Abstract:
PROBLEM TO BE SOLVED: To provide a medicine having the practically same pharmacodynamic profiles of cetirizine and pseudoephedrine as those in a medicine administration type containing the same amount of cetirizine and pseudoephedrine discretely as the discrete active ingredients. SOLUTION: The tablet comprises at least two discrete segments, one of which mainly contains the cetirizine as the active ingredient and the other second segment mainly contains the pseudoephedrine as the active ingredient, wherein the pseudoephedrine segment and the cetirizine segment contact directly and their interfacial surface area is 2 . COPYRIGHT: (C)2007,JPO&INPIT
Abstract:
PROBLEM TO BE SOLVED: To provide a stable pharmaceutical composition for oral administration of an active compound.SOLUTION: The pharmaceutical composition for oral administration contains at least two separate formulations. A first formulation, which contains the active compound selected from 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids and their amides, does not contain polyols having a molecular weight of less than 950 in a molar ratio between the polyols and the active compound represented by formula I above 10. Lactose is an exception. A second formulation contains one or more solid polyols of a molecular weight of less than 3,000 and is free of any drug. The composition is a dry syrup composition.
Abstract:
PROBLEM TO BE SOLVED: To provide a stable pharmaceutical composition for oral administration of an active compound.SOLUTION: The oral drug composition includes at least two different formulations, or a first formulation including an active compound selected from 2-[4-(diphenylmethyl)-1-pyperadinyl]-acetic acid and amides thereof, the first formulation not including, except lactose, a polyol having a molecular weight of less than 950 in a mole ratio exceeding 10 of the active compound of formula I; and a second formulation including one or more solid polyols having a molecular weight of less than 3,000, the second formulation including no medicinal substances. The composition has a form of dry syrup.
Abstract:
PROBLEM TO BE SOLVED: To provide a stable pharmaceutical composition for oral administration of an active compound. SOLUTION: The pharmaceutical composition for oral administration contains at least two separate formulations. A first formulation, which contains the active component selected from 2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acids and their amides, does not contain polyols having a molecular weight of less than 950 in a molar ratio between the polyols and the active compound represented by formula I above 10. Lactose is an exception. A second formulation contains one or more solid polyols of a molecular weight of less than 3,000 and is free of any drug. The composition is a dry syrup composition. COPYRIGHT: (C)2010,JPO&INPIT
Abstract:
The present invention concerns a tablet comprising two distinct segments. More particularly the invention relates to combinations of two pharmaceutical substances and methods of treatment of allergic disorders.