanical spring or an electromechanical load cell) adapted to receive a force, an input/output interface, and an adjustable attachment mechanism adapted to reversibly attach a surgical device. In another embodiment, the force sensor detects the amount of force applied during the deployment of the surgical device in a patient and outputs a force value representative thereof via the input/output interface. Also provided herein are methods of making and using load sensing devices.
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公开(公告)号：US20200253493A1
公开(公告)日：2020-08-13
申请号：US16639366
申请日：2018-08-16
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Sarkis Babikian , Guann-Pyng Li
Abstract: A miniature wireless pressure sensor has an inductor and a capacitor. The inductor and the capacitor form a L-C resonator with a resonate frequency. The inductor's inductance is affected by a slidable electro-magnetic element. When an outside pressure is applied onto the element, it causes the element to move and such movement changes the inductance of the inductor. Because of that, the resonate frequency is changed. Therefore, the change in resonate frequency indicates a change in the outside pressure. The L-C resonator is calibrated to correlate with the outside pressure. Such a miniature wireless pressure sensor facilitates the monitoring of physiological pressure in different part of human body such as eyes and cranium.
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Patent Agency Ranking
公开(公告)号：US10471276B2
公开(公告)日：2019-11-12
申请号：US15766802
申请日：2016-10-07
Applicant: The Regents of the University of California
Inventor： William Beckner , John A. Ives , Mark Bachman , Guann-Pyng Li
Abstract: An apparatus and method utilizes photonics, particularly lasers, and biometric feedback for physiological and neurological stimulation. While many areas of the body are candidates, such laser stimulation is particularly directed to the outer ear. Lasers positioned over the ear stimulate targets on the outer ear for pain and stress management and regulation of the autonomic nervous system to affect symptoms and clinical conditions. Laser positioning, wavelength, aiming, focus, power, power density, timing, and sequencing are managed and modified dynamically in real time to effect a personalized and effective treatment protocol.
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7.发明申请CELL IDENTIFICATION SYSTEMS AND METHODS USING FUNCTIONALIZED MICROPALLET ARRAYS 审中-公开细胞鉴定系统和使用功能化微阵列阵列的方法公开(公告)号：US20130337473A1
公开(公告)日：2013-12-19
申请号：US13888299
申请日：2013-05-06
Applicant: The Regents of the University of California
Inventor： Edward L. Nelson , Trisha M. Westerhof , Mark Bachman , Guann-Pyng Li
IPC: G01N33/574
CPC classification number: G01N33/574 , G01N33/56966 , G01N33/56972 , G01N33/56977 , G01N33/57438
Abstract: Cell identification systems and methods using micropallet arrays are disclosed. According to one embodiment, a cell identification strategy involves detecting the expression patterns of markers that are expressed on cells to uniquely identify different cell populations within heterogeneous mixtures of cells. The cell markers may be on the cell surface or intracellular in location. The cell markers are interrogated using monoclonal antibodies (mAbs) that are directly conjugated to flourophores. The mAb-flourophore conjugates are used to detect the presence or absence and relative level of expression of each of the cell markers using laser scanning confocal microscopy.
Abstract translation: 公开了使用微孔阵列的细胞鉴定系统和方法。 根据一个实施方案，细胞鉴定策略涉及检测在细胞上表达的标志物的表达模式以唯一地鉴定细胞异种混合物内的不同细胞群。 细胞标志物可以在细胞表面上或细胞内的位置。 使用直接与荧光体缀合的单克隆抗体（mAb）来询问细胞标记物。 使用激光扫描共聚焦显微镜，使用mAb-荧光共轭物来检测每种细胞标记物的存在或不存在和相对的表达水平。
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公开(公告)号：US20180280721A1
公开(公告)日：2018-10-04
申请号：US15766802
申请日：2016-10-07
Applicant: The Regents of the University of California
Inventor： William Beckner , John A. Ives , Mark Bachman , Guann-Pyng Li
CPC classification number: A61N5/0619 , A61B5/021 , A61B5/02416 , A61B5/0532 , A61B5/0816 , A61B5/4836 , A61H39/02 , A61N5/0622 , A61N2005/0605 , A61N2005/0647 , A61N2005/067
Abstract: An apparatus and method utilizes photonics, particularly lasers, and biometric feedback for physiological and neurological stimulation. While many areas of the body are candidates, such laser stimulation is particularly directed to the outer ear. Lasers positioned over the ear stimulate targets on the outer ear for pain and stress management and regulation of the autonomic nervous system to affect symptoms and clinical conditions. Laser positioning, wavelength, aiming, focus, power, power density, timing, and sequencing are managed and modified dynamically in real time to effect a personalized and effective treatment protocol.
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公开(公告)号：US20170301493A1
公开(公告)日：2017-10-19
申请号：US15458444
申请日：2017-03-14
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Mark Bachman , Guann-Pyng Li , Yang Zhang , Minfeng Wang
CPC classification number: H01H50/32 , B81B3/0054 , B81B2201/016 , H01H1/0036 , H01H50/005 , H01H50/44 , H01H50/58 , H01H2001/0042
Abstract: Micro-electromagnetically actuated latched miniature relay switches formed from laminate layers comprising a spring and magnet, electromagnetic coils, magnetic latching material, and transmission line with contacts. Preferably the miniature relay switches transmit up to about 50 W of DC or AC line power, and carry up to about 10 A of load current, with an overall volume of less than about 100 mm3. In addition to switching large power, the device preferably requires less than 3 V to actuate, and has a latching feature that retains the switch state after actuation without the need for external applied voltage or current.
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10.发明申请OPERATION FREQUENCY BAND CUSTOMIZABLE AND FREQUENCY TUNABLE FILTERS WITH EBG SUBSTRATES 审中-公开带有EBG基板的工作频带可定制和频率可调滤波器公开(公告)号：US20160134253A1
公开(公告)日：2016-05-12
申请号：US14937811
申请日：2015-11-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Guann-Pyng Li , Yu Guo
CPC classification number: H01P7/065 , H01P1/2005
Abstract: A cavity resonator or filter constructed on electromagnetic bandgap (EBG) substrate is provided that includes an external controlling assemble having a plurality of components configured to change a working frequency of the cavity resonator or filter. A dual-band bandpass filter is provided that includes two or more single band filters on a single EBG substrate and an external controlling assemble having a plurality of components configured to change a working frequency of the cavity resonator or filter.
Abstract translation: 提供一种构造在电磁带隙（EBG）衬底上的空腔谐振器或滤波器，其包括具有多个组件的外部控制组合，该多个组件被配置为改变空腔谐振器或滤波器的工作频率。 提供了一种双频带通滤波器，其在单个EBG衬底上包括两个或更多个单频带滤波器，以及外部控制组合，其具有被配置为改变空腔谐振器或滤波器的工作频率的多个分量。
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