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公开(公告)号：KR20180043200A
公开(公告)日：2018-04-27
申请号：KR20177033605
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , KUBOTA YUKO , YAMAMOTO MASASHI , NISHIMURA YUTAKA , MASUDA TOMOHIDE , TSUTSUI HIDEYUKI , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07D413/04 , A61K31/17 , A61K31/505 , A61K31/5377 , A61P35/00 , C07D239/34 , C07D239/47
CPC classification number: A61K31/17 , A61K31/4406 , A61K31/4409 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/50 , A61K31/506 , A61K31/513 , A61K31/5377 , C07C275/34 , C07D213/30 , C07D213/65 , C07D213/74 , C07D237/14 , C07D239/34 , C07D239/47 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14
Abstract: 본발명은디스코이딘도메인수용체 1에대해서저해활성을갖는화합물을제공하는것을목적으로하고있다. 본발명은하기식으로대표되는요소유도체또는그 약리학적으로허용되는염을제공한다.
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公开(公告)号：KR20180043199A
公开(公告)日：2018-04-27
申请号：KR20177033032
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , YAMAMOTO MASASHI , KUBOTA YUKO , TSUTSUI HIDEYUKI , MASUDA TOMOHIDE , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07D213/30 , A61K31/17 , A61K31/4409 , A61P35/00 , C07C275/30 , C07C275/32 , C07C275/34
CPC classification number: A61K31/17 , A61K31/192 , A61K31/235 , A61K31/337 , A61K31/44 , A61K31/4406 , A61K31/4409 , A61K31/4465 , A61K31/455 , A61K31/495 , A61K31/506 , C07C275/30 , C07C275/32 , C07C275/34 , C07D211/46 , C07D213/30 , C07D213/68 , C07D213/81 , C07D213/82 , C07D305/08 , C07D403/04
Abstract: 본발명은디스코이딘도메인수용체 1에대하여저해활성을갖는화합물을제공하는것을목적으로하고있다. 본발명은하기식으로대표되는요소유도체또는그 약리학적으로허용되는염을제공한다.
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公开(公告)号：ES2764731T3
公开(公告)日：2020-06-04
申请号：ES16841903
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , KUBOTA YUKO , YAMAMOTO MASASHI , NISHIMURA YUTAKA , MASUDA TOMOHIDE , TSUTSUI HIDEYUKI , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C275/34 , A61K31/17 , A61K31/4406 , A61K31/4409 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/50 , A61K31/506 , A61K31/513 , A61K31/5377 , A61P35/00 , A61P43/00 , C07D213/30 , C07D213/65 , C07D213/74 , C07D237/14 , C07D239/34 , C07D239/47 , C07D401/04
Abstract: Derivado de urea representado por la fórmula (I): **(Ver fórmula)** en la que, R1 es trifluorometilo, trifluorometoxi o pentafluorosulfanilo; cada R2 es independientemente un átomo de hidrógeno o metilo que está, opcionalmente, sustituido con un hidroxilo o un heterociclilo saturado que tiene de cuatro a seis átomos formadores de anillo; R3 es un átomo de hidrógeno, un átomo de halógeno, un alquilo C1-C3, un heterociclilo saturado que tiene de cuatro a seis átomos formadores de anillo y que, opcionalmente, tiene un grupo oxo, o R5O-; R4 es fenilo, piridilo, piridazinilo o pirimidinilo, estando dichos fenilo, piridilo, piridazinilo o pirimidinilo, opcionalmente, sustituidos con un R6; m y n son independientemente 0 o 1; R5 es alquilo C1-C3 o heterociclilo saturado que tiene de cuatro a seis átomos formadores de anillo (siempre que si se incluye un átomo de nitrógeno en los átomos formadores de anillo de R5, dicho átomo de nitrógeno está, opcionalmente, sustituido con acetilo); R6 es carbamoílo, fenilo, heteroarilo que tiene cinco o seis átomos formadores de anillo, heterociclilo saturado que tiene cuatro a seis átomos formadores de anillo, o (R7)R8N-; y cada uno de R7 y R8 es independientemente un átomo de hidrógeno, o alquilo C1-C3 que está, opcionalmente, sustituido por hidroxilo (excluyendo los casos en que m y n son 0 y R4 es fenilo o piridilo, y dichos fenilo o piridilo están sustituidos por carbamoílo) o una sal farmacéuticamente aceptable del mismo.
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公开(公告)号：HK1248209A1
公开(公告)日：2018-10-12
申请号：HK18107600
申请日：2018-06-12
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , KUBOTA YUKO , YAMAMOTO MASASHI , NISHIMURA YUTAKA , MASUDA TOMOHIDE , TSUTSUI HIDEYUKI , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C20060101 , A61K20060101 , A61P20060101 , C07D20060101
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公开(公告)号：AU2016316223A1
公开(公告)日：2018-02-22
申请号：AU2016316223
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , YAMAMOTO MASASHI , KUBOTA YUKO , TSUTSUI HIDEYUKI , MASUDA TOMOHIDE , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C275/34 , A61K31/17 , A61K31/192 , A61K31/235 , A61K31/337 , A61K31/44 , A61K31/4406 , A61K31/4409 , A61K31/4465 , A61K31/455 , A61K31/495 , A61K31/506 , A61P35/00 , A61P35/02 , A61P43/00 , C07C275/30 , C07C275/32 , C07D211/46 , C07D213/30 , C07D213/68 , C07D213/81 , C07D213/82 , C07D305/08 , C07D403/04
Abstract: The purpose of the present invention is to provide a compound having inhibitory activity with respect to the discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula below or a pharmacologically acceptable salt thereof.
