公开(公告)号：DE3483245D1

公开(公告)日：1990-10-25

申请号：DE3483245

申请日：1984-09-12

Applicant: TOSOH CORP

Inventor： IWATA KAZUO ,  TAKEMATSU TETSUO ,  NONAKA YUKI ,  NAKANISHI AKIRA ,  MORINAKA HIDEO ,  TSUZUKI KENJI ,  MURAKAMI MITSUYUKI ,  UOTANI TAKESHI

IPC: A61K31/27 ,  A01N47/18 ,  A01N47/22 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4418 ,  A61K31/47 ,  A61P31/00 ,  A61P31/04 ,  A61P31/10 ,  C07D213/75 ,  C07D215/22 ,  C07D401/12 ,  C07D405/12

Abstract: Described is the use of carbamate or thiocarbamate derivatives having the general formula (I): X - O - @ - @ - W (I) where X is 2-naphthyl, 5-indanyl, 5,6,7,8-tetrahydro-2-naphthyl, 1,4-methano-1,2,3,4-tetrahydro-6-naphthyl, 1,4-ethano-1,2,3,4-tetrahydro-6-naphthyl, 2-quinolyl, or a phenyl group having one or two of the same or different substituents selected from the group of halogen atom, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, halogenated lower alkyl, lower alkylthio, lower alkylsulfonyl, lower alkylamino, nitro, and methylenedioxy; Y is an oxygen atom or a sulfur atom; Z is a lower alkyl group; W is pyridyl group having one or two of the same substituents selected from the group of lower alkyl, lower alkoxy, lower alkenyloxy, and lower alkylamino, for the preparation of compositions for the treatment of fungal infections.