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公开(公告)号：US11839585B2
公开(公告)日：2023-12-12
申请号：US17898182
申请日：2022-08-29
Applicant: The Regents of the University of California
Inventor： Michael Austin Johnson , Jason Adams , Jean-Pierre Delplanque , Justin Koos , Gregory Rehm
CPC classification number: A61H31/00 , A61B5/0022 , A61B5/7203 , A61B5/7264 , A61B5/7282 , A61B5/742 , A61B5/7405 , A61H2201/5023 , A61H2201/5087
Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.
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公开(公告)号：US20230355866A1
公开(公告)日：2023-11-09
申请号：US18078857
申请日：2022-12-09
Applicant: The Regents of the University of California , Government of the United States as represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Lucas Paul Neff , Timothy Williams
CPC classification number: A61M5/142 , A61M25/10184 , A61M2005/14208 , A61M25/1011 , A61M25/10182 , A61M2205/05 , A61M2205/3331 , A61M2205/3584 , A61M2210/127 , A61M2230/06 , A61M2230/205 , A61M2230/208 , A61M2230/30 , A61M2230/42 , A61M2230/50
Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta. The system may also include one or more sensors for measuring physiological information indicative of blood flow through the aorta, and a non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the one or more sensors, cause the processor to compare the measured physiological information with a target physiological range associated with blood flow through the aorta such that the catheter controller unit automatically adjusts expansion and contraction of the expandable aortic blood flow regulation device to adjust an amount of blood flow through the aorta if the measured physiological information falls outside the target physiological range.
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公开(公告)号：US11596411B2
公开(公告)日：2023-03-07
申请号：US16657588
申请日：2019-10-18
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , Government of the United States as Represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Timothy K. Williams , Lucas Paul Neff
Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device. The system further may include non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the sensors, cause the processor to estimate aortic blood flow based on the measured blood pressures and corresponding waveforms, compare the estimated aortic blood flow with a target aortic blood flow range, generate an alert if the estimated aortic blood flow falls outside the target aortic blood flow range, and cause the catheter controller unit to adjust expansion and contraction of the expandable device to adjust an amount of blood flow through the aorta if the estimated aortic blood flow falls outside the target aortic blood flow range.
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公开(公告)号：US20200046364A1
公开(公告)日：2020-02-13
申请号：US16657588
申请日：2019-10-18
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , Government of the United States as Represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Timothy K. Williams , Lucas Paul Neff
Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device. The system further may include non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the sensors, cause the processor to estimate aortic blood flow based on the measured blood pressures and corresponding waveforms, compare the estimated aortic blood flow with a target aortic blood flow range, generate an alert if the estimated aortic blood flow falls outside the target aortic blood flow range, and cause the catheter controller unit to adjust expansion and contraction of the expandable device to adjust an amount of blood flow through the aorta if the estimated aortic blood flow falls outside the target aortic blood flow range.
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公开(公告)号：US12290659B2
公开(公告)日：2025-05-06
申请号：US18078857
申请日：2022-12-09
Applicant: The Regents of the University of California , Government of the United States as represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Lucas Paul Neff , Timothy Williams
Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta. The system may also include one or more sensors for measuring physiological information indicative of blood flow through the aorta, and a non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the one or more sensors, cause the processor to compare the measured physiological information with a target physiological range associated with blood flow through the aorta such that the catheter controller unit automatically adjusts expansion and contraction of the expandable aortic blood flow regulation device to adjust an amount of blood flow through the aorta if the measured physiological information falls outside the target physiological range.
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Patent Agency Ranking
公开(公告)号：US20200054520A1
公开(公告)日：2020-02-20
申请号：US16348795
申请日：2017-11-10
Applicant: The Regents of the University of California
Inventor： Michael Austin Johnson , Jason Adams , Jean-Pierre Delplanque , Justin Koos , Gregory Rehm
Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.
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公开(公告)号：US20200038566A1
公开(公告)日：2020-02-06
申请号：US16507938
申请日：2019-07-10
Inventor： Michael Austin Johnson , Lucas Paul Neff , Timothy Williams
Abstract: Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta. The system may also include one or more sensors for measuring physiological information indicative of blood flow through the aorta, and a non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the one or more sensors, cause the processor to compare the measured physiological information with a target physiological range associated with blood flow through the aorta such that the catheter controller unit automatically adjusts expansion and contraction of the expandable aortic blood flow regulation device to adjust an amount of blood flow through the aorta if the measured physiological information falls outside the target physiological range.