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Patent Agency Ranking
公开(公告)号：AU2016317531A1
公开(公告)日：2018-02-22
申请号：AU2016317531
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , KUBOTA YUKO , YAMAMOTO MASASHI , NISHIMURA YUTAKA , MASUDA TOMOHIDE , TSUTSUI HIDEYUKI , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C275/34 , A61K31/17 , A61K31/4406 , A61K31/4409 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/50 , A61K31/506 , A61K31/513 , A61K31/5377 , A61P35/00 , A61P43/00 , C07D213/30 , C07D213/65 , C07D213/74 , C07D237/14 , C07D239/34 , C07D239/47 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14
Abstract: The purpose of the present invention is to provide a compound having inhibitory activity with respect to the discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula below or a pharmacologically acceptable salt thereof.
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公开(公告)号：CA2992024A1
公开(公告)日：2017-03-09
申请号：CA2992024
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , YAMAMOTO MASASHI , KUBOTA YUKO , TSUTSUI HIDEYUKI , MASUDA TOMOHIDE , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C275/34 , A61K31/17 , A61K31/192 , A61K31/235 , A61K31/337 , A61K31/44 , A61K31/4406 , A61K31/4409 , A61K31/4465 , A61K31/455 , A61K31/495 , A61K31/506 , A61P35/00 , A61P35/02 , A61P43/00 , C07C275/30 , C07C275/32 , C07D211/46 , C07D213/30 , C07D213/68 , C07D213/81 , C07D213/82 , C07D305/08 , C07D403/04
Abstract: The purpose of the present invention is to provide a compound having inhibitory activity with respect to the discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula below or a pharmacologically acceptable salt thereof.
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公开(公告)号：CA2962730A1
公开(公告)日：2016-04-07
申请号：CA2962730
申请日：2015-09-30
Applicant: UNIV OSAKA , TORAY INDUSTRIES
Inventor： MATUBAYASI NOBUYUKI , MASUDA TOMOHIDE , TANIMURA RYUJI
IPC: G06F19/12
Abstract: The purpose of the present invention is to provide a device, a method, a program, and a recording medium with the program recorded thereon, for calculating, quickly and with high precision, differences in free energy between different molecules. To achieve this purpose, in this device, method, program, and recording medium with the program recorded thereon, ?G is calculated on the basis of mathematical formula (1).
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公开(公告)号：MY161947A
公开(公告)日：2017-05-15
申请号：MYPI2012001105
申请日：2010-09-07
Applicant: TORAY INDUSTRIES
Inventor： AOYAMA SHIGERU , SHIOMI ATSUSHI , MASUDA TOMOHIDE , TAKAHASHI KOZO
Abstract: PROVIDED IS A POLYESTER FILM WHICH HIGHLY SATISFACTORILY HIGH MOIST-HEAT RESISTANCE, AND OTHER PROPERTIES (IN PARTICULAR, ULTRAVIOLET LIGHT RESISTANCE, LIGHT-REFLECTING PROPERTIES, ETC.) OVER A LONG PERIOD. ALSO PROVIDED ARE: A SOLAR-CELL BACK SHEET WHICH COMPRISES THE POLYESTER FILM AND HENCE HAS HIGH DURABILITY: AND A SOLAR CELL INCLUDING THE BACK SHEET. THE POLYESTER FILM HAS A LAMINATE STRUCTURE COMPRISING A POLYESTER LAYER (LAYER P1) CONTAINING A CRYSTALLINE POLYESTER AND INORGANIC PARTICLES AND A POLYESTER LAYER (LAYER P2) CONTAINING A CRYSTALLINE POLYESTER, INORGANIC PARTICLES, AND AN ANTIHYDOLYSIS SEGMENT, WHEREIN THE CONTENT (WA2) OF THE INORGANIC PARTICLES IN THE LAYER P2 IS AT LEAST 10 MASS% OF THE LAYER P2, THE DIFFERENCE BETWEEN THE CONTENT (WA2) (MASS%) OF THE INORGANIC PARTICLES IN THE LAYER P1, WA2-WA1, IS 5 TO 25 MASS%, AND THE CONTENT (WB2) OF THE ANTIHYDROLYSIS SEGMENT IN THE LAYER P2 IS 0.02 TO 1.5 MASS% OF THE LAYER P2.
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公开(公告)号：CA2991697A1
公开(公告)日：2017-03-09
申请号：CA2991697
申请日：2016-08-31
Applicant: TORAY INDUSTRIES
Inventor： NISHIO YUKIHIRO , KUBOTA YUKO , YAMAMOTO MASASHI , NISHIMURA YUTAKA , MASUDA TOMOHIDE , TSUTSUI HIDEYUKI , OKIMURA KEIICHI , UDAGAWA SYUJI , KAINO MIE , MEGURO HIROYUKI , SEKIYA YUMIKO
IPC: C07C275/34 , A61K31/17 , A61K31/4406 , A61K31/4409 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/50 , A61K31/506 , A61K31/513 , A61K31/5377 , A61P35/00 , A61P43/00 , C07D213/30 , C07D213/65 , C07D213/74 , C07D237/14 , C07D239/34 , C07D239/47 , C07D401/04 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14
Abstract: The purpose of the present invention is to provide a compound having inhibitory activity with respect to the discoidin domain receptor 1. The present invention provides a urea derivative represented by the formula below or a pharmacologically acceptable salt thereof.
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