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公开(公告)号：WO2010096418A3
公开(公告)日：2012-06-14
申请号：PCT/US2010024377
申请日：2010-02-17
Applicant: UCB PHARMA SA , LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHAW STEPHEN GRAHAM , SHPEKTOR DIANA , ZHANG YI
Inventor： LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHAW STEPHEN GRAHAM , SHPEKTOR DIANA , ZHANG YI
IPC: C07K16/28 , A61K39/395 , C07K16/00
CPC classification number: C07K16/2878 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/70578 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
Abstract translation: 本发明涉及对人OX40的抗原决定簇具有特异性的抗体分子，抗体分子的治疗用途以及产生所述抗体分子的方法。
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公开(公告)号：EP2398498A4
公开(公告)日：2013-05-01
申请号：EP10744211
申请日：2010-02-17
Applicant: UCB PHARMA SA
Inventor： LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHAW STEPHEN GRAHAM , SHPEKTOR DIANA , ZHANG YI
CPC classification number: C07K16/2878 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K14/70578 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
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公开(公告)号：BRPI1008692A2
公开(公告)日：2016-03-08
申请号：BRPI1008692
申请日：2010-02-17
Applicant: UCB PHARMA SA
Inventor： LAWSON ALASTAIR GRIFFITHS , POPPLEWELL ANDREW GEORGE , NESBITT ANDREW MALCOLM , SHPEKTOR DIANA , SHAW STEPHEN GRAHAM , ZHANG YI
IPC: A61K39/395 , C07K16/00 , C07K16/28
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公开(公告)号：UA107341C2
公开(公告)日：2014-12-25
申请号：UAA201111078
申请日：2010-02-17
Applicant: UCB PHARMA SA
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公开(公告)号：SG2014014708A
公开(公告)日：2014-05-29
申请号：SG2014014708
申请日：2010-02-17
Applicant: UCB PHARMA SA
Inventor： SHAW STEVAN GRAHAM , LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHPEKTOR DIANA , ZHANG YI
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
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Patent Agency Ranking
公开(公告)号：EA018044B1
公开(公告)日：2013-05-30
申请号：EA200801427
申请日：2006-12-04
Applicant: UCB PHARMA SA
Inventor： GELINAS RICHARD EVAN , SINGHAL MITRA CHOUDHURY , ZHANG YI , POPPLEWELL ANDREW GEORGE , ADAMS RALPH
IPC: C07K16/24
Abstract: Визобретенииописанымолекулыантител, обладающиеспецифичностьюв отношенииантигенныхдетерминантИЛ-6, терапевтическиеприменениямолекулантители способыполученияуказанныхмолекулантител.
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公开(公告)号：ZA201105500B
公开(公告)日：2012-10-31
申请号：ZA201105500
申请日：2011-07-26
Applicant: UCB PHARMA SA
Inventor： LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHPEKTOR DIANA , ZHANG YI , SHAW STEVAN GRAHAM
IPC: A61K20060101 , A61P20060101 , C07H20060101 , C07K20060101 , C12N20060101 , C12P20060101
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
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公开(公告)号：PE20120211A1
公开(公告)日：2012-03-24
申请号：PE2011001494
申请日：2010-02-17
Applicant: UCB PHARMA SA
Inventor： LAWSON ALASTAIR DAVID GRIFFITHS , NESBITT ANDREW MALCOLM , POPPLEWELL ANDREW GEORGE , SHAW STEVAN GRAHAM , SHPEKTOR DIANA , ZHANG YI
Abstract: SE REFIERE A UN ANTICUERPO ANTAGONISTA QUE SE UNE A OX40 HUMANO QUE COMPRENDE: A) UNA CADENA PESADA CUYO DOMINIO VARIABLE COMPRENDE i) UN CDR-H1 QUE TIENE LA SECUENCIA SEQ ID Nº:1, ii) UN CDR-H2 QUE TIENE LA SECUENCIA SEQ ID Nº:2 O SEQ ID Nº:20, Y iii) UN CDR-H3 QUE TIENE LA SECUENCIA SEQ ID Nº:3; Y B) UNA CADENA LIGERA CUYO DOMINIO VARIABLE COMPRENDE i) UN CDR-L1 QUE TIENE LA SECUENCIA SEQ ID Nº:4 O SEQ ID Nº:21, ii) UN CDR-L2 QUE TIENE LA SECUENCIA SEQ ID Nº:5, Y iii) UN CDR-L3 QUE TIENE LA SECUENCIA SEQ ID Nº:6. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA SIENDO UTIL EN EL TRATAMIENTO DE ARTRITIS REUMATOIDE, ASMA, ENFERMEDAD DE ALZHEIMER, ENFERMEDAD DE CROHN
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公开(公告)号：UA96141C2
公开(公告)日：2011-10-10
申请号：UAA200808897
申请日：2006-12-04
Applicant: UCB PHARMA SA
Inventor： GELINAS RICHARD EVAN , SINGLHAL MITRA CHOUDHURY , ZHANG YI , POPPLEWELL ANDREW GEORGE , ADAMS RALPH
Abstract: Изобретениеотноситсяк гуманизированномунейтрализующемуантителу, котороеспецифическисвязываетсяс человеческим IL-6, последовательностиДНК, котораяегокодирует, вектору, клетке-хозяину, процессуизготовленияантитела. Изобретениетакжеотноситсяк фармацевтическойкомпозиции, содержащейданноеантитело, дляпримененияв леченииилипрофилактикепатологическогорасстройства, опосредованного IL-6 илисвязанногос ростомуровня IL-6.
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公开(公告)号：ZA200804594B
公开(公告)日：2010-08-25
申请号：ZA200804594
申请日：2006-12-04
Applicant: UCB PHARMA SA
Inventor： GELINAS RICHARD EVAN , SINGHAL MITRA CHOUDHURY , ZHANG YI , POPPLEWELL ANDREW GEORGE , ADAMS RALPH
IPC: C07K20060101
Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of IL-6, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
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