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公开(公告)号：US20230414220A1
公开(公告)日：2023-12-28
申请号：US18160248
申请日：2023-01-26
Applicant: The Regents of the University of California , Government of the United States as Represented by the Secretary of the Air Force
Inventor： Michael Austin Johnson , Timothy K. Williams , Lucas Paul Neff
CPC classification number: A61B17/12036 , A61M25/10182 , A61B17/12109 , A61B17/12136 , A61B2017/00022
Abstract: Systems and methods for partial aortic occlusion are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient, and a catheter controller unit that causes the device to expand and contract to restrict blood flow through the aorta. The system also may include sensors for measuring blood pressure distal and proximal to the expandable device. The system further may include non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the sensors, cause the processor to estimate aortic blood flow based on the measured blood pressures and corresponding waveforms, compare the estimated aortic blood flow with a target aortic blood flow range, generate an alert if the estimated aortic blood flow falls outside the target aortic blood flow range, and cause the catheter controller unit to adjust expansion and contraction of the expandable device to adjust an amount of blood flow through the aorta if the estimated aortic blood flow falls outside the target aortic blood flow range.
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公开(公告)号：US20180147375A1
公开(公告)日：2018-05-31
申请号：US15578212
申请日：2016-06-02
Applicant: The Regents of the University of California
Inventor： Michael Austin Johnson , Justin Koos
CPC classification number: A61M16/0051 , A61B5/0816 , A61B5/087 , A61B5/091 , A61M16/0078 , A61M16/0084 , A61M16/024 , A61M16/0816 , A61M16/208 , A61M2016/0027 , A61M2016/0039 , A61M2016/0042 , A61M2016/1025 , A61M2016/103 , A61M2205/15 , A61M2205/18 , A61M2205/3306 , A61M2205/3334 , A61M2205/3368 , A61M2205/3375 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/505 , A61M2205/507 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6009 , A61M2205/6018 , A61M2205/6081 , A61M2230/00 , A61M2230/42 , A61M2230/432 , A61M2230/435 , A61M2230/005
Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter measuring characteristics of the airflows. A user may provide a controller with patient size information via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. If the measured airflow characteristics fall outside an acceptable range, the controller may cause a sensory alarm to alert the user. The device may work within a network of devices and user interfaces. The device may include a variety of sensors including pressure, CO2, O2, and temperature sensors. If the measurements of these sensors fall outside an acceptable range, the controller may cause a sensory alarm to alert the user.
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公开(公告)号：US20240082104A1
公开(公告)日：2024-03-14
申请号：US18388711
申请日：2023-11-10
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Michael Austin Johnson , Jason Adams , Jean-Pierre Delplanque , Justin Koos , Gregory Rehm
CPC classification number: A61H31/00 , A61B5/0022 , A61B5/7203 , A61B5/7264 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61H2201/5023 , A61H2201/5087
Abstract: Resuscitation and ventilation monitoring devices are provided. A device includes an inlet in fluid communication with airflows exchanged with lungs of a patient and an airflow meter for measuring characteristics of the airflows. A user may provide a controller with patient information, e.g., height, weight, gender, or age, via a measurement selector, enabling the controller to determine acceptable ranges of measured airflow characteristics. The device may determine a current mode of ventilation and associated ventilator settings based on the measured airflow characteristics. The device may also identify and filter out artifacts present in the ventilation signal, and determine whether a respiratory failure phenotype is present in the ventilation. If the current mode of ventilation and associated ventilator settings fall outside an acceptable range, the ventilation is classified as off-target and the controller may cause a sensory alarm to alert the user. The device may suggest a corrective action based on the type of off-target ventilation detected. The device may also continuously analyze ventilation to determine changes in lung compliance over time and to identify pathological changes over time. The device may work within a network of devices and user interfaces via wired or wireless communication, and is not restricted to or dependent on the type of ventilatory device with which a patient is being supported.
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